Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
about
Increasing Adult Hippocampal Neurogenesis is Sufficient to Reduce Anxiety and Depression-Like BehaviorsBax and Bak function as the outer membrane component of the mitochondrial permeability pore in regulating necrotic cell death in miceRegulation of mitochondrial ceramide distribution by members of the BCL-2 familyBax regulates primary necrosis through mitochondrial dynamicsAssembly of Bak homodimers into higher order homooligomers in the mitochondrial apoptotic poreNIX is required for programmed mitochondrial clearance during reticulocyte maturationA stapled BIM peptide overcomes apoptotic resistance in hematologic cancers.Increasing adult hippocampal neurogenesis is sufficient to improve pattern separation.BAD-dependent regulation of fuel metabolism and K(ATP) channel activity confers resistance to epileptic seizures.Dysapoptosis of osteoblasts and osteocytes increases cancellous bone formation but exaggerates cortical porosity with age.Megakaryocytes possess a functional intrinsic apoptosis pathway that must be restrained to survive and produce platelets.Platelet production proceeds independently of the intrinsic and extrinsic apoptosis pathways.NMDA receptor-dependent LTD is required for consolidation but not acquisition of fear memory.Role of BH3-only molecules Bim and Puma in β-cell death in Pdx1 deficiencySuppression of skin and kidney disease by inhibition of spleen tyrosine kinase in lupus-prone miceApoptosis and the homeostatic control of immune responses.Antiapoptotic Mcl-1 is critical for the survival and niche-filling capacity of Foxp3⁺ regulatory T cellsBH3-only molecule Bim mediates β-cell death in IRS2 deficiency.Impact of bone marrow stromal cells on Bcl-2 family members in chronic lymphocytic leukemia.Bcl-2-regulated cell death signalling in the prevention of autoimmunity.Paclitaxel-induced apoptosis is BAK-dependent, but BAX and BIM-independent in breast tumor.Preferential killing of cancer cells with mitochondrial dysfunction by natural compounds.Epithelial cell death is an important contributor to oxidant-mediated acute lung injury.Tumor cells, but not endothelial cells, mediate eradication of primary sarcomas by stereotactic body radiation therapySignaling by the tumor necrosis factor receptor superfamily in B-cell biology and diseaseIn aged mice, low surrogate light chain promotes pro-B-cell apoptotic resistance, compromises the PreBCR checkpoint, and favors generation of autoreactive, phosphorylcholine-specific B cells.SCYL2 Protects CA3 Pyramidal Neurons from Excitotoxicity during Functional Maturation of the Mouse Hippocampus.Simultaneous deletion of Bax and Bak is required to prevent apoptosis and interstitial fibrosis in obstructive nephropathyAn interconnected hierarchical model of cell death regulation by the BCL-2 familyCommon variation at 6p21.31 (BAK1) influences the risk of chronic lymphocytic leukemiaMultiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.Aspm sustains postnatal cerebellar neurogenesis and medulloblastoma growth in mice.Localized hypoxia within the subgranular zone determines the early survival of newborn hippocampal granule cellsBcl-2-family proteins and hematologic malignancies: history and future prospects.B cell survival, surface BCR and BAFFR expression, CD74 metabolism, and CD8- dendritic cells require the intramembrane endopeptidase SPPL2A.BH3-only protein bid participates in the Bcl-2 network in healthy liver cellsApoptosis regulates ipRGC spacing necessary for rods and cones to drive circadian photoentrainment.Proapoptotic Bak and Bax guard against fatal systemic and organ-specific autoimmune diseaseDirect and selective small-molecule activation of proapoptotic BAXApoptosis in the development of the immune system.
P2860
Q27310639-07B230B8-13A6-4788-843C-50C1AAE4FB8CQ28297628-4771E46F-A530-464D-A460-3C2EE2CDA6D2Q28384330-2A4BCEB4-5A44-459E-94CF-D0FECBFB55D9Q28506109-3F016D47-B273-4972-A9A7-47DCBC809FB3Q28831381-1F80138B-CBF0-49D0-B330-4495B5D29FBFQ29614484-59647CD9-B3DA-4AA8-8E97-9B454F58D581Q30466831-3EFDBD5A-2FE8-4500-9C49-0CD1D3C16838Q30499942-03752CCF-6DD7-404B-9B1E-B222D705166CQ30514237-AA737489-0F5B-4F9D-9EC0-53B42A7DCE9CQ30557138-44FD294D-1B63-45F5-BC93-66177B2036F4Q33397149-5F8A46FE-478E-4479-A3C1-E8E744E76E17Q33413970-24A3039E-835E-4B58-8FE4-1D1E7BFB176BQ33801580-22735F7F-1028-4855-A949-236BE6D3075EQ33959699-80680655-F75E-4F1B-91F1-75BA52664876Q33987268-B34E9FA9-9359-4EA4-A408-CDB9CACDFB2BQ34023771-5F286111-9FE4-4B2A-A346-0D21EB8973E6Q34026357-C48DD242-8203-43FC-B55C-585F392D5330Q34227850-E6C9C803-8CBC-4D07-83B6-2EEEA520FCF7Q34231324-A183FD67-4436-4CDE-BCBA-D84C0433A7CAQ34545377-0B820651-1B78-460F-A8E3-4C389C62BD9FQ34663927-D1A7F3CB-8DF2-4E87-974B-47C9DF000483Q34891746-B3F668FF-0758-4F24-BFF6-30D185AB21D8Q34914561-93B363E9-DD1D-4D3A-8E52-2B22BDEC5654Q35178834-0F2F3D3C-13E2-46AC-AB22-B44F4EB6B98EQ35452032-B3E49CFD-D745-457A-8F48-E0D114768048Q35527180-4727A838-BD4A-4C0C-9FC7-4A8E0B423772Q35876812-2DD16C6E-7E38-4367-AE93-79CC40494E42Q36066400-E03F865B-2420-4AE0-BEEA-F821B4A4105AQ36109186-6AFDAFD0-A532-4490-83D1-6DEF62735B09Q36141922-787AC71C-21FD-40C9-BE7A-C42BF3B6ACDEQ36384731-B29C7D11-917A-4A0E-BA6A-7FB0442724AEQ36462666-CFFE42C1-50C2-4F1B-9BF3-2B13AD5E2DA3Q36468313-76C1FB22-7824-4254-B91A-5783982E0737Q36508817-29B53806-8B7F-4D83-8313-9C5E2586C98EQ36547677-453146F6-C390-4B7C-8718-296DBABD90A1Q36577830-6FE8D402-E8EF-49E8-BB9E-4A688C93895DQ36602415-43BB8C77-31FC-4D7B-932D-AE5DEA6BA339Q36616993-AC7A63D4-E817-491E-8D84-5FF7B6A657A6Q36741892-B5CE023F-4722-44B0-BA14-D1B23609B362Q36850158-B78D8DC6-B43E-424C-ADCE-5A35128F8627
P2860
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
description
2005 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2005
@ast
im August 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/08/09)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/08/09)
@nl
наукова стаття, опублікована в серпні 2005
@uk
name
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@ast
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@en
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@nl
type
label
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@ast
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@en
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@nl
prefLabel
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@ast
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@en
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@nl
P2093
P2860
P921
P3181
P356
P1476
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease
@en
P2093
Barbara A Malynn
Heikyung Suh
Hisashi Harada
Jill Fisher
Stanley J Korsmeyer
P2860
P304
11272-11277
P3181
P356
10.1073/PNAS.0504783102
P407
P50
P577
2005-07-29T00:00:00Z