The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas
about
Genome-wide promoter analysis of the SOX4 transcriptional network in prostate cancer cellsPax6 controls the expression of critical genes involved in pancreatic {alpha} cell differentiation and functionOrganogenesis relies on SoxC transcription factors for the survival of neural and mesenchymal progenitorsThe three SoxC proteins--Sox4, Sox11 and Sox12--exhibit overlapping expression patterns and molecular propertiesSox12 deletion in the mouse reveals nonreciprocal redundancy with the related Sox4 and Sox11 transcription factorsLong-range gene regulation links genomic type 2 diabetes and obesity risk regions to HHEX, SOX4, and IRX3Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factorsSox17 regulates insulin secretion in the normal and pathologic mouse β cellClass-C SOX transcription factors control GnRH gene expression via the intronic transcriptional enhancerRole of the transcription factor sox4 in insulin secretion and impaired glucose toleranceSequential requirement of Sox4 and Sox11 during development of the sympathetic nervous systemSox4 links tumor suppression to accelerated aging in mice by modulating stem cell activationAnalysis of beta-cell gene expression reveals inflammatory signaling and evidence of dedifferentiation following human islet isolation and cultureDetection of molecular paths associated with insulitis and type 1 diabetes in non-obese diabetic mouseInteraction between Hhex and SOX13 modulates Wnt/TCF activityThe Sex-determining region Y-box 4 and homeobox C6 transcriptional networks in prostate cancer progression: crosstalk with the Wnt, Notch, and PI3K pathwaysThe HMG-box transcription factor Sox4b is required for pituitary expression of gata2a and specification of thyrotrope and gonadotrope cells in zebrafish.Pheochromocytoma in rats with multiple endocrine neoplasia (MENX) shares gene expression patterns with human pheochromocytoma.Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.Mutation of murine Sox4 untranslated regions results in partially penetrant perinatal lethality.A mouse model for monitoring islet cell genesis and developing therapies for diabetesSox9: a master regulator of the pancreatic program.Zebrafish mnx1 controls cell fate choice in the developing endocrine pancreas.Novel role for SGK3 in glucose homeostasis revealed in SGK3/Akt2 double-null miceHepatitis B virus replication and sex-determining region Y box 4 production are tightly controlled by a novel positive feedback mechanism.Common binding by redundant group B Sox proteins is evolutionarily conserved in Drosophila.Sry-box (Sox) transcription factors in gastrointestinal physiology and disease.Sox9 coordinates a transcriptional network in pancreatic progenitor cellsA Mouse Model of Targeted Musashi1 Expression in Whole Intestinal Epithelium Suggests Regulatory Roles in Cell Cycle and StemnessBlockade of SOX4 mediated DNA repair by SPARC enhances radioresponse in medulloblastomaTranscription factors SOX4 and SOX11 function redundantly to regulate the development of mouse retinal ganglion cells.On the origin of the beta cell.Expression profiling of zebrafish sox9 mutants reveals that Sox9 is required for retinal differentiation.On the diabetic menu: zebrafish as a model for pancreas development and function.Development of insulin-producing cells from primitive biologic precursors.Critical roles for SoxC transcription factors in development and cancer.Zebrafish as a genomics model for human neurological and polygenic disorders.Mouse models and type 2 diabetes: translational opportunities.Nutrition-/diet-induced changes in gene expression in pancreatic β-cells.Pleiotropic function of SRY-related HMG box transcription factor 4 in regulation of tumorigenesis.
P2860
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P2860
The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/01)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في ديسمبر 2005)
@ar
name
The HMG box transcription fact ...... ment of the endocrine pancreas
@ast
The HMG box transcription fact ...... ment of the endocrine pancreas
@en
The HMG box transcription fact ...... ment of the endocrine pancreas
@nl
type
label
The HMG box transcription fact ...... ment of the endocrine pancreas
@ast
The HMG box transcription fact ...... ment of the endocrine pancreas
@en
The HMG box transcription fact ...... ment of the endocrine pancreas
@nl
prefLabel
The HMG box transcription fact ...... ment of the endocrine pancreas
@ast
The HMG box transcription fact ...... ment of the endocrine pancreas
@en
The HMG box transcription fact ...... ment of the endocrine pancreas
@nl
P2093
P921
P1433
P1476
The HMG box transcription fact ...... ment of the endocrine pancreas
@en
P2093
Anna Kalousova
Caroline Mrejen
Francis C. Lynn
Hans C. Clevers
Juehu Wang
Katherine Y. Yang
Maria E. Wilson
Michael S. German
Vasso Episkopou
P304
P356
10.2337/DIABETES.54.12.3402
P407
P577
2005-12-01T00:00:00Z