Interactions of GIPC with dopamine D2, D3 but not D4 receptors define a novel mode of regulation of G protein-coupled receptors
about
G protein-coupled receptors participate in cytokinesisPhysical and functional interactions of the lysophosphatidic acid receptors with PDZ domain-containing Rho guanine nucleotide exchange factors (RhoGEFs)Role of PDZ proteins in regulating trafficking, signaling, and function of GPCRs: means, motif, and opportunityGLUT1CBP(TIP2/GIPC1) interactions with GLUT1 and myosin VI: evidence supporting an adapter function for GLUT1CBPBinding of internalized receptors to the PDZ domain of GIPC/synectin recruits myosin VI to endocytic vesiclesGAIP interacting protein C-terminus regulates autophagy and exosome biogenesis of pancreatic cancer through metabolic pathwaysSchizophrenia, amphetamine-induced sensitized state and acute amphetamine exposure all show a common alteration: increased dopamine D2 receptor dimerizationD2 dopamine receptor expression and trafficking is regulated through direct interactions with ZIPLow affinity binding of the classical D1 antagonist SCH23390 in rodent brain: potential interaction with A2A and D2-like receptorsRegulation of GPCR activity, trafficking and localization by GPCR-interacting proteins.Functional proteomics, human genetics and cancer biology of GIPC family membersSubapical localization of the dopamine D3 receptor in proximal tubules of the rat kidney.Alix (AIP1) is a vasopressin receptor (V2R)-interacting protein that increases lysosomal degradation of the V2R.Human papillomavirus type 18 E6 protein binds the cellular PDZ protein TIP-2/GIPC, which is involved in transforming growth factor beta signaling and triggers its degradation by the proteasomeManipulation of the Host Cell Membrane during Plasmodium Liver Stage EgressUse of flow cytometric methods to quantify protein-protein interactions.Structure analyses reveal a regulated oligomerization mechanism of the PlexinD1/GIPC/myosin VI complexGIPC1 interacts with MyoGEF and promotes MDA-MB-231 breast cancer cell invasion.Regulation of dopamine D3 receptors by protein-protein interactionsMolecular characterization and ligand binding specificity of the PDZ domain-containing protein GIPC3 from Schistosoma japonicum.The PDZ protein GIPC regulates trafficking of the LPA1 receptor from APPL signaling endosomes and attenuates the cell's response to LPA.A mechanistic role of Helix 8 in GPCRs: Computational modeling of the dopamine D2 receptor interaction with the GIPC1-PDZ-domain.GIPC is recruited by APPL to peripheral TrkA endosomes and regulates TrkA trafficking and signalingInteractions between GIPC-APPL and GIPC-TRP1 regulate melanosomal protein trafficking and melanogenesis in human melanocytes.Dopamine D4 receptor, but not the ADHD-associated D4.7 variant, forms functional heteromers with the dopamine D2S receptor in the brain.Dopamine receptor D3 regulates endocytic sorting by a Prazosin-sensitive interaction with the coatomer COPI.Hypothesis-based RNAi screening identifies neuroprotective genes in a Parkinson's disease model.Dopaminergic intracellular signal integrating proteins: relevance to schizophrenia.A GIPC1-Palmitate Switch Modulates Dopamine Drd3 Receptor Trafficking and Signaling.Targeting GIPC/synectin in pancreatic cancer inhibits tumor growth.GIPC recruits GAIP (RGS19) to attenuate dopamine D2 receptor signaling.Regulation of VEGF signaling by membrane traffic.A perspective on more effective GPCR-targeted drug discovery efforts.A synergistic approach towards understanding the functional significance of dopamine receptor interactions.Minireview: Role of intracellular scaffolding proteins in the regulation of endocrine G protein-coupled receptor signaling.A proteomic analysis of LRRK2 binding partners reveals interactions with multiple signaling components of the WNT/PCP pathway.Dopamine Receptor Signaling in MIN6 β-Cells Revealed by Fluorescence Fluctuation SpectroscopyAPPL1 associates with TrkA and GIPC1 and is required for nerve growth factor-mediated signal transduction.TRP1 interacting PDZ-domain protein GIPC forms oligomers and is localized to intracellular vesicles in human melanocytes.Synectin-dependent regulation of arterial maturation.
P2860
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P2860
Interactions of GIPC with dopamine D2, D3 but not D4 receptors define a novel mode of regulation of G protein-coupled receptors
description
2004 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Februar 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/02/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/02/01)
@nl
наукова стаття, опублікована в лютому 2004
@uk
مقالة علمية (نشرت في فبراير 2004)
@ar
name
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@ast
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@en
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@nl
type
label
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@ast
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@en
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@nl
prefLabel
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@ast
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@en
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@nl
P2093
P2860
P356
P1476
Interactions of GIPC with dopa ...... of G protein-coupled receptors
@en
P2093
Freddy Jeanneteau
Jorge Diaz
Nathalie Griffon
Pierre Sokoloff
P2860
P304
P356
10.1091/MBC.E03-05-0293
P577
2004-02-01T00:00:00Z