Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
about
Gene, Stem Cell, and Alternative Therapies for SCA 1Experimental neurotransplantation treatment for hereditary cerebellar ataxiasPrecision medicine in spinocerebellar ataxias: treatment based on common mechanisms of diseaseCell biology of spinocerebellar ataxiaMouse models of polyglutamine diseases: review and data table. Part IIntegration of modeling with experimental and clinical findings synthesizes and refines the central role of inositol 1,4,5-trisphosphate receptor 1 in spinocerebellar ataxiaMouse models of polyglutamine diseases in therapeutic approaches: review and data table. Part II.Inactivation of ca10a and ca10b Genes Leads to Abnormal Embryonic Development and Alters Movement Pattern in ZebrafishCA8 mutations cause a novel syndrome characterized by ataxia and mild mental retardation with predisposition to quadrupedal gaitSilencing mutant ataxin-3 rescues motor deficits and neuropathology in Machado-Joseph disease transgenic miceMotor Dysfunctions and Neuropathology in Mouse Models of Spinocerebellar Ataxia Type 2: A Comprehensive ReviewCalcium dysregulation links ALS defective proteins and motor neuron selective vulnerabilityTherapeutic prospects for spinocerebellar ataxia type 2 and 3.Serotonergic signalling suppresses ataxin 3 aggregation and neurotoxicity in animal models of Machado-Joseph disease.Long-term dantrolene treatment reduced intraneuronal amyloid in aged Alzheimer triple transgenic miceNucleocytoplasmic shuttling activity of ataxin-3.Ataxin-3 promotes genome integrity by stabilizing Chk1.The enigma of store-operated ca-entry in neurons: answers from the Drosophila flight circuit.Inositol trisphosphate receptor Ca2+ release channels in neurological diseases.Role of presenilins in neuronal calcium homeostasisMilestones in ataxiaComputational analysis of calcium signaling and membrane electrophysiology in cerebellar Purkinje neurons associated with ataxia.Role of inositol 1,4,5-trisphosphate receptors in pathogenesis of Huntington's disease and spinocerebellar ataxiasComputational neurobiology is a useful tool in translational neurology: the example of ataxiaBilayer measurement of endoplasmic reticulum Ca2+ channels.SCA15 due to large ITPR1 deletions in a cohort of 333 white families with dominant ataxia.Early changes in cerebellar physiology accompany motor dysfunction in the polyglutamine disease spinocerebellar ataxia type 3Calcium dysregulation via L-type voltage-dependent calcium channels and ryanodine receptors underlies memory deficits and synaptic dysfunction during chronic neuroinflammationAbnormalities in the climbing fiber-Purkinje cell circuitry contribute to neuronal dysfunction in ATXN1[82Q] miceExpanded polyglutamine-binding peptoid as a novel therapeutic agent for treatment of Huntington's disease.The role for alterations in neuronal activity in the pathogenesis of polyglutamine repeat disorders.Protein interacting with C kinase (PICK1) is a suppressor of spinocerebellar ataxia 3-associated neurodegeneration in Drosophila.Dantrolene is neuroprotective in Huntington's disease transgenic mouse model.Deranged calcium signaling in Purkinje cells and pathogenesis in spinocerebellar ataxia 2 (SCA2) and other ataxiasToward understanding Machado-Joseph diseaseRyanodine receptor blockade reduces amyloid-β load and memory impairments in Tg2576 mouse model of Alzheimer disease.Chronic suppression of inositol 1,4,5-triphosphate receptor-mediated calcium signaling in cerebellar purkinje cells alleviates pathological phenotype in spinocerebellar ataxia 2 miceHuman ataxias: a genetic dissection of inositol triphosphate receptor (ITPR1)-dependent signaling.Enhanced Store-Operated Calcium Entry Leads to Striatal Synaptic Loss in a Huntington's Disease Mouse Model.Stress, caffeine and ethanol trigger transient neurological dysfunction through shared mechanisms in a mouse calcium channelopathy
