Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts
about
Human cancer cells retain modest levels of enzymatically active matriptase only in extracellular milieu following induction of zymogen activationMatriptase autoactivation is tightly regulated by the cellular chemical environmentsEvidence for the occurrence of membrane-type serine protease 1/matriptase on the basolateral sides of enterocytesMatriptase activation, an early cellular response to acidosis.Matriptase: potent proteolysis on the cell surface.Detection of active matriptase using a biotinylated chloromethyl ketone peptideDifferential subcellular localization renders HAI-2 a matriptase inhibitor in breast cancer cells but not in mammary epithelial cellsPurification from human milk of matriptase complexes with secreted serpins: mechanism for inhibition of matriptase other than HAI-1.The cutting edge: membrane-anchored serine protease activities in the pericellular microenvironment.Polarized epithelial cells secrete matriptase as a consequence of zymogen activation and HAI-1-mediated inhibition.Matriptase regulates proliferation and early, but not terminal, differentiation of human keratinocytesAutoactivation of matriptase in vitro: requirement for biomembrane and LDL receptor domain.HAI-1 regulates activation and expression of matriptase, a membrane-bound serine protease.Simultaneous activation and hepatocyte growth factor activator inhibitor 1-mediated inhibition of matriptase induced at activation foci in human mammary epithelial cells.Alpha1-antitrypsin inhibits the activity of the matriptase catalytic domain in vitro.The type II transmembrane serine protease matriptase cleaves the amyloid precursor protein and reduces its processing to β amyloid.Matriptase activation and shedding with HAI-1 is induced by steroid sex hormones in human prostate cancer cells, but not in breast cancer cells.Inflammatory cytokines down-regulate the barrier-protective prostasin-matriptase proteolytic cascade early in experimental colitis.Expression of matriptase correlates with tumour progression and clinical prognosis in oral squamous cell carcinoma.
P2860
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P2860
Assembly of adherens junctions is required for sphingosine 1-phosphate-induced matriptase accumulation and activation at mammary epithelial cell-cell contacts
description
2004 nî lūn-bûn
@nan
2004 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2004年の論文
@ja
2004年論文
@yue
2004年論文
@zh-hant
2004年論文
@zh-hk
2004年論文
@zh-mo
2004年論文
@zh-tw
2004年论文
@wuu
name
Assembly of adherens junctions ...... epithelial cell-cell contacts
@ast
Assembly of adherens junctions ...... epithelial cell-cell contacts
@en
Assembly of adherens junctions ...... epithelial cell-cell contacts
@nl
type
label
Assembly of adherens junctions ...... epithelial cell-cell contacts
@ast
Assembly of adherens junctions ...... epithelial cell-cell contacts
@en
Assembly of adherens junctions ...... epithelial cell-cell contacts
@nl
prefLabel
Assembly of adherens junctions ...... epithelial cell-cell contacts
@ast
Assembly of adherens junctions ...... epithelial cell-cell contacts
@en
Assembly of adherens junctions ...... epithelial cell-cell contacts
@nl
P2093
P2860
P1476
Assembly of adherens junctions ...... epithelial cell-cell contacts
@en
P2093
Chen-Yong Lin
Cicely A Williams
Ia-Wen J Hsu
Jennifer L Dreiling
Michael D Oberst
Mon-Juan Lee
Robert B Dickson
Ruei-Jiun Hung
P2860
P304
P356
10.1152/AJPCELL.00400.2003
P407
P577
2004-05-01T00:00:00Z