Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes.
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Insulin decreases the secretion of apoB-100 from hepatic HepG2 cells but does not decrease the secretion of apoB-48 from intestinal CaCo-2 cellsThe degradation of apolipoprotein B100: multiple opportunities to regulate VLDL triglyceride production by different proteolytic pathwaysCellular Determinants of Hepatitis C Virus Assembly, Maturation, Degradation, and SecretionEffects of the PPARgamma agonist pioglitazone on lipoprotein metabolism in patients with type 2 diabetes mellitus.A novel role for ABCA1-generated large pre-beta migrating nascent HDL in the regulation of hepatic VLDL triglyceride secretionTargeted deletion of hepatocyte ABCA1 leads to very low density lipoprotein triglyceride overproduction and low density lipoprotein hypercatabolismInsulin-stimulated degradation of apolipoprotein B100: roles of class II phosphatidylinositol-3-kinase and autophagyComplexity in the secretory pathway: the assembly and secretion of apolipoprotein B-containing lipoproteins.Acute suppression of apo B secretion by insulin occurs independently of MTP.Increased very low density lipoprotein (VLDL) secretion, hepatic steatosis, and insulin resistance.Hepatic ABCA1 and VLDL triglyceride production.Identification of two regions in apolipoprotein B100 that are exposed on the cytosolic side of the endoplasmic reticulum membraneInsulin suppression of apolipoprotein B in McArdle RH7777 cells involves increased sortilin 1 interaction and lysosomal targeting.Effect of insulin analog initiation therapy on LDL/HDL subfraction profile and HDL associated enzymes in type 2 diabetic patients.The physiological and molecular regulation of lipoprotein assembly and secretion.Insulin Regulates Hepatic Triglyceride Secretion and Lipid Content via Signaling in the BrainApolipoprotein B secretion is regulated by hepatic triglyceride, and not insulin, in a model of increased hepatic insulin signaling.Hepatic ABC transporters and triglyceride metabolism.Ectopic lipid storage and insulin resistance: a harmful relationship.The regulation of ApoB metabolism by insulin.Insulin-dependent apolipoprotein B degradation is mediated by autophagy and involves class I and class III phosphatidylinositide 3-kinases.Momordica charantia (bitter melon) reduces plasma apolipoprotein B-100 and increases hepatic insulin receptor substrate and phosphoinositide-3 kinase interactions.Development of a 2-D apoB peptide profile to detect conformational changes associated with apoB-containing lipoproteins.Phosphatase and tensin homolog (PTEN) regulates hepatic lipogenesis, microsomal triglyceride transfer protein, and the secretion of apolipoprotein B-containing lipoproteins.Phosphoinositide 3-kinase activity is necessary for insulin-dependent inhibition of apolipoprotein B secretion by rat hepatocytes and localizes to the endoplasmic reticulum.Hepatic very low density lipoprotein-ApoB overproduction is associated with attenuated hepatic insulin signaling and overexpression of protein-tyrosine phosphatase 1B in a fructose-fed hamster model of insulin resistance.The recycling of apolipoprotein E and its amino-terminal 22 kDa fragment: evidence for multiple redundant pathways.Treatment with high-dose simvastatin reduces secretion of apolipoprotein B-lipoproteins in patients with diabetic dyslipidemia.Regulation of hepatic apolipoprotein B-lipoprotein assembly and secretion by the availability of fatty acids. I. Differential response to the delivery of fatty acids via albumin or remnant-like emulsion particles.Glucose-stimulated insulin secretion suppresses hepatic triglyceride-rich lipoprotein and apoB production.The role of factors that regulate the synthesis and secretion of very-low-density lipoprotein by hepatocytes.PI3-kinase activity modulates apo B available for hepatic VLDL production in apobec-1-/- mice.
P2860
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P2860
Insulin-mediated inhibition of apolipoprotein B secretion requires an intracellular trafficking event and phosphatidylinositol 3-kinase activation: studies with brefeldin A and wortmannin in primary cultures of rat hepatocytes.
description
1996 nî lūn-bûn
@nan
1996年の論文
@ja
1996年論文
@yue
1996年論文
@zh-hant
1996年論文
@zh-hk
1996年論文
@zh-mo
1996年論文
@zh-tw
1996年论文
@wuu
1996年论文
@zh
1996年论文
@zh-cn
name
Insulin-mediated inhibition of ...... y cultures of rat hepatocytes.
@en
Insulin-mediated inhibition of ...... y cultures of rat hepatocytes.
@nl
type
label
Insulin-mediated inhibition of ...... y cultures of rat hepatocytes.
@en
Insulin-mediated inhibition of ...... y cultures of rat hepatocytes.
@nl
prefLabel
Insulin-mediated inhibition of ...... y cultures of rat hepatocytes.
@en
Insulin-mediated inhibition of ...... y cultures of rat hepatocytes.
@nl
P2093
P2860
P356
P1433
P1476
Insulin-mediated inhibition of ...... y cultures of rat hepatocytes.
@en
P2093
C E Sparks
J D Sparks
M Bolognino
P2860
P304
P356
10.1042/BJ3130567
P407
P478
313 ( Pt 2)
P577
1996-01-01T00:00:00Z