Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway
about
Hairy-related transcription factors inhibit Notch-induced smooth muscle alpha-actin expression by interfering with Notch intracellular domain/CBF-1 complex interaction with the CBF-1-binding siteImpact of notch signaling on inflammatory responses in cardiovascular disordersPerivascular delivery of Notch 1 siRNA inhibits injury-induced arterial remodelingThe role of notch in the cardiovascular system: potential adverse effects of investigational notch inhibitorsEndothelial expression of the Notch ligand Jagged1 is required for vascular smooth muscle developmentActivation of Notch3 promotes pulmonary arterial smooth muscle cells proliferation via Hes1/p27Kip1 signaling pathwayBiochemical characterization and cellular effects of CADASIL mutants of NOTCH3Glycogen synthase kinase 3 beta positively regulates Notch signaling in vascular smooth muscle cells: role in cell proliferation and survivalSmooth muscle cell-specific Notch1 haploinsufficiency restricts the progression of abdominal aortic aneurysm by modulating CTGF expression.Notch and transforming growth factor-beta (TGFbeta) signaling pathways cooperatively regulate vascular smooth muscle cell differentiation.Notch3 is critical for proper angiogenesis and mural cell investment.Differential expression of Hedgehog/Notch and transforming growth factor-β in human abdominal aortic aneurysms.Mir-206 regulates pulmonary artery smooth muscle cell proliferation and differentiationNotch3 and HEY-1 as prognostic biomarkers in pancreatic adenocarcinoma.Notch signaling change in pulmonary vascular remodeling in rats with pulmonary hypertension and its implication for therapeutic intervention.Notch signaling in descending thoracic aortic aneurysm and dissectionEthanol stimulates endothelial cell angiogenic activity via a Notch- and angiopoietin-1-dependent pathway.An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.Von Willebrand factor inhibits mature smooth muscle gene expression through impairment of Notch signaling.Activation dynamics and signaling properties of Notch3 receptor in the developing pulmonary artery.Age-related Notch-4 quiescence is associated with altered wall remodeling during vein graft adaptationFunctional analysis of a recurrent missense mutation in Notch3 in CADASILInvestigational Notch and Hedgehog inhibitors--therapies for cardiovascular disease.Alcohol and cardiovascular disease--modulation of vascular cell function.Alcohol inhibits smooth muscle cell proliferation via regulation of the Notch signaling pathwayEthanol inhibits γ-secretase proteolytic activity in vascular smooth muscle cells.MicroRNAs in pulmonary arterial remodelingSmooth muscle Notch1 mediates neointimal formation after vascular injury.Notch3 establishes brain vascular integrity by regulating pericyte number.Sonic Hedgehog induces Notch target gene expression in vascular smooth muscle cells via VEGF-AInhibition of patched-1 prevents injury-induced neointimal hyperplasia.Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells?The Notch pathway: a novel target for myocardial remodelling therapy?Hedgehog and Resident Vascular Stem Cell Fate.Notch Signaling in Vascular Smooth Muscle Cells.YB-1 acts as a ligand for Notch-3 receptors and modulates receptor activation.Differential Regulation of NOTCH2 and NOTCH3 Contribute to Their Unique Functions in Vascular Smooth Muscle Cells.Mechanisms of Smooth Muscle Cell Differentiation Are Distinctly Altered in Thoracic Aortic Aneurysms Associated with Bicuspid or Tricuspid Aortic ValvesThe benefit of docosahexanoic acid on the migration of vascular smooth muscle cells is partially dependent on Notch regulation of MMP-2/-9.RNA interference-mediated NOTCH3 knockdown induces phenotype switching of vascular smooth muscle cells in vitro.
P2860
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P2860
Notch 1 and 3 receptor signaling modulates vascular smooth muscle cell growth, apoptosis, and migration via a CBF-1/RBP-Jk dependent pathway
description
2004 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im September 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/09/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/09/01)
@nl
наукова стаття, опублікована у вересні 2004
@uk
مقالة علمية (نشرت في سبتمبر 2004)
@ar
name
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@ast
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@en
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@nl
type
label
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@ast
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@en
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@nl
prefLabel
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@ast
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@en
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@nl
P2093
P50
P356
P1433
P1476
Notch 1 and 3 receptor signali ...... CBF-1/RBP-Jk dependent pathway
@en
P2093
Agnieszka Scheller
Catherine Sweeney
Colm Hennessy
David Morrow
Philip M Cummins
Yvonne A Birney
P304
P356
10.1096/FJ.04-1700FJE
P407
P577
2004-07-09T00:00:00Z