X-ray structures and mechanism of the human serotonin transporter.
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A current view of serotonin transportersThe Use of Multiscale Molecular Simulations in Understanding a Relationship between the Structure and Function of Biological Systems of the Brain: The Application to Monoamine Oxidase EnzymesNeurobiology of Anorexia Nervosa: Serotonin Dysfunctions Link Self-Starvation with Body Image Disturbances through an Impaired Body MemoryTransporter oligomerization: form and functionMapping Cholesterol Interaction Sites on Serotonin Transporter through Coarse-Grained Molecular DynamicsFrom linked open data to molecular interaction: studying selectivity trends for ligands of the human serotonin and dopamine transporterDirect assessment of substrate binding to the Neurotransmitter:Sodium Symporter LeuT by solid state NMRTargeting Neuroblastoma Cell Surface Proteins: Recommendations for Homology Modeling of hNET, ALK, and TrkBStructural and mechanistic basis of proton-coupled metal ion transport in the SLC11/NRAMP family.Identification of novel inhibitors of the amino acid transporter B0 AT1 (SLC6A19), a potential target to induce protein restriction and to treat type 2 diabetes.Targeting of dopamine transporter to filopodia requires an outward-facing conformation of the transporter.Transition metal ion FRET uncovers K(+) regulation of a neurotransmitter/sodium symporter.Genome-Wide Identification, Characterization and Expression Analysis of the Solute Carrier 6 Gene Family in Silkworm (Bombyx mori).A Markov State-based Quantitative Kinetic Model of Sodium Release from the Dopamine Transporter.Thermostabilization, Expression, Purification, and Crystallization of the Human Serotonin Transporter Bound to S-citalopram.Direct PIP2 binding mediates stable oligomer formation of the serotonin transporterInfluence of fluvoxamine on plasma interleukin-6 or clinical improvement in patients with major depressive disorder.Sequence determinants of the Caenhorhabditis elegans dopamine transporter dictating in vivo axonal export and synaptic localization.Dopamine Transporter Amino and Carboxyl Termini Synergistically Contribute to Substrate and Inhibitor Affinities.Impact of disruption of secondary binding site S2 on dopamine transporter function.Modulation of LAT1 (SLC7A5) transporter activity and stability by membrane cholesterol.The development of novel polypharmacological agents targeting the multiple binding sites of nicotinic acetylcholine receptors.An Extra Amino Acid Residue in Transmembrane Domain 10 of the γ-Aminobutyric Acid (GABA) Transporter GAT-1 Is Required for Efficient Ion-coupled Transport.The proton-coupled folate transporter (PCFT-SLC46A1) and the syndrome of systemic and cerebral folate deficiency of infancy: Hereditary folate malabsorption.Application of a Combined Approach to Identify New Psychoactive Street Drugs and Decipher Their Mechanisms at Monoamine Transporters.Alternating access mechanisms of LeuT-fold transporters: trailblazing towards the promised energy landscapes.Electrogenic Binding of Intracellular Cations Defines a Kinetic Decision Point in the Transport Cycle of the Human Serotonin Transporter.A Dynamic Interaction of Coomassie Dye with the Glycine Transporters N-termini.Chansporter complexes in cell signaling.The role of interfacial lipids in stabilizing membrane protein oligomers.Cryo-EM structures of the triheteromeric NMDA receptor and its allosteric modulation.The N Terminus Specifies the Switch between Transport Modes of the Human Serotonin Transporter.Structural basis of pH-dependent client binding by ERp44, a key regulator of protein secretion at the ER-Golgi interface.Revised Ion/Substrate Coupling Stoichiometry of GABA Transporters.An unfolding story: Small molecules remedy misfolded monoamine transporters.Overview of Monoamine Transporters.Latch and trigger role for R445 in DAT transport explains molecular basis of DTDS.Current and Future Challenges in GPCR Drug Discovery.Allosteric modulation of human dopamine transporter activity under conditions promoting its dimerization.SLC6 Transporter Folding Diseases and Pharmacochaperoning.
P2860
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P2860
X-ray structures and mechanism of the human serotonin transporter.
description
2016 nî lūn-bûn
@nan
2016 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2016 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2016年の論文
@ja
2016年論文
@yue
2016年論文
@zh-hant
2016年論文
@zh-hk
2016年論文
@zh-mo
2016年論文
@zh-tw
2016年论文
@wuu
name
X-ray structures and mechanism of the human serotonin transporter.
@ast
X-ray structures and mechanism of the human serotonin transporter.
@en
X-ray structures and mechanism of the human serotonin transporter.
@nl
type
label
X-ray structures and mechanism of the human serotonin transporter.
@ast
X-ray structures and mechanism of the human serotonin transporter.
@en
X-ray structures and mechanism of the human serotonin transporter.
@nl
prefLabel
X-ray structures and mechanism of the human serotonin transporter.
@ast
X-ray structures and mechanism of the human serotonin transporter.
@en
X-ray structures and mechanism of the human serotonin transporter.
@nl
P2093
P2860
P356
P1433
P1476
X-ray structures and mechanism of the human serotonin transporter.
@en
P2093
Eric Gouaux
Evan M Green
Jonathan A Coleman
P2860
P2888
P304
P356
10.1038/NATURE17629
P407
P577
2016-04-06T00:00:00Z
P6179
1030704609