Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activation
about
Differential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cellsMatriptase and prostasin are expressed in human skin in an inverse trend over the course of differentiation and are targeted to different regions of the plasma membrane.Interaction exists between matriptase inhibitors and intestinal epithelial cells.Matriptase shedding is closely coupled with matriptase zymogen activation and requires de novo proteolytic cleavage likely involving its own activity.Tissue distribution and subcellular localizations determine in vivo functional relationship among prostasin, matriptase, HAI-1, and HAI-2 in human skin.
P2860
Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activation
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2014 թուականին հրատարակուած գիտական յօդուած
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2014 թվականին հրատարակված գիտական հոդված
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2014年の論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年論文
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2014年论文
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Human cancer cells retain mode ...... nduction of zymogen activation
@ast
Human cancer cells retain mode ...... nduction of zymogen activation
@en
Human cancer cells retain mode ...... nduction of zymogen activation
@nl
type
label
Human cancer cells retain mode ...... nduction of zymogen activation
@ast
Human cancer cells retain mode ...... nduction of zymogen activation
@en
Human cancer cells retain mode ...... nduction of zymogen activation
@nl
prefLabel
Human cancer cells retain mode ...... nduction of zymogen activation
@ast
Human cancer cells retain mode ...... nduction of zymogen activation
@en
Human cancer cells retain mode ...... nduction of zymogen activation
@nl
P2093
P2860
P3181
P1433
P1476
Human cancer cells retain mode ...... nduction of zymogen activation
@en
P2093
Chen-Yong Lin
Chun-Che Tseng
Hong-Yu Lai
Hsiang-Hua Chang
Hue-Yu Wang
Jehng-Kang Wang
Jie-Ru Yang
Li-Ling Chu
Michael D Johnson
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0092244
P407
P577
2014-01-01T00:00:00Z