The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
about
An auxiliary factor containing a 240-kDa protein complex is involved in apolipoprotein B RNA editingMetabolic regulation of APOBEC-1 complementation factor trafficking in mouse models of obesity and its positive correlation with the expression of ApoB protein in hepatocytesInterleukin-6 mediates hepatic hypersecretion of apolipoprotein B.Effects of nonketotic streptozotocin diabetes on apolipoprotein B synthesis and secretion by primary cultures of rat hepatocytesAcute suppression of apo B secretion by insulin occurs independently of MTP.Impaired hepatic apolipoprotein B and E translation in streptozotocin diabetic ratsInsulin dependent apolipoprotein B degradation and phosphatidylinositide 3-kinase activation with microsomal translocation are restored in McArdle RH7777 cells following serum deprivation.Insulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting.Sortilin facilitates VLDL-B100 secretion by insulin sensitive McArdle RH7777 cells.Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases.Apolipoprotein B mRNA and lipoprotein secretion are increased in McArdle RH-7777 cells by expression of betaine-homocysteine S-methyltransferase.ABHD5/CGI-58 facilitates the assembly and secretion of apolipoprotein B lipoproteins by McA RH7777 rat hepatoma cells.Extracellular fatty acids are not utilized directly for the synthesis of very-low-density lipoprotein in primary cultures of rat hepatocytes.Inhibition of apolipoprotein B net synthesis and secretion from cultured rat hepatocytes by the calcium-channel blocker diltiazem.Hepatic very-low-density lipoprotein and apolipoprotein B production are increased following in vivo induction of betaine-homocysteine S-methyltransferase.Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes.Phosphoinositide 3-kinase activity is necessary for insulin-dependent inhibition of apolipoprotein B secretion by rat hepatocytes and localizes to the endoplasmic reticulum.Regulation of VLDL secretion in primary culture of rat hepatocytes: involvement of cAMP and cAMP-dependent protein kinases.The role of pancreatic hormones in the regulation of lipid storage, oxidation and secretion in primary cultures of rat hepatocytes. Short- and long-term effects.Rat monoclonal antibodies to rabbit and human serum low-density lipoproteinInsulin effects on apolipoprotein B production by normal, diabetic and treated-diabetic rat liver and cultured rat hepatocytesAltered triglyceride-rich lipoprotein production in Zucker diabetic fatty rats.Glucose-stimulated insulin secretion suppresses hepatic triglyceride-rich lipoprotein and apoB production.
P2860
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P2860
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
description
1986 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
1986 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1986
@ast
im September 1986 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1986/09/01)
@sk
vědecký článek publikovaný v roce 1986
@cs
wetenschappelijk artikel (gepubliceerd op 1986/09/01)
@nl
наукова стаття, опублікована у вересні 1986
@uk
مقالة علمية (نشرت في سبتمبر 1986)
@ar
name
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@ast
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@en
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@nl
type
label
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@ast
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@en
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@nl
prefLabel
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@ast
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@en
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@nl
P2093
P1433
P1476
The production and utility of monoclonal antibodies to rat apolipoprotein B lipoproteins
@en
P2093
C. E. Sparks
J. D. Sparks
M. Bolognino
P. A. Trax
P304
P356
10.1016/0021-9150(86)90139-5
P577
1986-09-01T00:00:00Z