CTP:phosphocholine cytidylyltransferase alpha is a cytosolic protein in pulmonary epithelial cells and tissues
about
Caspase processing and nuclear export of CTP:phosphocholine cytidylyltransferase alpha during farnesol-induced apoptosis.Surfactant phospholipid metabolismF-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrestDisruption of CCTbeta2 expression leads to gonadal dysfunction.Functions of membrane binding domain of CTP:phosphocholine cytidylyltransferase in alveolar type II cellsMalonyl-CoA decarboxylase is present in the cytosolic, mitochondrial and peroxisomal compartments of rat hepatocytesBoth acidic and basic amino acids in an amphitropic enzyme, CTP:phosphocholine cytidylyltransferase, dictate its selectivity for anionic membranesCalmodulin binds and stabilizes the regulatory enzyme, CTP: phosphocholine cytidylyltransferaseSurfactant lipid synthesis and lamellar body formation in glycogen-laden type II cellsExpansion of the nucleoplasmic reticulum requires the coordinated activity of lamins and CTP:phosphocholine cytidylyltransferase alpha.Nuclear export of the rate-limiting enzyme in phosphatidylcholine synthesis is mediated by its membrane binding domain.Increased phosphatidylcholine production but disrupted glycogen metabolism in fetal type II cells of mice that overexpress CTP:phosphocholine cytidylyltransferase.14-3-3zeta escorts CCTalpha for calcium-activated nuclear import in lung epithelia.Using protein microarray technology to screen anti-ERCC1 monoclonal antibodies for specificity and applications in pathologyRole of phosphocholine cytidylyltransferase alpha in lung development.Membrane phospholipid synthesis and endoplasmic reticulum function.Oxidized lipoproteins inhibit surfactant phosphatidylcholine synthesis via calpain-mediated cleavage of CTP:phosphocholine cytidylyltransferase.Mutations in PCYT1A, encoding a key regulator of phosphatidylcholine metabolism, cause spondylometaphyseal dysplasia with cone-rod dystrophy.The role of phosphatidylcholine and choline metabolites to cell proliferation and survival.Mechanistic insights into the nongenomic regulation of phospholipid synthesizing enzymes.Phosphatidylcholine: Greasing the Cholesterol Transport Machinery.The major sites of cellular phospholipid synthesis and molecular determinants of Fatty Acid and lipid head group specificity.15-deoxy-Delta12,14-prostaglandin J2 impairs phosphatidylcholine synthesis and induces nuclear accumulation of thiol-modified cytidylyltransferaseProapoptotic effects of P. aeruginosa involve inhibition of surfactant phosphatidylcholine synthesis.Upregulation of surfactant synthesis triggers ABCA1-mediated basolateral phospholipid efflux.Induction of apoptosis by lipophilic activators of CTP:phosphocholine cytidylyltransferase alpha (CCTalpha).The intrinsically disordered nuclear localization signal and phosphorylation segments distinguish the membrane affinity of two cytidylyltransferase isoforms.Contribution of each membrane binding domain of the CTP:phosphocholine cytidylyltransferase-alpha dimer to its activation, membrane binding, and membrane cross-bridging.Phosphatidylcholine biosynthesis via CTP:phosphocholine cytidylyltransferase 2 facilitates neurite outgrowth and branching.Differential Targets and Subcellular Localization of Antitumor Alkyl-lysophospholipid in LeukemicVersusSolid Tumor CellsHypoxia-Inducible Factor 2α Plays a Critical Role in the Formation of Alveoli and Surfactant
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P2860
CTP:phosphocholine cytidylyltransferase alpha is a cytosolic protein in pulmonary epithelial cells and tissues
description
2001 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Dezember 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/12/28)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/12/28)
@nl
наукова стаття, опублікована в грудні 2001
@uk
name
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@ast
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@en
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@nl
type
label
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@ast
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@en
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@nl
prefLabel
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@ast
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@en
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@nl
P2093
P356
P1476
CTP:phosphocholine cytidylyltr ...... y epithelial cells and tissues
@en
P2093
P304
49148–49155
P356
10.1074/JBC.M103566200
P407
P577
2001-12-28T00:00:00Z