Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density
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The Presynaptic Microtubule Cytoskeleton in Physiological and Pathological Conditions: Lessons from Drosophila Fragile X Syndrome and Hereditary Spastic ParaplegiasProteostasis and RNA Binding Proteins in Synaptic Plasticity and in the Pathogenesis of Neuropsychiatric DisordersDysregulation and restoration of translational homeostasis in fragile X syndromeGenetic disruption of voltage-gated calcium channels in psychiatric and neurological disordersAltered Neuronal and Circuit Excitability in Fragile X Syndrome.Therapeutic Strategies in Fragile X Syndrome: From Bench to Bedside and BackThe amino-terminal structure of human fragile X mental retardation protein obtained using precipitant-immobilized imprinted polymersmTOR and MAPK: from localized translation control to epilepsyIndependent role for presynaptic FMRP revealed by an FMR1 missense mutation associated with intellectual disability and seizuresNovel RNA- and FMRP-binding protein TRF2-S regulates axonal mRNA transport and presynaptic plasticityIn vivo synaptic transmission and morphology in mouse models of Tuberous sclerosis, Fragile X syndrome, Neurofibromatosis type 1, and Costello syndromeDifferential increases of specific FMR1 mRNA isoforms in premutation carriersFunctional exofacially tagged N-type calcium channels elucidate the interaction with auxiliary α2δ-1 subunits.Emerging role of the KCNT1 Slack channel in intellectual disability.N-myristoylation regulates the axonal distribution of the Fragile X-related protein FXR2PMore than a pore: ion channel signaling complexesHuman slack potassium channel mutations increase positive cooperativity between individual channelsT-type Ca2+ channels are required for enhanced sympathetic axon growth by TNFα reverse signallingEffect of knockout of α2δ-1 on action potentials in mouse sensory neuronsCo-regulation of mRNA translation by TDP-43 and Fragile X Syndrome protein FMRPProteolytic maturation of α2δ represents a checkpoint for activation and neuronal trafficking of latent calcium channels.CaV2 channel subtype expression in rat sympathetic neurons is selectively regulated by α2δ subunits.New discoveries in schizophrenia genetics reveal neurobiological pathways: A review of recent findings.Molecular medicine of fragile X syndrome: based on known molecular mechanisms.Multifarious Functions of the Fragile X Mental Retardation Protein.Synaptic vesicle dynamic changes in a model of fragile X.Neuron class-specific requirements for Fragile X Mental Retardation Protein in critical period development of calcium signaling in learning and memory circuitry.Excitability is increased in hippocampal CA1 pyramidal cells of Fmr1 knockout mice.Stimulation of Slack K(+) Channels Alters Mass at the Plasma Membrane by Triggering Dissociation of a Phosphatase-Regulatory Complex.Altered synaptobrevin-II trafficking in neurons expressing a synaptophysin mutation associated with a severe neurodevelopmental disorder.Imbalance of synaptic actin dynamics as a key to the Fragile X syndrome?Axonal ribosomes and mRNAs associate with fragile X granules in adult rodent and human brains.Fragile X granules are a family of axonal ribonucleoprotein particles with circuit-dependent protein composition and mRNA cargos.Splice form-dependent regulation of axonal arbor complexity by FMRP.Fragile X mental retardation protein controls ion channel expression and activity.α-Actinin Anchors PSD-95 at Postsynaptic Sites.Genetic upregulation of BK channel activity normalizes multiple synaptic and circuit defects in a mouse model of fragile X syndrome.Of Men and Mice: Modeling the Fragile X Syndrome.Rare FMR1 gene mutations causing fragile X syndrome: A review.New Insights Into the Role of Ca2 Protein Family in Calcium Flux Deregulation in -KO Neurons
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Fragile X mental retardation protein controls synaptic vesicle exocytosis by modulating N-type calcium channel density
description
2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2014 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans Nature Communications
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artículu científicu espublizáu en 2014
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im April 2014 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2014/04/07)
@sk
vědecký článek publikovaný v roce 2014
@cs
wetenschappelijk artikel (gepubliceerd op 2014/04/07)
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наукова стаття, опублікована у квітні 2014
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name
Fragile X mental retardation p ...... N-type calcium channel density
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Fragile X mental retardation p ...... N-type calcium channel density
@en
Fragile X mental retardation p ...... N-type calcium channel density
@nl
type
label
Fragile X mental retardation p ...... N-type calcium channel density
@ast
Fragile X mental retardation p ...... N-type calcium channel density
@en
Fragile X mental retardation p ...... N-type calcium channel density
@nl
prefLabel
Fragile X mental retardation p ...... N-type calcium channel density
@ast
Fragile X mental retardation p ...... N-type calcium channel density
@en
Fragile X mental retardation p ...... N-type calcium channel density
@nl
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P1476
Fragile X mental retardation p ...... N-type calcium channel density
@en
P2093
John S Cassidy
Laurent Ferron
Manuela Nieto-Rostro
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P2888
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10.1038/NCOMMS4628
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P577
2014-04-07T00:00:00Z
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1024088898