The farnesoid X-receptor is an essential regulator of cholesterol homeostasis - Wikidata - wikimedia - TriplyDB

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

http://www.wikidata.org/entity/Q28513874

about

Peroxisome proliferator-activated receptor-gamma coactivator 1alpha (PGC-1alpha) regulates triglyceride metabolism by activation of the nuclear receptor FXR Lipidome in colorectal cancer Bile acids, obesity, and the metabolic syndrome Fatty liver diseases, bile acids, and FXR Bile Acid Nuclear Receptor Farnesoid X Receptor: Therapeutic Target for Nonalcoholic Fatty Liver Disease Bile acid nuclear receptor FXR and digestive system diseases Diacylglycerol kinase θ couples farnesoid X receptor-dependent bile acid signalling to Akt activation and glucose homoeostasis in hepatocytes Farnesoid X receptor regulates bile acid-amino acid conjugation Bile acid signaling in metabolic disease and drug therapy The orphan nuclear receptor LRH-1 activates the ABCG5/ABCG8 intergenic promoter Phospholipase D2 mediates signaling by ATPase class I type 8B membrane 1 The farnesoid X receptor modulates adiposity and peripheral insulin sensitivity in mice Farnesoid X receptor is essential for normal glucose homeostasis Ageing Fxr deficient mice develop increased energy expenditure, improved glucose control and liver damage resembling NASH FXR promotes endothelial cell motility through coordinated regulation of FAK and MMP-9.Linkage disequilibrium blocks, haplotype structure, and htSNPs of human CYP7A1 gene.Bile acid sequestrants for lipid and glucose control.Identification of novel pathways that control farnesoid X receptor-mediated hypocholesterolemia.New developments in selective cholesteryl ester uptake.Farnesoid X receptor activation mediates head-to-tail chromatin looping in the Nr0b2 gene encoding small heterodimer partner.Bile acid metabolites in serum: intraindividual variation and associations with coronary heart disease, metabolic syndrome and diabetes mellitus Protective effects of farnesoid X receptor (FXR) on hepatic lipid accumulation are mediated by hepatic FXR and independent of intestinal FGF15 signal Nutritional regulation of bile acid metabolism is associated with improved pathological characteristics of the metabolic syndrome.Diabetic nephropathy is accelerated by farnesoid X receptor deficiency and inhibited by farnesoid X receptor activation in a type 1 diabetes model Farnesoid X receptor induces murine scavenger receptor Class B type I via intron binding.Recent insights into farnesoid X receptor in non-alcoholic fatty liver disease.Functional characterization of the semisynthetic bile acid derivative INT-767, a dual farnesoid X receptor and TGR5 agonist.Tissue specific induction of p62/Sqstm1 by farnesoid X receptor.The extended TILAR approach: a novel tool for dynamic modeling of the transcription factor network regulating the adaption to in vitro cultivation of murine hepatocytes.Deciphering the nuclear bile acid receptor FXR paradigm.Tissue-specific function of farnesoid X receptor in liver and intestine Development of time resolved fluorescence resonance energy transfer-based assay for FXR antagonist discovery Studies in mice, hamsters, and rats demonstrate that repression of hepatic apoA-I expression by taurocholic acid in mice is not mediated by the farnesoid-X-receptor Melanocortin signaling in the CNS directly regulates circulating cholesterol.Farnesoid X receptor deficiency improves glucose homeostasis in mouse models of obesity.Increased activation of the Wnt/β-catenin pathway in spontaneous hepatocellular carcinoma observed in farnesoid X receptor knockout mice.MiR-22-silenced cyclin A expression in colon and liver cancer cells is regulated by bile acid receptor.Bile acids reduce endocytosis of high-density lipoprotein (HDL) in HepG2 cells.Effects of FXR in foam-cell formation and atherosclerosis development.Nuclear receptors in nonalcoholic Fatty liver disease

P2860

60069549546c458e6d5b65c986df4d6af33ffcf9 87ad89ee3304ded62f7070397b2bf2f5db605226

