Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a. - Wikidata - wikimedia - TriplyDB

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

http://www.wikidata.org/entity/Q34472119

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Multipotent pancreas progenitors: Inconclusive but pivotal topic Pancreatic stem cells remain unresolved Cell cycle-dependent differentiation dynamics balances growth and endocrine differentiation in the pancreas Insm1 promotes endocrine cell differentiation by modulating the expression of a network of genes that includes Neurog3 and Ripply3 Small-molecule inhibitors of the cystic fibrosis transmembrane conductance regulator increase pancreatic endocrine cell development in rat and mouse Expansion and conversion of human pancreatic ductal cells into insulin-secreting endocrine cells.Precommitment low-level Neurog3 expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells.Contribution of a non-β-cell source to β-cell mass during pregnancy.Novel pancreatic endocrine maturation pathways identified by genomic profiling and causal reasoning.Obestatin enhances in vitro generation of pancreatic islets through regulation of developmental pathways.Genome-wide DNA methylation analysis of human pancreatic islets from type 2 diabetic and non-diabetic donors identifies candidate genes that influence insulin secretion.Gαi/o-coupled receptor signaling restricts pancreatic β-cell expansion Human fucci pancreatic Beta cell lines: new tools to study Beta cell cycle and terminal differentiation.G protein-coupled receptor signaling and sphingosine-1-phosphate play a phylogenetically conserved role in endocrine pancreas morphogenesis A small molecule differentiation inducer increases insulin production by pancreatic β cells Competence of failed endocrine progenitors to give rise to acinar but not ductal cells is restricted to early pancreas development p21, an important mediator of quiescence during pituitary tumor formation, is dispensable for normal pituitary development during embryogenesis.Dissecting Human Gene Functions Regulating Islet Development With Targeted Gene Transduction EphB3 marks delaminating endocrine progenitor cells in the developing pancreas Postnatal Pancreas of Mice Contains Tripotent Progenitors Capable of Giving Rise to Duct, Acinar, and Endocrine Cells In Vitro.Deconstructing pancreas developmental biology.Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche.Exploiting Expression of Hippo Effector, Yap, for Expansion of Functional Islet Mass.Colony-forming cells in the adult mouse pancreas are expandable in Matrigel and form endocrine/acinar colonies in laminin hydrogel Pak3 promotes cell cycle exit and differentiation of β-cells in the embryonic pancreas and is necessary to maintain glucose homeostasis in adult mice.miR-18a counteracts AKT and ERK activation to inhibit the proliferation of pancreatic progenitor cells Pancreatic stem cells: from possible to probable.Lineage determinants in early endocrine development.Gene regulatory networks governing pancreas development.Can the 'neuron theory' be complemented by a universal mechanism for generic neuronal differentiation.Chronological analysis with fluorescent timer reveals unique features of newly generated β-cells.Reprogramming human gallbladder cells into insulin-producing β-like cells.Pancreatic Mesenchyme Regulates Islet Cellular Composition in a Patched/Hedgehog-Dependent Manner.Multi-site Neurogenin3 Phosphorylation Controls Pancreatic Endocrine Differentiation.Activation of GLP-1 and gastrin signalling induces in vivo reprogramming of pancreatic exocrine cells into beta cells in mice.Phosphorylation of NEUROG3 Links Endocrine Differentiation to the Cell Cycle in Pancreatic Progenitors.Islet cells share promoter hypomethylation independently of expression, but exhibit cell-type-specific methylation in enhancers.FUCCI tracking shows cell-cycle-dependent Neurog3 variation in pancreatic progenitors.Differentiation of Islet Progenitors Regulated by Nicotinamide into Transcriptome-Verified β Cells That Ameliorate Diabetes.Lineage dynamics of murine pancreatic development at single-cell resolution

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Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

http://www.wikidata.org/entity/Q34472119

description

2010 nî lūn-bûn

@nan

2010 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած

@hyw

2010 թվականի դեկտեմբերին հրատարակված գիտական հոդված

@hy

2010年の論文

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2010年論文

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2010年論文

@zh-hant

2010年論文

@zh-hk

2010年論文

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2010年論文

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2010年论文

@wuu

name

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@ast

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@en

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@nl

type

label

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@ast

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@en

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@nl

prefLabel

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@ast

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@en

Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@nl

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Proceedings of the National Academy of Sciences of the United States of America

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Neurogenin3 inhibits proliferation in endocrine progenitors by inducing Cdkn1a.

@en

P2093

Hail Kim

http://www.w3.org/2001/XMLSchema#string

Michael S German

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Takeshi Miyatsuka

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Yasuhiro Kosaka

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P2860

Rfx6 directs islet formation and insulin production in mice and humans

neurogenin3 is required for the development of the four endocrine cell lineages of the pancreas

WAF1, a potential mediator of p53 tumor suppression

In vivo reprogramming of adult pancreatic exocrine cells to beta-cells

Notch signalling controls pancreatic cell differentiation

The HMG box transcription factor Sox4 contributes to the development of the endocrine pancreas

Neurogenin 3 is essential for the proper specification of gastric enteroendocrine cells and the maintenance of gastric epithelial cell identity

Independent development of pancreatic alpha- and beta-cells from neurogenin3-expressing precursors: a role for the notch pathway in repression of premature differentiation

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

p21 in cancer: intricate networks and multiple activities

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