Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion
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Mitochondrial pyruvate transport: a historical perspective and future research directionsAssociation of NKAPL, TSPAN18, and MPC2 gene variants with schizophrenia based on new data and a meta-analysis in Han Chinese.Regulation of substrate utilization by the mitochondrial pyruvate carrierEmbryonic Lethality of Mitochondrial Pyruvate Carrier 1 Deficient Mouse Can Be Rescued by a Ketogenic Diet.MPC1 and MPC2 expressions are associated with favorable clinical outcomes in prostate cancerHepatic Mitochondrial Pyruvate Carrier 1 Is Required for Efficient Regulation of Gluconeogenesis and Whole-Body Glucose Homeostasis.Requirement for the Mitochondrial Pyruvate Carrier in Mammalian Development Revealed by a Hypomorphic Allelic Series.Mitochondrial Pyruvate Import Promotes Long-Term Survival of Antibody-Secreting Plasma Cells.Establishment of mitochondrial pyruvate carrier 1 (MPC1) gene knockout mice with preliminary gene function analyses.The TZD insulin sensitizer clue provides a new route into diabetes drug discovery.Control of intestinal stem cell function and proliferation by mitochondrial pyruvate metabolism.Mitochondrial pyruvate carrier function determines cell stemness and metabolic reprogramming in cancer cells.Pioglitazone inhibits mitochondrial pyruvate metabolism and glucose production in hepatocytes.The beneficial metabolic effects of insulin sensitizers are not attenuated by mitochondrial pyruvate carrier 2 hypomorphism.Loss of Mitochondrial Pyruvate Carrier 2 in the Liver Leads to Defects in Gluconeogenesis and Compensation via Pyruvate-Alanine Cycling.Diabetogenic milieus induce specific changes in mitochondrial transcriptome and differentiation of human pancreatic islets.Functional Properties of the Mitochondrial Carrier System.An ancestral role for the mitochondrial pyruvate carrier in glucose-stimulated insulin secretion.MPC1-like Is a Placental Mammal-specific Mitochondrial Pyruvate Carrier Subunit Expressed in Postmeiotic Male Germ Cells.MPC1, a key gene in cancer metabolism, is regulated by COUPTFII in human prostate cancer.Inhibition of the Mitochondrial Pyruvate Carrier by Tolylfluanid.Mitochondrial pyruvate carrier regulates autophagy, inflammation, and neurodegeneration in experimental models of Parkinson's disease.Human mitochondrial pyruvate carrier 2 as an autonomous membrane transporter.Energy Metabolism of the Osteoblast: Implications for Osteoporosis.Targeting energy metabolism via the mitochondrial pyruvate carrier as a novel approach to attenuate neurodegeneration.Function of mitochondrial pyruvate carriers in hepatocellular carcinoma patients.Adipose tissues of MPC1 mice display altered lipid metabolism-related enzyme expression levelsBerberine Reduces Pyruvate-driven Hepatic Glucose Production by Limiting Mitochondrial Import of Pyruvate through Mitochondrial Pyruvate Carrier 1
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P2860
Mitochondrial pyruvate carrier 2 hypomorphism in mice leads to defects in glucose-stimulated insulin secretion
description
2014 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2014
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im Juni 2014 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2014/06/26)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/06/26)
@nl
наукова стаття, опублікована в червні 2014
@uk
مقالة علمية (نشرت في 26-6-2014)
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name
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
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Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@en
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@nl
type
label
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@ast
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@en
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@nl
prefLabel
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@ast
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@en
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@nl
P2093
P2860
P921
P3181
P1433
P1476
Mitochondrial pyruvate carrier ...... e-stimulated insulin secretion
@en
P2093
Brian N. Finck
George G. Schweitzer
Jerry R. Colca
Kari T. Chambers
Kyle S. McCommis
Maria S. Remedi
Patrick A. Vigueira
Rolf F. Kletzien
Serena L. Cole
Shawn C. Burgess
P2860
P304
P3181
P356
10.1016/J.CELREP.2014.05.017
P577
2014-06-26T00:00:00Z