A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development
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Transcription factor genes Smad4 and Gata4 cooperatively regulate cardiac valve development. [corrected]Genetics of congenital heart disease: the glass half emptyOf mice and men: molecular genetics of congenital heart diseaseGene regulatory networks in cardiac conduction system developmentTherapeutic potential of Pnmt+ primer cells for neuro/myocardial regenerationThe cardiac conduction systemCongenital heart disease-causing Gata4 mutation displays functional deficits in vivoInhibitor of DNA binding 2 is a small molecule-inducible modulator of peroxisome proliferator-activated receptor-gamma expression and adipocyte differentiationSlow progressive conduction and contraction defects in loss of Nkx2-5 mice after cardiomyocyte terminal differentiationTinman/Nkx2-5 acts via miR-1 and upstream of Cdc42 to regulate heart function across speciesPerinatal loss of Nkx2-5 results in rapid conduction and contraction defectsAblation of Nkx2-5 at mid-embryonic stage results in premature lethality and cardiac malformationIroquois homeobox gene 3 establishes fast conduction in the cardiac His-Purkinje network.The Popeye domain containing 2 (popdc2) gene in zebrafish is required for heart and skeletal muscle development.Reciprocal myocardial-endocardial interactions pattern the delay in atrioventricular junction conduction.Genomic analysis distinguishes phases of early development of the mouse atrio-ventricular canal.Development of electrocardiogram intervals during growth of FVB/N neonate mice.Genome-wide association study of PR interval.Myocardial deletion of transcription factor CHF1/Hey2 results in altered myocyte action potential and mild conduction system expansion but does not alter conduction system function or promote spontaneous arrhythmias.Splice variants of enigma homolog, differentially expressed during heart development, promote or prevent hypertrophy.The serum response factor and a putative novel transcription factor regulate expression of the immediate-early gene Arc/Arg3.1 in neurons.Expression of sumoylation deficient Nkx2.5 mutant in Nkx2.5 haploinsufficient mice leads to congenital heart defects.Synergistic activation of cardiac genes by myocardin and Tbx5.Tbx2 and Tbx3 induce atrioventricular myocardial development and endocardial cushion formationThe App-Runx1 region is critical for birth defects and electrocardiographic dysfunctions observed in a Down syndrome mouse model.Integrating genetic, transcriptional, and functional analyses to identify 5 novel genes for atrial fibrillation.High fat diet rescues disturbances to metabolic homeostasis and survival in the Id2 null mouse in a sex-specific manner.MyoR modulates cardiac conduction by repressing Gata4.Functional, anatomical, and molecular investigation of the cardiac conduction system and arrhythmogenic atrioventricular ring tissue in the rat heart.NKX2-5 mutations in an inbred consanguineous population: genetic and phenotypic diversity.c.620C>T mutation in GATA4 is associated with congenital heart disease in South India.p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiationEfficient Generation of Cardiac Purkinje Cells from ESCs by Activating cAMP Signaling.Enhanced desumoylation in murine hearts by overexpressed SENP2 leads to congenital heart defects and cardiac dysfunction.Angiotensin II Induced Cardiac Dysfunction on a Chip.Probing the polygenic basis of cardiomyopathies in Drosophila.Phenotypically silent Cre recombination within the postnatal ventricular conduction systemSpatiotemporal regulation of an Hcn4 enhancer defines a role for Mef2c and HDACs in cardiac electrical patterningSingle nucleotide polymorphism of NKX2-5 gene with sporadic congenital heart disease in Chinese Bai population.Mechanisms contributing to myocardial potassium channel diversity, regulation and remodeling
P2860
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P2860
A molecular pathway including Id2, Tbx5, and Nkx2-5 required for cardiac conduction system development
description
2007 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
@ast
im Juni 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/06/29)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/06/29)
@nl
наукова стаття, опублікована в червні 2007
@uk
مقالة علمية (نشرت في 29-6-2007)
@ar
name
A molecular pathway including ...... conduction system development
@ast
A molecular pathway including ...... conduction system development
@en
A molecular pathway including ...... conduction system development
@nl
type
label
A molecular pathway including ...... conduction system development
@ast
A molecular pathway including ...... conduction system development
@en
A molecular pathway including ...... conduction system development
@nl
prefLabel
A molecular pathway including ...... conduction system development
@ast
A molecular pathway including ...... conduction system development
@en
A molecular pathway including ...... conduction system development
@nl
P2093
P921
P3181
P1433
P1476
A molecular pathway including ...... conduction system development
@en
P2093
Charles Berul
Christine E. Seidman
Cordula M. Wolf
Ivan P. G. Moskowitz
J. G. Seidman
Jae B. Kim
Marcelo A. Nobrega
Meredith L. Moore
Michael A. Peterson
Seigo Izumo
P304
P3181
P356
10.1016/J.CELL.2007.04.036
P407
P50
P577
2007-06-29T00:00:00Z