The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs
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Isoform diversity and regulation in peripheral and central neurons revealed through RNA-SeqMEF2 transcription factors: developmental regulators and emerging cancer genesInvestigating the transcriptional control of cardiovascular developmentOf mice and men: molecular genetics of congenital heart diseaseSystems-based technologies in profiling the stem cell molecular framework for cardioregenerative medicineMesodermal iPSC-derived progenitor cells functionally regenerate cardiac and skeletal muscleIslet-1 may function as an assistant factor for histone acetylation and regulation of cardiac development-related transcription factor Mef2c expressionGenetic networks governing heart development.ChIPBase: a database for decoding the transcriptional regulation of long non-coding RNA and microRNA genes from ChIP-Seq data.Generation of Functional Human Cardiac Progenitor Cells by High-Efficiency Protein Transduction.Large-scale quality analysis of published ChIP-seq data.Point mutations in murine Nkx2-5 phenocopy human congenital heart disease and induce pathogenic Wnt signaling.Increased frequency of de novo copy number variants in congenital heart disease by integrative analysis of single nucleotide polymorphism array and exome sequence dataInferring dynamic gene regulatory networks in cardiac differentiation through the integration of multi-dimensional data.Decoding the complex genetic causes of heart diseases using systems biologyNatural variation of histone modification and its impact on gene expression in the rat genome.Global transcriptomic analysis of induced cardiomyocytes predicts novel regulators for direct cardiac reprogramming.Rbm20-deficient cardiogenesis reveals early disruption of RNA processing and sarcomere remodeling establishing a developmental etiology for dilated cardiomyopathy.Steroid receptor coactivator-2 is a dual regulator of cardiac transcription factor function.Disruption of myocardial Gata4 and Tbx5 results in defects in cardiomyocyte proliferation and atrioventricular septation.Epigenetic features are significantly associated with alternative splicing.Epigenetic regulation of cardiac myocyte differentiation.COPS: detecting co-occurrence and spatial arrangement of transcription factor binding motifs in genome-wide datasets.Heart structure-specific transcriptomic atlas reveals conserved microRNA-mRNA interactions.The regulation of troponins I, C and ANP by GATA4 and Nkx2-5 in heart of hibernating thirteen-lined ground squirrels, Ictidomys tridecemlineatus.Gene expression changes controlling distinct adaptations in the heart and skeletal muscle of a hibernating mammalGene expression network analysis reveals new transcriptional regulators as novel factors in human ischemic cardiomyopathyVISIONET: intuitive visualisation of overlapping transcription factor networks, with applications in cardiogenic gene discovery.Cardiac development in zebrafish and human embryonic stem cells is inhibited by exposure to tobacco cigarettes and e-cigarettesSystems Biology Reveals MicroRNA-Mediated Gene Regulation.NKX2-5 mutations causative for congenital heart disease retain functionality and are directed to hundreds of targets.Analysis of region-specific changes in gene expression upon treatment with citalopram and desipramine reveals temporal dynamics in response to antidepressant drugs at the transcriptome levelTranscription factor-induced activation of cardiac gene expression in human c-kit+ cardiac progenitor cells.Metabolic stress in the myocardium: adaptations of gene expression.Muscle-relevant genes marked by stable H3K4me2/3 profiles and enriched MyoD binding during myogenic differentiation.Mutational screening of affected cardiac tissues and peripheral blood cells identified novel somatic mutations in GATA4 in patients with ventricular septal defectGenome-Wide Detection of Gene Coexpression Domains Showing Linkage to Regions Enriched with Polymorphic Retrotransposons in Recombinant Inbred Mouse Strains.Mild decrease in TBX20 promoter activity is a potentially protective factor against congenital heart defects in the Han Chinese population.Hierarchical approaches for systems modeling in cardiac development.MEF2B mutations in non-Hodgkin lymphoma dysregulate cell migration by decreasing MEF2B target gene activation
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P248
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P2860
The cardiac transcription network modulated by Gata4, Mef2a, Nkx2.5, Srf, histone modifications, and microRNAs
description
2011 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2011
@ast
im Februar 2011 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2011/02/01)
@sk
vědecký článek publikovaný v roce 2011
@cs
wetenschappelijk artikel (gepubliceerd op 2011/02/01)
@nl
наукова стаття, опублікована в лютому 2011
@uk
مقالة علمية (نشرت في فبراير 2011)
@ar
name
The cardiac transcription netw ...... e modifications, and microRNAs
@ast
The cardiac transcription netw ...... e modifications, and microRNAs
@en
The cardiac transcription netw ...... e modifications, and microRNAs
@nl
type
label
The cardiac transcription netw ...... e modifications, and microRNAs
@ast
The cardiac transcription netw ...... e modifications, and microRNAs
@en
The cardiac transcription netw ...... e modifications, and microRNAs
@nl
prefLabel
The cardiac transcription netw ...... e modifications, and microRNAs
@ast
The cardiac transcription netw ...... e modifications, and microRNAs
@en
The cardiac transcription netw ...... e modifications, and microRNAs
@nl
P2093
P2860
P921
P3181
P1433
P1476
The cardiac transcription netw ...... e modifications, and microRNAs
@en
P2093
Ilona Dunkel
Jenny J. Fischer
Jenny Schlesinger
Marcel Grunert
Markus Schueler
Martin Lange
Martje Tönjes
Silke R. Sperling
Tammo Krueger
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1001313
P577
2011-02-01T00:00:00Z