Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
about
Intestinal apolipoprotein AI gene transcription is regulated by multiple distinct DNA elements and is synergistically activated by the orphan nuclear receptor, hepatocyte nuclear factor 4Retinoid X receptor-COUP-TF interactions modulate retinoic acid signalingAntagonism between apolipoprotein AI regulatory protein 1, Ear3/COUP-TF, and hepatocyte nuclear factor 4 modulates apolipoprotein CIII gene expression in liver and intestinal cellsMarked reduction of high density lipoprotein cholesterol in mice genetically modified to lack apolipoprotein A-IThe SP1 sites of the human apoCIII enhancer are essential for the expression of the apoCIII gene and contribute to the hepatic and intestinal expression of the apoA-I gene in transgenic miceAltered regulation of apolipoprotein A-IV gene expression in the liver of the genetically obese Zucker rat.Fibrates downregulate apolipoprotein C-III expression independent of induction of peroxisomal acyl coenzyme A oxidase. A potential mechanism for the hypolipidemic action of fibratesDNA inversion within the apolipoproteins AI/CIII/AIV-encoding gene cluster of certain patients with premature atherosclerosisCOUP-TFs and eye developmentAnti-inflammatory mechanisms of apolipoprotein A-I mimetic peptide in acute respiratory distress syndrome secondary to sepsis.Bile acid-activated nuclear receptor FXR suppresses apolipoprotein A-I transcription via a negative FXR response element.Apolipoprotein C-III: a potent modulator of hypertriglyceridemia and cardiovascular disease.Synergistic interactions between transcription factors control expression of the apolipoprotein AI gene in liver cells.Chicken ovalbumin upstream promoter transcription factor (COUP-TF) dimers bind to different GGTCA response elements, allowing COUP-TF to repress hormonal induction of the vitamin D3, thyroid hormone, and retinoic acid receptors.Different cis-acting DNA elements control expression of the human apolipoprotein AI gene in different cell types.The apolipoprotein CIII enhancer regulates both extensive histone modification and intergenic transcription of human apolipoprotein AI/CIII/AIV genes but not apolipoprotein AV.The full induction of human apoprotein A-I gene expression by the experimental nephrotic syndrome in transgenic mice depends on cis-acting elements in the proximal 256 base-pair promoter region and the trans-acting factor early growth response factoOverexpression of apolipoprotein C-III decreases secretion of dietary triglyceride into lymphTranscriptional regulation of the apoAI gene by hepatic nuclear factor 4 in yeast.Key differences between apoC-III regulation and expression in intestine and liver.Effect of ApoA4 on SERPINA3 mediated by nuclear receptors NR4A1 and NR1D1 in hepatocytes.Foxo1 mediates insulin action on apoC-III and triglyceride metabolism.HNF-4 increases activity of the rat Apo A1 gene.The transcription factor LF-A1 interacts with a bipartite recognition sequence in the promoter regions of several liver-specific genes.Identification of an enhancer-like element in the 5' flanking region of the rat apolipoprotein A-I gene.Intermediate and low abundant protein analysis of vitamin D deficient obese and non-obese subjects by MALDI-profiling.
P2860
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P2860
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
description
1986 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 1986
@ast
im Oktober 1986 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1986/10/05)
@sk
vědecký článek publikovaný v roce 1986
@cs
wetenschappelijk artikel (gepubliceerd op 1986/10/05)
@nl
наукова стаття, опублікована в жовтні 1986
@uk
name
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@ast
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@en
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@nl
type
label
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@ast
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@en
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@nl
prefLabel
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@ast
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@en
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@nl
P2093
P1476
Linkage, evolution, and expression of the rat apolipoprotein A-I, C-III, and A-IV genes
@en
P2093
I. A. Haddad
J. M. Ordovas
S. K. Karathanasis
T. Fitzpatrick
P304
13268–13277
P407
P577
1986-10-05T00:00:00Z