Neurofascins are required to establish axonal domains for saltatory conduction
about
MAP kinase pathway-dependent phosphorylation of the L1-CAM ankyrin binding site regulates neuronal growthDisrupted axo-glial junctions result in accumulation of abnormal mitochondria at nodes of ranvierNeurofascin assembles a specialized extracellular matrix at the axon initial segmentMechanisms of sodium channel clustering and its influence on axonal impulse conductionTrafficking regulates the subcellular distribution of voltage-gated sodium channels in primary sensory neuronsB Cells and Autoantibodies in Multiple SclerosisNeuro-glial interactions at the nodes of Ranvier: implication in health and diseasesHDAC1/2-Dependent P0 Expression Maintains Paranodal and Nodal Integrity Independently of Myelin Stability through Interactions with NeurofascinsMolecular regulators of nerve conduction - Lessons from inherited neuropathies and rodent genetic modelsA glial signal consisting of gliomedin and NrCAM clusters axonal Na+ channels during the formation of nodes of RanvierMultiple molecular interactions determine the clustering of Caspr2 and Kv1 channels in myelinated axonsIn vivo deletion of immunoglobulin domains 5 and 6 in neurofascin (Nfasc) reveals domain-specific requirements in myelinated axonsNodes of Ranvier and axon initial segments are ankyrin G-dependent domains that assemble by distinct mechanismsDisruption of axo-glial junctions causes cytoskeletal disorganization and degeneration of Purkinje neuron axonsCNTNAP1 mutations cause CNS hypomyelination and neuropathy with or without arthrogryposis.Doublecortin (DCX) mediates endocytosis of neurofascin independently of microtubule binding.Neuronal Ig/Caspr recognition promotes the formation of axoaxonic synapses in mouse spinal cord.Electron tomographic analysis of cytoskeletal cross-bridges in the paranodal region of the node of Ranvier in peripheral nerves.Contactins: emerging key roles in the development and function of the nervous system.Localization and targeting of voltage-dependent ion channels in mammalian central neurons.Neurofascin IgG4 antibodies in CIDP associate with disabling tremor and poor response to IVIg.Ankyrin-G directly binds to kinesin-1 to transport voltage-gated Na+ channels into axons.In vivo assembly of the axon initial segment in motor neuronsPostnatal Loss of Neuronal and Glial Neurofascins Differentially Affects Node of Ranvier Maintenance and Myelinated Axon Function.Axonal Membranes and Their Domains: Assembly and Function of the Axon Initial Segment and Node of Ranvier.Novel forms of neurofascin 155 in the central nervous system: alterations in paranodal disruption models and multiple sclerosisNo effect of genetic deletion of contactin-associated protein (CASPR) on axonal orientation and synaptic plasticity.Myelination and regional domain differentiation of the axon.A central role for Necl4 (SynCAM4) in Schwann cell-axon interaction and myelination.Organization of myelinated axons by Caspr and Caspr2 requires the cytoskeletal adapter protein 4.1BSpatiotemporal ablation of myelinating glia-specific neurofascin (Nfasc NF155) in mice reveals gradual loss of paranodal axoglial junctions and concomitant disorganization of axonal domains.Organization and maintenance of molecular domains in myelinated axonsRole of transverse bands in maintaining paranodal structure and axolemmal domain organization in myelinated nerve fibers: effect on longevity in dysmyelinated mutant miceLoss of glial neurofascin155 delays developmental synapse elimination at the neuromuscular junctionA model of tight junction function in central nervous system myelinated axonsNodes of Ranvier act as barriers to restrict invasion of flanking paranodal domains in myelinated axons.Glial ankyrins facilitate paranodal axoglial junction assemblyA hierarchy of ankyrin-spectrin complexes clusters sodium channels at nodes of RanvierAcceleration of conduction velocity linked to clustering of nodal components precedes myelination.Perlecan is recruited by dystroglycan to nodes of Ranvier and binds the clustering molecule gliomedin.
P2860
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P2860
Neurofascins are required to establish axonal domains for saltatory conduction
description
2005 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im Dezember 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/12/08)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/12/08)
@nl
наукова стаття, опублікована в грудні 2005
@uk
مقالة علمية (نشرت في 8-12-2005)
@ar
name
Neurofascins are required to establish axonal domains for saltatory conduction
@ast
Neurofascins are required to establish axonal domains for saltatory conduction
@en
Neurofascins are required to establish axonal domains for saltatory conduction
@nl
type
label
Neurofascins are required to establish axonal domains for saltatory conduction
@ast
Neurofascins are required to establish axonal domains for saltatory conduction
@en
Neurofascins are required to establish axonal domains for saltatory conduction
@nl
prefLabel
Neurofascins are required to establish axonal domains for saltatory conduction
@ast
Neurofascins are required to establish axonal domains for saltatory conduction
@en
Neurofascins are required to establish axonal domains for saltatory conduction
@nl
P2093
P3181
P1433
P1476
Neurofascins are required to establish axonal domains for saltatory conduction
@en
P2093
Andrew J H Smith
Barbara Zonta
David F Cottrell
Diane L Sherman
Peter J Brophy
Richard Johnson
Shona Melrose
Stephen Meek
Steven Tait
Wendy B Macklin
P304
P3181
P356
10.1016/J.NEURON.2005.10.019
P407
P577
2005-12-01T00:00:00Z