MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms
about
Non-homologous isofunctional enzymes: a systematic analysis of alternative solutions in enzyme evolution.Identification of NAD interacting residues in proteinsOn the origin of life in the Zinc world. 2. Validation of the hypothesis on the photosynthesizing zinc sulfide edifices as cradles of life on EarthUse of anion-aromatic interactions to position the general base in the ketosteroid isomerase active siteMACiE: exploring the diversity of biochemical reactionsEvolutionarily conserved substrate substructures for automated annotation of enzyme superfamiliesQuantitative comparison of catalytic mechanisms and overall reactions in convergently evolved enzymes: implications for classification of enzyme functionAssignment of EC numbers to enzymatic reactions with reaction difference fingerprintsThe natural history of biocatalytic mechanismsFrom sequence to enzyme mechanism using multi-label machine learning.Exploring the structure and function paradigm.Prediction and experimental validation of enzyme substrate specificity in protein structures.The rough guide to in silico function prediction, or how to use sequence and structure information to predict protein function.EnzyMiner: automatic identification of protein level mutations and their impact on target enzymes from PubMed abstractsThe acid-base profile of a contemporary set of drugs: implications for drug discovery.The CoFactor database: organic cofactors in enzyme catalysis.Exploring the evolution of novel enzyme functions within structurally defined protein superfamilies.Is EC class predictable from reaction mechanism?Quantum mechanics/molecular mechanics investigation of the mechanism of phosphate transfer in human uridine-cytidine kinase 2.Genome and proteome annotation: organization, interpretation and integration.Rapid catalytic template searching as an enzyme function prediction procedure.Rhea--a manually curated resource of biochemical reactionsInference of functional properties from large-scale analysis of enzyme superfamilies.Novel Computational Protocols for Functionally Classifying and Characterising Serine Beta-Lactamases.Informatics, machine learning and computational medicinal chemistry.Toward mechanistic classification of enzyme functions.Characterizing the complexity of enzymes on the basis of their mechanisms and structures with a bio-computational analysis.Enzyme informatics.CATH-Gene3D: Generation of the Resource and Its Use in Obtaining Structural and Functional Annotations for Protein Sequences.FunTree: a resource for exploring the functional evolution of structurally defined enzyme superfamilies.Enzyme mechanism prediction: a template matching problem on InterPro signature subspaces.Why do Sequence Signatures Predict Enzyme Mechanism? Homology versus Chemistry.Catalytic residues in hydrolases: analysis of methods designed for ligand-binding site prediction.CSmetaPred: a consensus method for prediction of catalytic residues.Mechanism and Catalytic Site Atlas (M-CSA): a database of enzyme reaction mechanisms and active sites.The NAD Binding Domain and the Short-Chain Dehydrogenase/Reductase (SDR) Superfamily
P2860
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P2860
MACiE (Mechanism, Annotation and Classification in Enzymes): novel tools for searching catalytic mechanisms
description
2007 nî lūn-bûn
@nan
2007 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2007年の論文
@ja
2007年論文
@yue
2007年論文
@zh-hant
2007年論文
@zh-hk
2007年論文
@zh-mo
2007年論文
@zh-tw
2007年论文
@wuu
name
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@ast
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@en
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@nl
type
label
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@ast
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@en
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@nl
prefLabel
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@ast
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@en
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@nl
P2860
P50
P3181
P356
P1476
MACiE (Mechanism, Annotation a ...... searching catalytic mechanisms
@en
P2093
Gail J Bartlett
James W Torrance
P2860
P304
P3181
P356
10.1093/NAR/GKL774
P407
P433
Database issue
P50
P577
2006-11-01T00:00:00Z