Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
about
Ubiquitin signaling in immune responsesInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseCYLD Limits Lys63- and Met1-Linked Ubiquitin at Receptor Complexes to Regulate Innate Immune SignalingE3 Ubiquitin ligase ZNRF4 negatively regulates NOD2 signalling and induces tolerance to MDP.Reactive oxygen species regulate caspase-11 expression and activation of the non-canonical NLRP3 inflammasome during enteric pathogen infection.NOD1 and NOD2: signaling, host defense, and inflammatory disease.RIP kinases: key decision makers in cell death and innate immunity.Inhibition of lethal inflammatory responses through the targeting of membrane-associated Toll-like receptor 4 signaling complexes with a Smad6-derived peptide.Inflammatory Signaling by NOD-RIPK2 Is Inhibited by Clinically Relevant Type II Kinase Inhibitors.Nod2: The intestinal gate keeper.Receptor-Interacting Protein Kinase-2 Inhibition by CYLD Impairs Antibacterial Immune Responses in Macrophages.The role of NOD1 and NOD2 in host defense against chlamydial infection.The roles of Pellino E3 ubiquitin ligases in immunity.Met1-linked ubiquitination in immune signalling.Insights into the molecular basis of the NOD2 signalling pathway.Molecular and physiological roles of Pellino E3 ubiquitin ligases in immunity.E3 ubiquitin ligases Pellinos as regulators of pattern recognition receptor signaling and immune responses.Molecular mechanisms of regulation of Toll-like receptor signalingHow genetic testing can lead to targeted management of XIAP deficiency-related inflammatory bowel disease.Diverse ubiquitin linkages regulate RIP kinases-mediated inflammatory and cell death signaling.IL-36α expression is elevated in ulcerative colitis and promotes colonic inflammation.Chemotherapy-induced intestinal inflammatory responses are mediated by exosome secretion of double-strand DNA via AIM2 inflammasome activation.Variants in TRIM22 That Affect NOD2 Signaling Are Associated With Very-Early-Onset Inflammatory Bowel Disease.Posttranslational Modification Control of Inflammatory Signaling.The pellino e3 ubiquitin ligases recognize specific phosphothreonine motifs and have distinct substrate specificities.Nucleotide-binding oligomerization domain 1 and gastrointestinal disorders.Interferon gamma boosts the nucleotide oligomerization domain 2-mediated signaling pathway in human dendritic cells in an X-linked inhibitor of apoptosis protein and mammalian target of rapamycin-dependent manner.CARD3 deficiency protects against colitis through reduced epithelial cell apoptosis.NOD2 and inflammation: current insights.The E3 ubiquitin ligase Pellino2 mediates priming of the NLRP3 inflammasome.The deubiquitinase MYSM1 dampens NOD2-mediated inflammation and tissue damage by inactivating the RIP2 complex
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P2860
Pellino3 ubiquitinates RIP2 and mediates Nod2-induced signaling and protective effects in colitis
description
2013 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2013 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2013
@ast
im September 2013 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2013/09/01)
@sk
vědecký článek publikovaný v roce 2013
@cs
wetenschappelijk artikel (gepubliceerd op 2013/09/01)
@nl
наукова стаття, опублікована у вересні 2013
@uk
مقالة علمية (نشرت في سبتمبر 2013)
@ar
name
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@ast
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@en
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@nl
type
label
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@ast
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@en
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@nl
prefLabel
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@ast
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@en
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@nl
P2093
P2860
P50
P921
P3181
P356
P1433
P1476
Pellino3 ubiquitinates RIP2 an ...... protective effects in colitis
@en
P2093
Aoife Quinlan
Barry Hall
Fiachra Humphries
Gabriella Aviello
Paul N. Moynagh
Ronan Bergin
Ruaidhri Jackson
P2860
P304
P3181
P356
10.1038/NI.2669
P407
P50
P577
2013-09-01T00:00:00Z