Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis
about
Replacement of retinyl esters by polyunsaturated triacylglycerol species in lipid droplets of hepatic stellate cells during activationIntestine-specific expression of acyl CoA:diacylglycerol acyltransferase 1 reverses resistance to diet-induced hepatic steatosis and obesity in Dgat1-/- miceHepatic fibrosis.Recovery from liver disease in a Niemann-Pick type C mouse model.Increased diacylglycerols characterize hepatic lipid changes in progression of human nonalcoholic fatty liver disease; comparison to a murine modelInterleukin-1 as an injury signal mobilizes retinyl esters in hepatic stellate cells through down regulation of lecithin retinol acyltransferase.Vitamin A metabolism: an update.Hepatic stellate cell lipid droplets: a specialized lipid droplet for retinoid storage.Thematic review series: glycerolipids. DGAT enzymes and triacylglycerol biosynthesis.Monocyte chemoattractant protein-1 deficiency does not affect steatosis or inflammation in livers of mice fed a methionine-choline-deficient dietSpecific role for acyl CoA:Diacylglycerol acyltransferase 1 (Dgat1) in hepatic steatosis due to exogenous fatty acids.S-Adenosylmethionine increases circulating very-low density lipoprotein clearance in non-alcoholic fatty liver disease.DGAT1-deficiency affects the cellular distribution of hepatic retinoid and attenuates the progression of CCl4-induced liver fibrosis.Increased hepatic synthesis and dysregulation of cholesterol metabolism is associated with the severity of nonalcoholic fatty liver disease.Obstructive sleep apnea and non-alcoholic Fatty liver disease: is the liver another target?Hepatic metabolism of retinoids and disease associationsATGL and DGAT1 are involved in the turnover of newly synthesized triacylglycerols in hepatic stellate cellsMicroRNA expression profile in Lieber-DeCarli diet-induced alcoholic and methionine choline deficient diet-induced nonalcoholic steatohepatitis models in miceVSL#3 probiotic treatment attenuates fibrosis without changes in steatohepatitis in a diet-induced nonalcoholic steatohepatitis model in mice.Hepatic retinol secretion and storage are altered by dietary CLA: common and distinct actions of CLA c9,t11 and t10,c12 isomers.Apoptosis and cytokines in non-alcoholic steatohepatitis.Genetic dissection of retinoid esterification and accumulation in the liver and adipose tissue.Pathophysiology of NASH: perspectives for a targeted treatment.New insights from rodent models of fatty liver diseaseCytochrome P450 2E1 and hyperglycemia-induced liver injury.Retinoids and their target genes in liver functions and diseases.New perspectives on the development of antiobesity drugs.The stellate cell system (vitamin A-storing cell system).Connexin 32 and luteolin play protective roles in non-alcoholic steatohepatitis development and its related hepatocarcinogenesis in rats.Is hepatic lipogenesis fundamental for NAFLD/NASH? A focus on the nuclear receptor coactivator PGC-1β.Hepatic Retinyl Ester Hydrolases and the Mobilization of Retinyl Ester Stores.An integrated view of liver injury and disease progression in nonalcoholic steatohepatitis.Hepatocyte caspase-8 is an essential modulator of steatohepatitis in rodents.MicroRNA-30a ameliorates hepatic fibrosis by inhibiting Beclin1-mediated autophagy.Increased SSeCKS expression in rat hepatic stellate cells upon activation in vitro and in vivo.Targeting Hepatic Glycerolipid Synthesis and Turnover to Treat Fatty Liver Disease
P2860
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P2860
Diacylglycerol acyltranferase 1 anti-sense oligonucleotides reduce hepatic fibrosis in mice with nonalcoholic steatohepatitis
description
2008 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Februar 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/02/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/02/01)
@nl
наукова стаття, опублікована в лютому 2008
@uk
مقالة علمية (نشرت في فبراير 2008)
@ar
name
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@ast
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@en
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@nl
type
label
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@ast
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@en
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@nl
prefLabel
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@ast
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@en
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@nl
P2093
P356
P1433
P1476
Diacylglycerol acyltranferase ...... h nonalcoholic steatohepatitis
@en
P2093
Anna Mae Diehl
Brett P. Monia
Jiawen Huang
Kanji Yamaguchi
Sanjay Bhanot
Sanjay K. Pandey
Shannon McCall
Xing Xian Yu
Yin-Xiong Li
P304
P356
10.1002/HEP.21988
P407
P577
2008-02-01T00:00:00Z