P248

Q24623871-D428E1D5-6E6F-46E8-9771-2B40361A9E05 Q26766296-B4C9BA30-C310-4991-B93A-F498D10D7FEE Q27020976-3CD3C59C-8766-4F51-816D-90B35C0C2B49 Q28068199-463388EC-1AD1-4273-B877-ED98553A1991 Q28076064-A45D2B25-3C54-4644-B9C9-1A0F51EB7189 Q28085493-6CD06A6A-DD79-476B-81D8-EFB494EF825C Q28114796-71DB4545-AF52-4BC5-A6EA-12123AB1C101 Q28204827-89CAD2CC-39FD-4D7D-9F56-A0695A06A2E4 Q28244875-E717D9E2-D365-468E-94B7-35735E62B826 Q28259634-D5B03BDA-8235-4561-A471-511CAAB9A4CC Q28395197-7AF8A82F-081B-48D7-8194-15BF12D445D6 Q28587753-213E96F7-8C8D-41C8-A307-3310A708C0E8 Q28591952-526EF845-65B7-4DA8-AD27-FFFD3ED1D884 Q30454451-9DF3B6AC-49B2-4054-BC59-D882A194461E Q30488268-1640C029-B26A-46F8-AC20-C66373C5389C Q33243916-588C0478-3CCC-4B2F-B2CE-118F50B56924 Q33651272-8BA94354-A881-49F6-B8DA-5D1AE9F4D48D Q33661459-CDE3A638-236F-4F99-848B-F5D99297640C Q33894679-950D1912-10F3-4418-9AD7-22A286112974 Q33993688-38D4E006-1261-47A7-9727-049C064DF8DA Q34081372-9C833327-9BDC-4BAC-B212-F37F253C5DEE Q34098522-BF8417F2-6794-4EDD-8202-DB97F574107A Q34193332-8DEC439C-AAD2-446B-A18D-BF778450D060 Q34237738-43200437-ECA8-4C08-90C5-A5259D4AE59D Q34249416-7D2BF1BD-CDE0-4701-ACE0-215396108867 Q34303001-9BC75F61-34C6-4DAB-83C8-9B63D73F1ADE Q34310071-A484C8D2-652D-4B53-B9D9-E24140B27B71 Q34405939-733F5B51-645A-429E-81EB-0A879BCF749B Q34494671-FF5ECD68-F84D-4FC0-970D-F7D20E8520BA Q34626518-05801637-821B-4DD4-930B-3B36ED25F9E1 Q34714107-BC8D5B74-466C-43A1-96CE-15D65F2E0B77 Q34729209-4BEACD18-E890-4B15-8C83-00249440E1AC Q34955918-D298EDD0-3F24-4734-9E6E-FC1139FF99C5 Q34999515-7AE915CD-27B6-43A5-BFAC-FCC89341D836 Q35063271-32756331-11E0-48A9-BBCD-76418D9757AB Q35077956-5F8F1D2D-5987-4154-AA8E-7E7024568CDA Q35173008-9AD76483-C65B-4227-AF3E-D54EEDB4E16B Q35204411-BC78C17F-356B-4E2B-AA85-AACE77AEBF9F Q35546179-04BC23AC-DB04-4C2F-8566-FF69155D43ED Q35609154-D1C28F4E-108F-4D8D-A142-81F9A11CB942

P2860

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

http://www.wikidata.org/entity/Q28513874

description

2003 թուականի Յունուարին հրատարակուած գիտական յօդուած

@hyw

2003 թվականի հունվարին հրատարակված գիտական հոդված

@hy

article publié dans la revue scientifique Journal of Biological Chemistry

@fr

artículu científicu espublizáu en 2003

@ast

im Januar 2003 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2003/01/24)

@sk

vědecký článek publikovaný v roce 2003

@cs

wetenschappelijk artikel (gepubliceerd op 2003/01/24)

