Decameric GTP cyclohydrolase I forms complexes with two pentameric GTP cyclohydrolase I feedback regulatory proteins in the presence of phenylalanine or of a combination of tetrahydrobiopterin and GTP
about
A yeast 2-hybrid analysis of human GTP cyclohydrolase I protein interactionsTetrahydrobiopterin biosynthesis, regeneration and functionsZinc plays a key role in human and bacterial GTP cyclohydrolase ICrystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP.Ligand binding to the inhibitory and stimulatory GTP cyclohydrolase I/GTP cyclohydrolase I feedback regulatory protein complexesPet-1 Controls Tetrahydrobiopterin Pathway and Slc22a3 Transporter Genes in Serotonin NeuronsStructural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory proteinThe protein partners of GTP cyclohydrolase I in rat organsThe mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory proteinCoherent conformational degrees of freedom as a structural basis for allosteric communication.A novel high-throughput screening assay for discovery of molecules that increase cellular tetrahydrobiopterin.Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein.Folate synthesis in plants: the first step of the pterin branch is mediated by a unique bimodular GTP cyclohydrolase IThe N-terminal peptide of mammalian GTP cyclohydrolase I is an autoinhibitory control element and contributes to binding the allosteric regulatory protein GFRP.Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approachesFolates in Plants: Research Advances and Progress in Crop BiofortificationGuanosine triphosphate cyclohydrolase I expression and enzymatic activity are present in caveolae of endothelial cells.Identification of proteins interacting with GTP cyclohydrolase I.Folate biofortification in tomatoes by engineering the pteridine branch of folate synthesis.Characterization of transgenic Gfrp knock-in mice: implications for tetrahydrobiopterin in modulation of normal tissue radiation responsesGTP cyclohydrolase I phosphorylation and interaction with GTP cyclohydrolase feedback regulatory protein provide novel regulation of endothelial tetrahydrobiopterin and nitric oxide.GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.GTP cyclohydrolase I: purification, characterization, and effects of inhibition on nitric oxide synthase in nocardia species.Reconstitution of a metabolic pathway with triple-cistronic IRES-containing retroviral vectors for correction of tetrahydrobiopterin deficiency.Role of increased guanosine triphosphate cyclohydrolase-1 expression and tetrahydrobiopterin levels upon T cell activation.Tetrahydrobiopterin deficiency and nitric oxide synthase uncoupling contribute to atherosclerosis induced by disturbed flow.Rice folate enhancement through metabolic engineering has an impact on rice seed metabolism, but does not affect the expression of the endogenous folate biosynthesis genes.Functional interactions between GTP cyclohydrolase I and tyrosine hydroxylase in Drosophila.Structures and reaction mechanisms of GTP cyclohydrolases.
P2860
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P2860
Decameric GTP cyclohydrolase I forms complexes with two pentameric GTP cyclohydrolase I feedback regulatory proteins in the presence of phenylalanine or of a combination of tetrahydrobiopterin and GTP
description
1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
1998 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1998
@ast
im August 1998 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1998/08/07)
@sk
vědecký článek publikovaný v roce 1998
@cs
wetenschappelijk artikel (gepubliceerd op 1998/08/07)
@nl
наукова стаття, опублікована в серпні 1998
@uk
name
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@ast
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@en
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@nl
type
label
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@ast
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@en
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@nl
prefLabel
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@ast
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@en
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@nl
P2860
P356
P1476
Decameric GTP cyclohydrolase I ...... of tetrahydrobiopterin and GTP
@en
P2093
K. Hatakeyama
T. Yoneyama
P2860
P304
20102–20108
P356
10.1074/JBC.273.32.20102
P407
P577
1998-08-07T00:00:00Z