An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression
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Advances in lupus geneticsCapture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23Genetics of systemic lupus erythematosus: immune responses and end organ resistance to damage.Hypomorphic A20 expression confers susceptibility to psoriasis.Advances in lupus genetics and epigeneticsEnhancer variants: evaluating functions in common disease.Association between TNFAIP3 nonsynonymous single-nucleotide polymorphism rs2230926 and chronic hepatitis B virus infection in a Chinese Han population.Let-7 miRNAs Modulate the Activation of NF-κB by Targeting TNFAIP3 and Are Involved in the Pathogenesis of Lupus Nephritis.Immunogenetics of systemic lupus erythematosus: A comprehensive review.Recruitment of A20 by the C-terminal domain of NEMO suppresses NF-κB activation and autoinflammatory disease.Significant lethality following liver resection in A20 heterozygous knockout mice uncovers a key role for A20 in liver regenerationTALEN-mediated enhancer knockout influences TNFAIP3 gene expression and mimics a molecular phenotype associated with systemic lupus erythematosus.Context-dependent cooperation between nuclear factor κB (NF-κB) and the glucocorticoid receptor at a TNFAIP3 intronic enhancer: a mechanism to maintain negative feedback control of inflammation.Genetics and pathogenesis of systemic lupus erythematosus and lupus nephritis.Roles of A20 in autoimmune diseases.Post-translational control of NF-κB signaling by ubiquitination.The genetics revolution in rheumatology: large scale genomic arrays and genetic mapping.Single nucleotide polymorphisms of TNFAIP3 are associated with systemic lupus erythematosus in Han Chinese population.Association of the tandem polymorphisms (rs148314165, rs200820567) in TNFAIP3 with chronic hepatitis B virus infection in Chinese Han population.A functional variant in the OAS1 gene is associated with Sjögren's syndrome complicated with HBV infection.Updates in Lupus Genetics.Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.An Autoimmune Disease-Associated Risk Variant in the TNFAIP3 Gene Plays a Protective Role in Brucellosis That Is Mediated by the NF-κB Signaling Pathway.TNFAIP3 downregulation mediated by histone modification contributes to T-cell dysfunction in systemic lupus erythematosus.Aberrant Low Expression of A20 in Tumor Necrosis Factor-α-stimulated SLE Monocytes Mediates Sustained NF-κB Inflammatory Response.From association to mechanism in complex disease genetics: the role of the 3D genomeThe interleukin-27 -964A>G polymorphism enhances sepsis-induced inflammatory responses and confers susceptibility to the development of sepsis
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P2860
An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression
description
2013 nî lūn-bûn
@nan
2013 թուականին հրատարակուած գիտական յօդուած
@hyw
2013 թվականին հրատարակված գիտական հոդված
@hy
2013年の論文
@ja
2013年論文
@yue
2013年論文
@zh-hant
2013年論文
@zh-hk
2013年論文
@zh-mo
2013年論文
@zh-tw
2013年论文
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name
An enhancer element harboring ...... er to influence A20 expression
@ast
An enhancer element harboring ...... er to influence A20 expression
@en
An enhancer element harboring ...... er to influence A20 expression
@nl
type
label
An enhancer element harboring ...... er to influence A20 expression
@ast
An enhancer element harboring ...... er to influence A20 expression
@en
An enhancer element harboring ...... er to influence A20 expression
@nl
prefLabel
An enhancer element harboring ...... er to influence A20 expression
@ast
An enhancer element harboring ...... er to influence A20 expression
@en
An enhancer element harboring ...... er to influence A20 expression
@nl
P2093
P2860
P3181
P1433
P1476
An enhancer element harboring ...... er to influence A20 expression
@en
P2093
Graham B Wiley
Shaofeng Wang
P2860
P304
P3181
P356
10.1371/JOURNAL.PGEN.1003750
P407
P577
2013-09-05T00:00:00Z