Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model
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The human proton-coupled folate transporter (hPCFT): modulation of intestinal expression and function by drugsBiology of the major facilitative folate transporters SLC19A1 and SLC46A1The molecular basis of folate salvage in Plasmodium falciparum: characterization of two folate transportersSubstituted cysteine accessibility reveals a novel transmembrane 2-3 reentrant loop and functional role for transmembrane domain 2 in the human proton-coupled folate transporter.Intestinal absorption of water-soluble vitamins in health and diseaseMechanisms of membrane transport of folates into cells and across epithelia.The human proton-coupled folate transporter: Biology and therapeutic applications to cancer.The intestinal absorption of folates.Iron metabolism in thalassemia and sickle cell diseaseMembrane transporters and folate homeostasis: intestinal absorption and transport into systemic compartments and tissues.Activation and inhibition of the micturition reflex by penile afferents in the cat.Intestinal transport of aminopterin enantiomers in dogs and humans with psoriasis is stereoselective: evidence for a mechanism involving the proton-coupled folate transporter.Absorption and blood/cellular transport of folate and cobalamin: Pharmacokinetic and physiological considerationsInhibition of the proton-coupled folate transporter (PCFT-SLC46A1) by bicarbonate and other anions.Differential effects of urethane and isoflurane on external urethral sphincter electromyography and cystometry in ratsFunctional characterization of folate transport proteins in Staten's Seruminstitut rabbit corneal epithelial cell lineA role for the proton-coupled folate transporter (PCFT-SLC46A1) in folate receptor-mediated endocytosis.Involvement of Multiple Transporters-mediated Transports in Mizoribine and Methotrexate Pharmacokinetics.Mechanism and regulation of folate uptake by pancreatic acinar cells: effect of chronic alcohol consumption.Tumor Targeting with Novel 6-Substituted Pyrrolo [2,3-d] Pyrimidine Antifolates with Heteroatom Bridge Substitutions via Cellular Uptake by Folate Receptor α and the Proton-Coupled Folate Transporter and Inhibition of de Novo Purine Nucleotide BiosyFunctional and mechanistic roles of the human proton-coupled folate transporter transmembrane domain 6-7 linker.The major facilitative folate transporters solute carrier 19A1 and solute carrier 46A1: biology and role in antifolate chemotherapy of cancer.Hijacking solute carriers for proton-coupled drug transport.Post-hatching ontogeny of intestinal proton-coupled folate transporter and reduced folate carrier in broiler chickens.Antiepileptic drugs reduce the efficacy of methotrexate chemotherapy through accelerated degradation of the reduced folate carrier by the ubiquitin-proteasome pathway.Identification and functional characterization of the first nucleobase transporter in mammals: implication in the species difference in the intestinal absorption mechanism of nucleobases and their analogs between higher primates and other mammalsHaemopexin affects iron distribution and ferritin expression in mouse brain.Proton-coupled folate transporter (PCFT): molecular cloning, tissue expression patterns and the effects of dietary folate supplementation on mRNA expression in laying hens.Mechanisms of heme iron absorption: current questions and controversies.Haem and folate transport by proton-coupled folate transporter/haem carrier protein 1 (SLC46A1).Site-specific contribution of proton-coupled folate transporter/haem carrier protein 1 in the intestinal absorption of methotrexate in rats.Absorption sites of orally administered drugs in the small intestine.The promise and challenges of exploiting the proton-coupled folate transporter for selective therapeutic targeting of cancer.Development and validation of chemical features-based proton-coupled folate transporter/activity and reduced folate carrier/activity models (pharmacophores).Folate malabsorption is associated with down-regulation of folate transporter expression and function at colon basolateral membrane in rats.Urate transport function of rat sodium-dependent nucleobase transporter 1.
P2860
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P2860
Functional characterization of PCFT/HCP1 as the molecular entity of the carrier-mediated intestinal folate transport system in the rat model
description
2008 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
scientific journal article
@en
vedecký článok (publikovaný 2008/03/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/03/01)
@nl
наукова стаття, опублікована в березні 2008
@uk
مقالة علمية (نشرت في مارس 2008)
@ar
name
Functional characterization of ...... nsport system in the rat model
@ast
Functional characterization of ...... nsport system in the rat model
@en
Functional characterization of ...... nsport system in the rat model
@nl
type
label
Functional characterization of ...... nsport system in the rat model
@ast
Functional characterization of ...... nsport system in the rat model
@en
Functional characterization of ...... nsport system in the rat model
@nl
prefLabel
Functional characterization of ...... nsport system in the rat model
@ast
Functional characterization of ...... nsport system in the rat model
@en
Functional characterization of ...... nsport system in the rat model
@nl
P2093
P2860
P356
P1476
Functional characterization of ...... nsport system in the rat model
@en
P2093
Katsuhisa Inoue
Kin-ya Ohta
Mai Hatakeyama
Masaki Otagiri
Sayaka Ueda
Shunsuke Kamigaso
Yasuhiro Nakai
Yayoi Hayashi
P2860
P304
P356
10.1152/AJPGI.00309.2007
P577
2008-01-03T00:00:00Z