Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ
about
Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activityCD147 is a regulatory subunit of the gamma-secretase complex in Alzheimer's disease amyloid beta-peptide productionDealing with the family: CD147 interactions with cyclophilinsA novel form of the membrane protein CD147 that contains an extra Ig-like domain and interacts homophilicallyBasigin (CD147), a multifunctional transmembrane glycoprotein with various binding partnersHypoxia, cancer metabolism and the therapeutic benefit of targeting lactate/H(+) symportersBasigin (CD147) is the target for organomercurial inhibition of monocarboxylate transporter isoforms 1 and 4: the ancillary protein for the insensitive MCT2 is EMBIGIN (gp70)MCT1 and its accessory protein CD147 are differentially regulated by TSH in rat thyroid cellsThe inhibition of monocarboxylate transporter 2 (MCT2) by AR-C155858 is modulated by the associated ancillary proteinStudies on the DIDS-binding site of monocarboxylate transporter 1 suggest a homology model of the open conformation and a plausible translocation cycleJuvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane.Importance of N-glycosylation on CD147 for its biological functionsMutations in MCT8 in patients with Allan-Herndon-Dudley-syndrome affecting its cellular distributionExpression of extracellular matrix metalloproteinase inducer (EMMPRIN) and its related extracellular matrix degrading enzymes in the endometrium during estrous cycle and early gestation in cattle.Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure.Mechanisms regulating tissue-specific polarity of monocarboxylate transporters and their chaperone CD147 in kidney and retinal epitheliaProteomic identification of S-nitrosylated Golgi proteins: new insights into endothelial cell regulation by eNOS-derived NO.In situ analysis of spatial relationships between proteins of the nuclear pore complexThe monocarboxylate transporter family--Structure and functional characterization.The plasma membrane lactate transporter MCT4, but not MCT1, is up-regulated by hypoxia through a HIF-1alpha-dependent mechanism.Erythrocyte invasion receptors for Plasmodium falciparum: new and old.Evidence that CD147 modulation of beta-amyloid (Abeta) levels is mediated by extracellular degradation of secreted AbetaModulation of MCT3 expression during wound healing of the retinal pigment epithelium.The neuroplastin adhesion molecules are accessory proteins that chaperone the monocarboxylate transporter MCT2 to the neuronal cell surface.Transport activity of the high-affinity monocarboxylate transporter MCT2 is enhanced by extracellular carbonic anhydrase IV but not by intracellular carbonic anhydrase IIJunction protein shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147.5A11/Basigin gene products are necessary for proper maturation and function of the retina.CD147 immunoglobulin superfamily receptor function and role in pathologyUnassembled CD147 is an endogenous endoplasmic reticulum-associated degradation substrateEmmprin (basigin/CD147): matrix metalloproteinase modulator and multifunctional cell recognition molecule that plays a critical role in cancer progression.The anti-tumour agent lonidamine is a potent inhibitor of the mitochondrial pyruvate carrier and plasma membrane monocarboxylate transporters.Overview of the proton-coupled MCT (SLC16A) family of transporters: characterization, function and role in the transport of the drug of abuse gamma-hydroxybutyric acid.Hyaluronan, CD44 and Emmprin: partners in cancer cell chemoresistance.Monocarboxylate transporters in the brain and in cancer.CD147 regulates the expression of MCT1 and lactate export in multiple myeloma cells.Intracellular and extracellular carbonic anhydrases cooperate non-enzymatically to enhance activity of monocarboxylate transporters.CD147: a small molecule transporter ancillary protein at the crossroad of multiple hallmarks of cancer and metabolic reprogramming.Cyclophilin-CD147 interactions: a new target for anti-inflammatory therapeutics.Basigin: a multifunctional membrane protein with an emerging role in infections by malaria parasites.
P2860
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P2860
Fluorescence resonance energy transfer studies on the interaction between the lactate transporter MCT1 and CD147 provide information on the topology and stoichiometry of the complex in situ
description
2002 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2002
@ast
im Februar 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/02/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/02/01)
@nl
наукова стаття, опублікована в лютому 2002
@uk
name
Fluorescence resonance energy ...... iometry of the complex in situ
@ast
Fluorescence resonance energy ...... iometry of the complex in situ
@en
Fluorescence resonance energy ...... iometry of the complex in situ
@nl
type
label
Fluorescence resonance energy ...... iometry of the complex in situ
@ast
Fluorescence resonance energy ...... iometry of the complex in situ
@en
Fluorescence resonance energy ...... iometry of the complex in situ
@nl
prefLabel
Fluorescence resonance energy ...... iometry of the complex in situ
@ast
Fluorescence resonance energy ...... iometry of the complex in situ
@en
Fluorescence resonance energy ...... iometry of the complex in situ
@nl
P356
P1476
Fluorescence resonance energy ...... iometry of the complex in situ
@en
P2093
David Meredith
Marieangela C Wilson
P304
P356
10.1074/JBC.M109658200
P407
P577
2001-11-21T00:00:00Z