@nl

наукова стаття, опублікована в січні 2003

@uk

name

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@ast

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@en

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@nl

type

label

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@ast

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@en

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@nl

prefLabel

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@ast

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@en

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@nl

P1433

Q28513874-96CA30E0-FA4F-4F5A-922A-6B75BEFB1CB4

P1476

Q28513874-AAE0646D-8233-4187-B043-B8D5E3361C2F

P2093

Q28513874-06CA1084-0597-44C4-9A52-505533B19B7D

Q28513874-414C3899-864C-4CE2-A175-456CEDA10DF7

Q28513874-43DEB17C-D345-41F4-AD81-42C1EF9649B4

Q28513874-96943FFD-BB16-46A3-A0A8-9989B72C3450

Q28513874-E32D9B24-443F-48E0-AF22-D72B51F15B69

P2860

Q28513874-02EC2CBE-C1D5-4527-AE2E-364A6CE843AE

Q28513874-0DCCB1A5-1DA2-4348-81F3-72BCCB8AD6C1

Q28513874-12B77E32-D576-4445-962C-6F2F1F03CD86

Q28513874-261A171A-FB98-4D6D-B38A-A0BD3AD0F711

Q28513874-283B7BD9-15AB-4745-A0D4-603AF282F4B1

Q28513874-30922F32-2B99-4EA4-B2A2-D5BA2D40D518

Q28513874-30C7871C-2912-4C61-9681-9301CEEEB234

Q28513874-3C1BFCED-5B5C-46B8-9CE7-6376F9B29BDC

Q28513874-4C450BA8-3839-4453-A5F7-F395C3084E1F

Q28513874-57687F8E-187B-4F37-96F1-0AEF82A048A3

P304

Q28513874-13D5D4C4-1897-409C-9FC8-1EB18B6F4BBA

P31

Q28513874-9C2CE494-984F-40DC-991E-12D4D0E9772F

P3181

Q28513874-E0E2109B-00C0-47FD-8AD2-FA2B0B7AF598

P356

Q28513874-A54DF87B-8A8C-4326-9D31-EBFD503C82B5

P407

Q28513874-3FAE3DA4-18E8-4CF1-B862-BDA8BCEE7353

P433

Q28513874-6C3C83F8-FD16-480A-81AB-D7D1B1A5CCF1

P478

Q28513874-939481F0-9B07-413A-A0BD-C97A31211286

P50

Q28513874-14C52A8A-4E30-4C03-8B9F-89B73DDD6CA4

P577

Q28513874-8F8A7E3F-A4DB-4628-9F20-4D3D413A40B9

P698

Q28513874-3B37E532-009F-40CD-8969-7DFE205CA831

P921

Q28513874-8684A1E2-30FC-403C-9FB6-FD8553D368E8

P3181

P356

P1433

Journal of Biological Chemistry

P1476

The farnesoid X-receptor is an essential regulator of cholesterol homeostasis

@en

P2093

Christopher J Sinal

http://www.w3.org/2001/XMLSchema#string

Frank J Gonzalez

http://www.w3.org/2001/XMLSchema#string

Grace Guo

http://www.w3.org/2001/XMLSchema#string

H Bryan Brewer

http://www.w3.org/2001/XMLSchema#string

Marcelo J A Amar

http://www.w3.org/2001/XMLSchema#string

P2860

Identification of a nuclear receptor for bile acids

Bile acids: natural ligands for an orphan nuclear receptor

Accumulation of dietary cholesterol in sitosterolemia caused by mutations in adjacent ABC transporters

The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity

A targeted mutation in the murine gene encoding the high density lipoprotein (HDL) receptor scavenger receptor class B type I reveals its key role in HDL metabolism

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

A PPAR gamma-LXR-ABCA1 pathway in macrophages is involved in cholesterol efflux and atherogenesis

Generation of multiple farnesoid-X-receptor isoforms through the use of alternative promoters

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

Evolution of the nuclear receptor superfamily: early diversification from an ancestral orphan receptor

P304

2563-2570

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P3181

4118120

http://www.w3.org/2001/XMLSchema#string

P356

10.1074/JBC.M209525200

http://www.w3.org/2001/XMLSchema#string

P407

P433

4

http://www.w3.org/2001/XMLSchema#string

P478

278

http://www.w3.org/2001/XMLSchema#string

P50

P577

2002-11-05T00:00:00Z

http://www.w3.org/2001/XMLSchema#dateTime

P698

12421815

http://www.w3.org/2001/XMLSchema#string

P921

Nuclear receptor subfamily 1, group H, member 4