Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart
about
Cardiac cyclic nucleotide phosphodiesterases: function, regulation, and therapeutic prospects.Effects of proarrhythmic drugs on relaxation time and beating pattern in rat engineered heart tissue.Differential regulation of β2 -adrenoceptor-mediated inotropic and lusitropic response by PDE3 and PDE4 in failing and non-failing rat cardiac ventricle.Conserved expression and functions of PDE4 in rodent and human heart.Epinephrine reversed high-concentration bupivacaine-induced inhibition of calcium channels and transient outward potassium current channels, but not on sodium channel in ventricular myocytes of rats.Interaction between phosphodiesterases in the regulation of the cardiac β-adrenergic pathway.Ontogenic changes of the control by phosphodiesterase-3 and -4 of 5-HT responses in porcine heart and relevance to human atrial 5-HT(4) receptors.β 1 Adrenoceptor antagonistic effects of the supposedly selective β 2 adrenoceptor antagonist ICI 118,551 on the positive inotropic effect of adrenaline in murine hearts.Differential regulation of cardiac excitation-contraction coupling by cAMP phosphodiesterase subtypes.PDE3, but not PDE4, reduces β₁ - and β₂-adrenoceptor-mediated inotropic and lusitropic effects in failing ventricle from metoprolol-treated patients.Inhibitors of phosphodiesterases PDE2, PDE3, and PDE4 do not increase the sinoatrial tachycardia of noradrenaline and prostaglandin PGE₁ in mice.Phosphodiesterase-4 activity: a critical modulator of atrial contractility and arrhythmogenesis.Increased spontaneous activity and reduced inotropic response to catecholamines in ventricular myocytes from footshock-stressed rats.Cardiac PDEs and crosstalk between cAMP and cGMP signalling pathways in the regulation of contractility.Functional β2-adrenoceptors in rat left atria: effect of foot-shock stress.
P2860
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P2860
Inotropy and L-type Ca2+ current, activated by beta1- and beta2-adrenoceptors, are differently controlled by phosphodiesterases 3 and 4 in rat heart
description
2009 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի հունվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im Januar 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/01/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/01/01)
@nl
наукова стаття, опублікована в січні 2009
@uk
مقالة علمية (نشرت عام 2009)
@ar
name
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@ast
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@en
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@nl
type
label
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@ast
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@en
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@nl
prefLabel
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@ast
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@en
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@nl
P2093
P2860
P1476
Inotropy and L-type Ca2+ curre ...... esterases 3 and 4 in rat heart
@en
P2093
Alberto J Kaumann
Marcus Thoms
Torsten Christ
Ursula Ravens
P2860
P356
10.1111/J.1476-5381.2008.00015.X
P407
P577
2009-01-01T00:00:00Z