Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens
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End-plate acetylcholine receptor: structure, mechanism, pharmacology, and diseaseDefects of the Glycinergic Synapse in Zebrafish.Inhibition of the Prokaryotic Pentameric Ligand-Gated Ion Channel ELIC by Divalent CationsA locally closed conformation of a bacterial pentameric proton-gated ion channelA Conformational Intermediate in Glutamate Receptor ActivationMurine startle mutant Nmf11 affects the structural stability of the glycine receptor and increases deactivation.High intracellular chloride slows the decay of glycinergic currents.Automated maximum likelihood separation of signal from baseline in noisy quantal data.Analysis of single ion channel data incorporating time-interval omission and sampling.Achieving maximal speed of solution exchange for patch clamp experiments.The ion channel inverse problem: neuroinformatics meets biophysics.Identification of a pre-active conformation of a pentameric channel receptorThe activation mechanism of alpha1beta2gamma2S and alpha3beta3gamma2S GABAA receptors.Conformational changes in the nicotinic acetylcholine receptor during gating and desensitizationThe relationship between agonist potency and AMPA receptor kinetics.β Subunit M2-M3 loop conformational changes are uncoupled from α1 β glycine receptor channel gating: implications for human hereditary hyperekplexia.Efficient maximum likelihood estimation of kinetic rate constants from macroscopic currentsSensory gating of an embryonic zebrafish interneuron during spontaneous motor behaviors.Probability fluxes and transition paths in a Markovian model describing complex subunit cooperativity in HCN2 channelsStatistical evaluation of ion-channel gating models based on distributions of log-likelihood ratios.On the nature of partial agonism in the nicotinic receptor superfamily.Detection and trapping of intermediate states priming nicotinic receptor channel opening.Correlating structural and energetic changes in glycine receptor activation.Zolpidem and eszopiclone prime α1β2γ2 GABAA receptors for longer duration of activity.Novel beta subunit mutation causes a slow-channel syndrome by enhancing activation and decreasing the rate of agonist dissociationEstimating binding affinities of the nicotinic receptor for low-efficacy ligands using mixtures of agonists and two-dimensional concentration-response relationshipsResponses of rat P2X2 receptors to ultrashort pulses of ATP provide insights into ATP binding and channel gatingStoichiometry of the human glycine receptor revealed by direct subunit counting.Conformational Flip of Nonactivated HCN2 Channel Subunits Evoked by Cyclic Nucleotides.Agonist-activated ion channels.Differential distribution of glycine receptor subtypes at the rat calyx of Held synapse.Improved resolution of single channel dwell times reveals mechanisms of binding, priming, and gating in muscle AChR.Intermediate closed state for glycine receptor function revealed by cysteine cross-linking.Propofol modulation of α1 glycine receptors does not require a structural transition at adjacent subunits that is crucial to agonist-induced activationSingle-channel kinetic analysis for activation and desensitization of homomeric 5-HT(3)A receptors.The unique α4+/-α4 agonist binding site in (α4)3(β2)2 subtype nicotinic acetylcholine receptors permits differential agonist desensitization pharmacology versus the (α4)2(β2)3 subtypeDetermining the neurotransmitter concentration profile at active synapses.Glycine Receptors Caught between Genome and Proteome - Functional Implications of RNA Editing and Splicing.Magnitude of a conformational change in the glycine receptor beta1-beta2 loop is correlated with agonist efficacy.What single-channel analysis tells us of the activation mechanism of ligand-gated channels: the case of the glycine receptor.
P2860
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P2860
Single-channel behavior of heteromeric alpha1beta glycine receptors: an attempt to detect a conformational change before the channel opens
description
2004 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Dezember 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/12/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/12/01)
@nl
наукова стаття, опублікована в грудні 2004
@uk
مقالة علمية (نشرت في ديسمبر 2004)
@ar
name
Single-channel behavior of het ...... hange before the channel opens
@ast
Single-channel behavior of het ...... hange before the channel opens
@en
Single-channel behavior of het ...... hange before the channel opens
@nl
type
label
Single-channel behavior of het ...... hange before the channel opens
@ast
Single-channel behavior of het ...... hange before the channel opens
@en
Single-channel behavior of het ...... hange before the channel opens
@nl
altLabel
Single-Channel Behavior of Het ...... hange before the Channel Opens
@en
prefLabel
Single-channel behavior of het ...... hange before the channel opens
@ast
Single-channel behavior of het ...... hange before the channel opens
@en
Single-channel behavior of het ...... hange before the channel opens
@nl
P2093
P3181
P1476
Single-channel behavior of het ...... hange before the channel opens
@en
P2093
David Colquhoun
Paul J Groot-Kormelink
Valeria Burzomato
P304
10924-10940
P3181
P356
10.1523/JNEUROSCI.3424-04.2004
P407
P577
2004-12-01T00:00:00Z