Oligomerization of serotonin transporter and its functional consequences
about
Plasma serotonin levels and the platelet serotonin transporterSerotonin transamidates Rab4 and facilitates its binding to the C terminus of serotonin transporterPit2 assemblies at the cell surface are modulated by extracellular inorganic phosphate concentrationOverexpression of membrane proteins in mammalian cells for structural studiesFunctional expression, purification and reconstitution of the recombinant phosphate transporter Pho89 of Saccharomyces cerevisiae.Immunomodulatory effects mediated by serotoninA trimeric quaternary structure is conserved in bacterial and human glutamate transportersRole of the dopamine transporter in the action of psychostimulants, nicotine, and other drugs of abuseRecognition of psychostimulants, antidepressants, and other inhibitors of synaptic neurotransmitter uptake by the plasma membrane monoamine transportersRole of the conserved glutamine 291 in the rat gamma-aminobutyric acid transporter rGAT-1Glycosyl modification facilitates homo- and hetero-oligomerization of the serotonin transporter. A specific role for sialic acid residuesA novel topology and redox regulation of the rat brain K+-dependent Na+/Ca2+ exchanger, NCKX2The large extracellular loop of organic cation transporter 1 influences substrate affinity and is pivotal for oligomerizationCurrent carried by the Slc26 family member prestin does not flow through the transporter pathway.Blood-brain barrier genomics and cloning of a novel organic anion transporter.Norepinephrine transporter variant A457P knock-in mice display key features of human postural orthostatic tachycardia syndrome.GABA transporter function, oligomerization state, and anchoring: correlates with subcellularly resolved FRETTransmembrane domain 6 of the human serotonin transporter contributes to an aqueously accessible binding pocket for serotonin and the psychostimulant 3,4-methylene dioxymethamphetamine.Structural analysis of the extracellular entrance to the serotonin transporter permeation pathway.Symmetrical dimer of the human dopamine transporter revealed by cross-linking Cys-306 at the extracellular end of the sixth transmembrane segment.Interrelation of dopamine transporter oligomerization and surface presence as studied with mutant transporter proteins and amphetamine.Unbiased simulations reveal the inward-facing conformation of the human serotonin transporter and Na(+) ion release.Surface-localized glycine transporters 1 and 2 function as monomeric proteins in Xenopus oocytesMonoamine transporter gene structure and polymorphisms in relation to psychiatric and other complex disorders.Molecular mechanisms of SERT in platelets: regulation of plasma serotonin levels.X-ray structures and mechanism of the human serotonin transporter.Regulation of monoamine transporters: Role of transporter phosphorylation.Functional consequences of homo- but not hetero-oligomerization between transporters for the biogenic amine neurotransmitters.At diabetes-like concentration, glucose down-regulates the placental serotonin transport system in a cell-cycle-dependent mannerGDM-associated insulin deficiency hinders the dissociation of SERT from ERp44 and down-regulates placental 5-HT uptakeMonoamine reuptake inhibitors in Parkinson's disease.Properties of an inward-facing state of LeuT: conformational stability and substrate release.Dopamine transporter oligomerization: impact of combining protomers with differential cocaine analog binding affinitiesUnifying concept of serotonin transporter-associated currentsPrevalence of Intervillous Thrombi Is Increased in Placentas from Pregnancies Complicated by Diabetes.The role of ERp44 in maturation of serotonin transporter protein.A Single Pair of Serotonergic Neurons Counteracts Serotonergic Inhibition of Ethanol Attraction in Drosophila.Three-dimensional models of neurotransmitter transporters and their interactions with cocaine and S-citalopram.5-hydroxytryptamine in the cardiovascular system: focus on the serotonin transporter (SERT).The synthesis of bivalent 2beta-carbomethoxy-3beta-(3,4-dichlorophenyl)-8-heterobicyclo[3.2.1]octanes as probes for proximal binding sites on the dopamine and serotonin transporters.
P2860
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P2860
Oligomerization of serotonin transporter and its functional consequences
description
2000 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2000
@ast
im März 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/03/28)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/03/28)
@nl
наукова стаття, опублікована в березні 2000
@uk
name
Oligomerization of serotonin transporter and its functional consequences
@ast
Oligomerization of serotonin transporter and its functional consequences
@en
Oligomerization of serotonin transporter and its functional consequences
@nl
type
label
Oligomerization of serotonin transporter and its functional consequences
@ast
Oligomerization of serotonin transporter and its functional consequences
@en
Oligomerization of serotonin transporter and its functional consequences
@nl
prefLabel
Oligomerization of serotonin transporter and its functional consequences
@ast
Oligomerization of serotonin transporter and its functional consequences
@en
Oligomerization of serotonin transporter and its functional consequences
@nl
P2860
P1476
Oligomerization of serotonin transporter and its functional consequences
@en
P2093
P2860
P304
P356
10.1073/PNAS.060408997
10.1073/PNAS.97.7.3106
P407
P577
2000-03-28T00:00:00Z