Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse.
about
The HNF1beta transcription factor has several domains involved in nephrogenesis and partially rescues Pax8/lim1-induced kidney malformationsControl of differentiation-induced calbindin-D9k gene expression in Caco-2 cells by cdx-2 and HNF-1alphaPancreatic-duodenal homeobox 1 regulates expression of liver receptor homolog 1 during pancreas developmentThe mouse RNase 4 and RNase 5/ang 1 locus utilizes dual promoters for tissue-specific expressionMolecular pathogenesis of hepatic adenomas and its implications for surgical managementEpistasis of transcriptomes reveals synergism between transcriptional activators Hnf1alpha and Hnf4alphaBi-allelic inactivation of TCF1 in hepatic adenomasCharacterization of the human OATP-C (SLC21A6) gene promoter and regulation of liver-specific OATP genes by hepatocyte nuclear factor 1 alphaCloning of the human claudin-2 5'-flanking region revealed a TATA-less promoter with conserved binding sites in mouse and human for caudal-related homeodomain proteins and hepatocyte nuclear factor-1alphaDissociation of the hepatic phenotype from HNF4 and HNF1alpha expressionHepatocyte Nuclear Factor 1A Is a Cell-Intrinsic Transcription Factor Required for B Cell Differentiation and Development in MiceLoss of hepatocyte-nuclear-factor-1alpha impacts on adult mouse intestinal epithelial cell growth and cell lineages differentiationTranscriptional regulation of the human hepatic lipase (LIPC) gene promoterActivity of hepatocyte nuclear factor 1alpha and hepatocyte nuclear factor 1beta isoforms is differently affected by the inhibition of protein phosphatases 1/2APlasticity and expanding complexity of the hepatic transcription factor network during liver developmentA molecular link between the common phenotypes of type 1 glycogen storage disease and HNF1alpha-null miceHNF1alpha is involved in tissue-specific regulation of CFTR gene expressionFunctions of HNF1 family members in differentiation of the visceral endoderm cell lineageHepatocyte nuclear factor 1alpha controls the expression of terminal complement genesA nutrient-sensitive interaction between Sirt1 and HNF-1α regulates Crp expressionHepatic nuclear factor 1-alpha directs nucleosomal hyperacetylation to its tissue-specific transcriptional targetsHepatocyte nuclear factor-1alpha is required for expression but dispensable for histone acetylation of the lactase-phlorizin hydrolase gene in vivoGata4 and Hnf1alpha are partially required for the expression of specific intestinal genes during developmentGrowth hormone (GH) receptor knockout mice reveal actions of GH in lung development.Hepatitis C virus infection suppresses GLUT2 gene expression via downregulation of hepatocyte nuclear factor 1α.Isolation and functional analysis of human HMBOX1, a homeobox containing protein with transcriptional repressor activity.Targeted deficiency of the transcriptional activator Hnf1alpha alters subnuclear positioning of its genomic targetsHNF4alpha and HNF1alpha dysfunction as a molecular rational for cyclosporine induced posttransplantation diabetes mellitus.Many faces of monogenic diabetesCytochrome P450-null mice.Distinct regulation of hepatic nuclear factor 1alpha by NKX6.1 in pancreatic beta cells.Nuclear covalently closed circular viral genomic DNA in the liver of hepatocyte nuclear factor 1 alpha-null hepatitis B virus transgenic miceDominant-negative suppression of HNF-1alpha function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic beta-cell line.Alpha/beta interferon differentially modulates the clearance of cytoplasmic encapsidated replication intermediates and nuclear covalently closed circular hepatitis B virus (HBV) DNA from the livers of hepatocyte nuclear factor 1alpha-null HBV transgRole of Wnt/β-catenin signaling in liver metabolism and cancerDifferential activation of intestinal gene promoters: functional interactions between GATA-5 and HNF-1 alpha.A transcription factor regulatory circuit in differentiated pancreatic cells.HNF1α inhibition triggers epithelial-mesenchymal transition in human liver cancer cell lines.HNF-1alpha G319S, a transactivation-deficient mutant, is associated with altered dynamics of diabetes onset in an Oji-Cree community.MicroRNA-194 is a target of transcription factor 1 (Tcf1, HNF1α) in adult liver and controls expression of frizzled-6.
P2860
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P2860
Laron dwarfism and non-insulin-dependent diabetes mellitus in the Hnf-1alpha knockout mouse.
description
1998 nî lūn-bûn
@nan
1998 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի մայիսին հրատարակված գիտական հոդված
@hy
1998年の論文
@ja
1998年論文
@yue
1998年論文
@zh-hant
1998年論文
@zh-hk
1998年論文
@zh-mo
1998年論文
@zh-tw
1998年论文
@wuu
name
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse
@nl
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse.
@ast
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse.
@en
type
label
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse
@nl
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse.
@ast
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse.
@en
prefLabel
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse
@nl
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse.
@ast
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse.
@en
P2093
P2860
P3181
P356
P1476
Laron dwarfism and non-insulin ...... the Hnf-1alpha knockout mouse.
@en
P2093
P2860
P304
P3181
P356
10.1128/MCB.18.5.3059
P407
P577
1998-05-01T00:00:00Z