P2860
Q26738497-BA52027D-499A-49C6-8B18-6F59289D511DQ26752137-6612D770-8A32-4754-96A5-3BA0AD0A81FBQ26764958-3AB55718-30E3-4E17-93C8-AB4E1897613EQ26829511-C62A35A8-006D-465E-A8FC-A910FB863EEFQ26853025-7EF8D09F-D055-409E-8E0D-DBA9F17A2FA4Q26864714-2D7A348B-DEBE-4BE0-A826-5CF3C2B94090Q27005950-2DD377FC-A4FC-44AC-8BF1-7E187BE88429Q27301392-FD0C6B62-CB30-46E8-8877-602525341176Q27312310-6AB75BE6-C93E-47FF-9D20-31502EF14AE9Q27324749-E7F9DAC0-0AEB-4DC8-8EC3-DF76352DC84AQ28076174-5FFB1584-C34A-4046-B67C-F6FE140E4C0FQ28084373-32727E22-6129-4A3E-AEBE-045D8AC50F6FQ30410969-CC5DF36D-6A1E-4427-9068-A78A9253797FQ30703360-0B595E43-CA74-448B-8C11-CCEBE6CFFA1FQ30887483-5A4F35ED-90CD-4921-ADA2-0CEDAC20285DQ33463406-BE5A54C3-3E5E-4403-AAAA-46AA3C4AD228Q33635896-7A8F94D0-5DCF-4F06-95F8-0908F46B1406Q33797885-B1057313-2FC1-44B3-93CD-6BA6FF80CEEDQ33946097-99F4F4EC-3D20-4A28-A34A-573DAAF1B3CEQ34003214-D5633DE1-8312-41D6-ADFB-95B5B5CD8013Q34188468-51DDBDC5-2879-426A-865C-355B19A81D1AQ34306449-3547D15E-27EA-43FB-A0D4-75AD6D648137Q34981549-DF24E185-216E-4DD6-992E-003784CEC274Q34992022-F1100F83-B29A-4CCA-BFE7-26855D5DD8B9Q35049794-716D4BFA-1FA7-473F-AE62-D2C3E60BFA58Q35125192-2670FBBB-0732-48DE-9FA3-3FA00AFCC40FQ35205602-0DBFFAAA-E41B-4496-BD3C-3A03C43D6EDCQ35226213-B938D100-DB90-4B14-A2C2-647A573E0223Q35227534-12B9EBF8-1ED0-4587-884E-08601E3EDCC1Q35244160-DBD666A7-640B-4783-8DC8-77F6644D0F64Q35340099-1569A594-629C-40EB-BB79-47453116600DQ35605199-339DC4F1-7F81-4A32-9191-DBE85AEF0BE1Q35605391-284D1DB0-F909-49FF-94EA-86B09DAE8E1EQ35670193-1E12A344-6046-4BB1-83EF-F297916AB1BEQ35837355-E40C380A-6E92-4FFC-ADF6-4276EE57A254Q36279483-50C4EBEB-6697-4EFD-B26E-3D0551154DA4Q36315976-CDCCBCE1-7F24-431A-8D2D-C77AD7800848Q36384774-A6F49E91-46C6-44C4-A9E4-6781F7CD5E49Q36431970-B0F021C8-4A41-4766-A1F4-811DF783FB0AQ36501625-A0119827-56F5-45F4-9605-850C63FCFFF9
P2860
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
description
2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im November 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/11/26)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/11/26)
@nl
наукова стаття, опублікована в листопаді 2008
@uk
مقالة علمية (نشرت في 26-11-2008)
@ar
name
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@ast
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@en
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@nl
type
label
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@ast
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@en
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@nl
prefLabel
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@ast
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@en
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@nl
P2093
P2860
P3181
P1476
Deranged calcium signaling and neurodegeneration in spinocerebellar ataxia type 3
@en
P2093
Huiping Tu
Ilya Bezprozvanny
Nobuyuki Nukina
Omar Nelson
Robert Hammer
Tie-Shan Tang
P2860
P304
12713–12724
P3181
P356
10.1523/JNEUROSCI.3909-08.2008
P407
P577
2008-11-26T00:00:00Z