A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis
about
The application of tetracyclineregulated gene expression systems in the validation of novel drug targets in Mycobacterium tuberculosisAspartate decarboxylase (PanD) as a new target of pyrazinamide in Mycobacterium tuberculosisThe tuberculosis drug discovery and development pipeline and emerging drug targets.In silico approaches and chemical space of anti-P-type ATPase compounds for discovering new antituberculous drugs.Advances in Drug Discovery and Development for Pediatric Tuberculosis.L-2,3-diaminopropionate generates diverse metabolic stresses in Salmonella enterica.Tuberculosis drug discovery and emerging targets.Future target-based drug discovery for tuberculosis?The future for early-stage tuberculosis drug discoveryThe Genome-Wide Interaction Network of Nutrient Stress Genes in Escherichia coli.Confirmation of a Protein-Protein Interaction in the Pantothenate Biosynthetic Pathway by Using Sortase-Mediated Labelling.Alanine mutation of the catalytic sites of Pantothenate Synthetase causes distinct conformational changes in the ATP binding region.High-Throughput Screening for Positive Allosteric Modulators Identified Potential Therapeutics against Acetylcholinesterase Inhibition.
P2860
Q26795478-3A5ECB8C-A4DB-486B-BC28-30D0C39BED0FQ34113610-DCCB7CA7-86F7-4D2A-8FCD-70F8D24D200EQ35664209-5A05164A-2BBF-4126-A611-A8DD9BE1759AQ36256916-6E70F62E-2350-42EE-91DD-BF5605B08B99Q37134041-9186F017-47D5-4DEA-ADEB-32E7744DAAA8Q37741953-362BBB6D-DB5C-4931-A052-9C620A7B157FQ38219605-F5811B73-2A55-4ECB-9C51-AF2428360C2AQ38280137-C0D43A9E-7151-4064-AD65-C8B91A626362Q38358621-337B05B2-7D23-4810-B113-252C2585DD11Q39159676-CE24F65A-519C-43F9-A992-8432450C8DDDQ48252468-07328E3B-B59E-4536-9164-C01B598F8606Q49449001-F8AFE426-3CC1-4D49-AA85-086961D86208Q53716874-9BE4A174-9E01-4EAB-9615-E0898C28C9C0
P2860
A high-throughput screen against pantothenate synthetase (PanC) identifies 3-biphenyl-4-cyanopyrrole-2-carboxylic acids as a new class of inhibitor with activity against Mycobacterium tuberculosis
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A high-throughput screen again ...... nst Mycobacterium tuberculosis
@ast
A high-throughput screen again ...... nst Mycobacterium tuberculosis
@en
A high-throughput screen again ...... nst Mycobacterium tuberculosis
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A high-throughput screen again ...... nst Mycobacterium tuberculosis
@ast
A high-throughput screen again ...... nst Mycobacterium tuberculosis
@en
A high-throughput screen again ...... nst Mycobacterium tuberculosis
@nl
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A high-throughput screen again ...... nst Mycobacterium tuberculosis
@ast
A high-throughput screen again ...... nst Mycobacterium tuberculosis
@en
A high-throughput screen again ...... nst Mycobacterium tuberculosis
@nl
P2093
P2860
P50
P1433
P1476
A high-throughput screen again ...... nst Mycobacterium tuberculosis
@en
P2093
Allen Casey
Anuradha Kumar
David R Sherman
Edward A Kesicki
Joshua Odingo
Michal Vieth
Philip A Hipskind
Thierry Masquelin
P2860
P304
P356
10.1371/JOURNAL.PONE.0072786
P407
P577
2013-01-01T00:00:00Z