Gain and loss of channel function by alanine substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor
about
Polar residues in the second transmembrane domain of the rat P2X2 receptor that affect spontaneous gating, unitary conductance, and rectificationRegulation of ATP-gated P2X channels: from redox signaling to interactions with other proteinsPore-opening mechanism in trimeric P2X receptor channelsIdentification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains.Structural insights into the function of P2X4: an ATP-gated cation channel of neuroendocrine cells.Multiple roles of the extracellular vestibule amino acid residues in the function of the rat P2X4 receptor.Functional identification of close proximity amino acid side chains within the transmembrane-spanning helixes of the P2X2 receptorThe mechanism by which ethanol inhibits rat P2X4 receptors is altered by mutation of histidine 241.Activation and regulation of purinergic P2X receptor channelsPrenatal expression of purinergic receptor P2X3 in human dorsal root ganglionSecondary structure and gating rearrangements of transmembrane segments in rat P2X4 receptor channels.Photo-switchable tweezers illuminate pore-opening motions of an ATP-gated P2X ion channelAllosteric modulation of ATP-gated P2X receptor channelsGating the pore of P2X receptor channelsOptical control of an ion channel gateStructural and functional properties of the rat P2X4 purinoreceptor extracellular vestibule during gating.Key sites for P2X receptor function and multimerization: overview of mutagenesis studies on a structural basis.Highly conserved tyrosine 37 stabilizes desensitized states and restricts calcium permeability of ATP-gated P2X3 receptor.Functional relevance of aromatic residues in the first transmembrane domain of P2X receptors.On the role of the first transmembrane domain in cation permeability and flux of the ATP-gated P2X2 receptor.Participation of the Lys313-Ile333 sequence of the purinergic P2X4 receptor in agonist binding and transduction of signals to the channel gate.Functional characterization of mutants in the transmembrane domains of the rat P2X7 receptor that regulate pore conductivity and agonist sensitivity.Functional and structural identification of amino acid residues of the P2X2 receptor channel critical for the voltage- and [ATP]-dependent gating.
P2860
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P2860
Gain and loss of channel function by alanine substitutions in the transmembrane segments of the rat ATP-gated P2X2 receptor
description
2004 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im August 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/08/18)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/08/18)
@nl
наукова стаття, опублікована в серпні 2004
@uk
مقالة علمية (نشرت في 18-8-2004)
@ar
name
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@ast
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@en
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@nl
type
label
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@ast
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@en
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@nl
prefLabel
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@ast
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@en
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@nl
P2093
P1476
Gain and loss of channel funct ...... he rat ATP-gated P2X2 receptor
@en
P2093
Damien S K Samways
Keisuke Migita
Mark M Voigt
Terrance M Egan
Zhiyuan Li
P304
P356
10.1523/JNEUROSCI.1423-04.2004
P407
P577
2004-08-01T00:00:00Z