Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.
about
Small molecule inhibitors of aurora-a induce proteasomal degradation of N-myc in childhood neuroblastomaBypass of senescence by the polycomb group protein CBX8 through direct binding to the INK4A-ARF locusUBAP2L is a novel BMI1-interacting protein essential for hematopoietic stem cell activityShort mitochondrial ARF triggers Parkin/PINK1-dependent mitophagyRecognition of UbcH5c and the nucleosome by the Bmi1/Ring1b ubiquitin ligase complexPTEN inhibits BMI1 function independently of its phosphatase activitySeveral distinct polycomb complexes regulate and co-localize on the INK4a tumor suppressor locusStructure and E3-ligase activity of the Ring-Ring complex of polycomb proteins Bmi1 and Ring1bBmi-1 promotes neural stem cell self-renewal and neural development but not mouse growth and survival by repressing the p16Ink4a and p19Arf senescence pathways.Epigenetic regulation of the INK4b-ARF-INK4a locus: in sickness and in healthCellular senescence and tumor suppressor gene p16Stem cells of ependymomaHmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf ExpressionThe Polycomb group proteins bind throughout the INK4A-ARF locus and are disassociated in senescent cellsMel-18, a polycomb group protein, regulates cell proliferation and senescence via transcriptional repression of Bmi-1 and c-Myc oncoproteinsTargeting EZH2 in cancerA Novel Aspect of Tumorigenesis-BMI1 Functions in Regulating DNA Damage ResponseGenetic regulation of thymocyte progenitor agingEpithelial-mesenchymal transition and cancer stemness: the Twist1-Bmi1 connectionCoordinated control of self-renewal and differentiation of neural stem cells by Myc and the p19ARF-p53 pathwayBmi1 regulates memory CD4 T cell survival via repression of the Noxa geneEzh2 orchestrates gene expression for the stepwise differentiation of tissue-specific stem cellsGFAP-Cre-mediated transgenic activation of Bmi1 results in pituitary tumorsIncreasing p16INK4a expression decreases forebrain progenitors and neurogenesis during ageingBmi1 Loss in the Organ of Corti Results in p16ink4a Upregulation and Reduced Cell Proliferation of Otic Progenitors In Vitro.Temporal and epigenetic regulation of neurodevelopmental plasticity.A functional screen for regulators of CKDN2A reveals MEOX2 as a transcriptional activator of INK4a.Neuro-muscular differentiation of adult porcine skin derived stem cell-like cells.Distinct and separable roles for EZH2 in neurogenic astrogliaProspective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain.Primary brain tumors, neural stem cell, and brain tumor cancer cells: where is the link?Epigenetic regulation of adult neural stem cells: implications for Alzheimer's disease.The serotonin1A receptor gene as a genetic and prenatal maternal environmental factor in anxiety.p53 interaction with JMJD3 results in its nuclear distribution during mouse neural stem cell differentiation.Bmi1 regulates mitochondrial function and the DNA damage response pathwayBmi1 is expressed in postnatal myogenic satellite cells, controls their maintenance and plays an essential role in repeated muscle regenerationStem cells and the developing mammary gland.Bmi-1 absence causes premature brain degenerationSmall-molecule blocks malignant astrocyte proliferation and induces neuronal gene expressionImmature B-cell progenitors survive oncogenic stress and efficiently initiate Ph+ B-acute lymphoblastic leukemia
