Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation

Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation

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http://www.wikidata.org/entity/Q28544916
Learning from the past for TB drug discovery in the futureTHPP target assignment reveals EchA6 as an essential fatty acid shuttle in mycobacteriaCombining Metabolite-Based Pharmacophores with Bayesian Machine Learning Models for Mycobacterium tuberculosis Drug DiscoveryHow Reliable Are Ligand-Centric Methods for Target Fishing?Inhibiting mycobacterial tryptophan synthase by targeting the inter-subunit interface.Mycobacterial cell wall biosynthesis: a multifaceted antibiotic target.Polypharmacology: in silico methods of ligand design and development.Collaborative drug discovery for More Medicines for Tuberculosis (MM4TB).A Systems Biology Approach for Identifying Hepatotoxicant Groups Based on Similarity in Mechanisms of Action and Chemical Structure.Predicting the Reliability of Drug-target Interaction Predictions with Maximum Coverage of Target Space.Target Identification of Mycobacterium tuberculosis Phenotypic Hits Using a Concerted Chemogenomic, Biophysical, and Structural Approach.Beyond the hype: deep neural networks outperform established methods using a ChEMBL bioactivity benchmark set.dfrA thyA Double Deletion in para-Aminosalicylic Acid-Resistant Mycobacterium tuberculosis Beijing Strains.Antimycobacterial drug discovery using Mycobacteria-infected amoebae identifies anti-infectives and new molecular targets.
P2860

Mycobacterial dihydrofolate reductase inhibitors identified using chemogenomic methods and in vitro validation

Item
http://www.wikidata.org/entity/Q28544916
description
2015 nî lūn-bûn
@nan
2015 թուականին հրատարակուած գիտական յօդուած
@hyw
2015 թվականին հրատարակված գիտական հոդված
@hy
2015年の論文
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2015年論文
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2015年論文
@zh-hant
2015年論文
@zh-hk
2015年論文
@zh-mo
2015年論文
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2015年论文
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name
Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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Mycobacterial dihydrofolate re ...... ethods and in vitro validation
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P2093
P2860
P304
P31
P3181
P356
10.1371/JOURNAL.PONE.0121492
P407
P433
P478
P50
P577
P5875
P698
P932