Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.

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Dissection and function of autoimmunity-associated TNFAIP3 (A20) gene enhancers in humanized mouse models.

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2018 nî lūn-bûn

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2018年の論文

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年学术文章

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2018年學術文章

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2018年學術文章

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name

Dissection and function of aut ...... ers in humanized mouse models.

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Dissection and function of autoimmunity-associated TNFAIP3

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label

Dissection and function of aut ...... ers in humanized mouse models.

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Dissection and function of autoimmunity-associated TNFAIP3

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Dissection and function of aut ...... ers in humanized mouse models.

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Dissection and function of autoimmunity-associated TNFAIP3

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P1476

Dissection and function of aut ...... cers in humanized mouse models

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P2093

Baohong Zhao

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Laura Frye

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Mark P Liber

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Rada Norinsky

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Shiaoching Gong

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Sungho Park

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Tania Pannellini

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P2860

Species-specific transcription in mice carrying human chromosome 21

Failure to regulate TNF-induced NF-kappaB and cell death responses in A20-deficient mice

Control of cell identity genes occurs in insulated neighborhoods in mammalian chromosomes

Genetic Control of Chromatin States in Humans Involves Local and Distal Chromosomal Interactions

An enhancer element harboring variants associated with systemic lupus erythematosus engages the TNFAIP3 promoter to influence A20 expression

B cells lacking the tumor suppressor TNFAIP3/A20 display impaired differentiation and hyperactivation and cause inflammation and autoimmunity in aged mice

BCL11A enhancer dissection by Cas9-mediated in situ saturating mutagenesis

Genetic and epigenetic fine mapping of causal autoimmune disease variants

Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosus

Systematic localization of common disease-associated variation in regulatory DNA

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s41467-018-03081-7

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658

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scholarly article

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10.1038/S41467-018-03081-7

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English

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P478

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Upneet K Sokhi

Lionel B Ivashkiv

Kyuho Kang

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2018-02-13T00:00:00Z

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1100901767

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29440643

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5811492

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