P2860
Q24296639-99711E7F-8B56-4C14-BB85-BBAAADB36631Q24298715-FD6A50B7-8E42-4253-86B8-2663E684AED5Q24303456-100420CA-D988-436B-8F92-786188FF8206Q24303986-2C171D4C-1D82-4193-86C5-0007E647CE9FQ24315785-6EBBD77C-4134-4D76-B6E3-C751BE767899Q24315949-40BFDFE7-C74D-4F46-A52C-7F73751BF458Q24317899-D1D4CB48-2919-4733-ACED-7BD6DA516DE5Q24337331-587627F2-49E8-462C-816D-6ED158BE8356Q24529593-65081C81-73CC-4D9A-B226-4C39E64F617BQ24604190-9FA56203-B677-474A-8B19-3BAFB7CC3E33Q24629853-8B3222D0-8943-4E80-AA76-D7C4F4AA115BQ24653517-8543F89B-4BED-4BD4-91F4-9D527010564BQ24658265-CCADA45E-147F-4DA0-819C-8893BF199B78Q24680814-35B7FE4A-77A5-4BD7-8D48-2EB12C171823Q24681882-43E99EF2-1624-434A-A66D-3DF6CD518E84Q26769027-273BAF62-F3BC-43B2-A416-E0C2E40D13A3Q26774980-B6C1C725-36AE-4667-AFE9-09781B0B563EQ26853420-6BDADAB8-2CAE-40CD-BDC1-F0D3DA9D5B45Q28248085-E7D8DEC5-2937-4EA1-80BC-D5A77B6EC324Q28581842-6719C2AD-EEBF-4DCF-BB13-9A74DAF626BEQ28588527-2C258BEC-A44F-40F2-B5E3-EECEB03B306FQ28589370-A874CE8F-0AF6-4EA9-B35F-6082DDBABFFBQ28730123-196022A8-B70B-4123-A058-D908CDF249E1Q29615155-40C73A77-0277-4895-98D1-707A1D51C7FEQ30371668-0E5B9F4F-859D-420D-AAA1-2310E562B062Q33274777-A8348058-74C1-4BAC-BA49-8E4793134DAAQ33425898-13F16052-F017-4C1A-9477-ED6A0AEA8ED9Q33529012-6D7FCE19-E3FA-4EF4-93B4-050BDFC6B027Q33655867-9C6EFE55-2ED6-4E8C-8517-220AA99725D8Q33687252-8B55CBD3-134A-4C23-B690-E386A55EAD83Q33729734-7AC9666A-13A4-4243-BF4A-78167B66BE9CQ33841944-3E500857-6E45-4F06-ADF7-936A3A0C265AQ33842128-815C43E4-FB1A-4AE6-9A86-57A9BDF0EE4DQ33869591-206CD1F2-0D05-4A6A-8B29-5B4BB70833B5Q34017298-B0BBA508-C291-42AF-810F-0375C10F6866Q34077764-9D996803-D2C1-44FF-BB41-24E8172808BFQ34166067-F8A58B19-BA46-4933-ABFE-71A8D2B6ACFDQ34171573-5589FB5E-5813-4D6D-95AF-6BC725E9550CQ34171945-F6DB43C2-5DBB-4F9F-AEE9-E749E878FC69Q34193548-125C6240-7421-4C71-A6A6-F65A894F0A76
P2860
Ink4a and Arf differentially affect cell proliferation and neural stem cell self-renewal in Bmi1-deficient mice.
description
2005 nî lūn-bûn
@nan
2005 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի հունիսին հրատարակված գիտական հոդված
@hy
2005年の論文
@ja
2005年論文
@yue
2005年論文
@zh-hant
2005年論文
@zh-hk
2005年論文
@zh-mo
2005年論文
@zh-tw
2005年论文
@wuu
name
Ink4a and Arf differentially a ...... renewal in Bmi1-deficient mice
@nl
Ink4a and Arf differentially a ...... enewal in Bmi1-deficient mice.
@ast
Ink4a and Arf differentially a ...... enewal in Bmi1-deficient mice.
@en
type
label
Ink4a and Arf differentially a ...... renewal in Bmi1-deficient mice
@nl
Ink4a and Arf differentially a ...... enewal in Bmi1-deficient mice.
@ast
Ink4a and Arf differentially a ...... enewal in Bmi1-deficient mice.
@en
prefLabel
Ink4a and Arf differentially a ...... renewal in Bmi1-deficient mice
@nl
Ink4a and Arf differentially a ...... enewal in Bmi1-deficient mice.
@ast
Ink4a and Arf differentially a ...... enewal in Bmi1-deficient mice.
@en
P2093
P2860
P3181
P356
P1433
P1476
Ink4a and Arf differentially a ...... enewal in Bmi1-deficient mice.
@en
P2093
Carly Leung
Danielle Hulsman
Ellen Tanger
Jacqueline J L Jacobs
Karin Kieboom
Maarten van Lohuizen
Merel E Valk-Lingbeek
Petra P M van der Stoop
Silvia Marino
Sophia W M Bruggeman
P2860
P304
P3181
P356
10.1101/GAD.1299305
P577
2005-06-01T00:00:00Z