Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells
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Phosphorylation-mediated regulation of alternative splicing in cancerProteasome-mediated proteolysis of SRSF5 splicing factor intriguingly co-occurs with SRSF5 mRNA upregulation during late erythroid differentiationRegulation of vascular endothelial growth factor (VEGF) splicing from pro-angiogenic to anti-angiogenic isoforms: a novel therapeutic strategy for angiogenesisMolecular and genetic studies imply Akt-mediated signaling promotes protein kinase CbetaII alternative splicing via phosphorylation of serine/arginine-rich splicing factor SRp40Akt2 regulation of Cdc2-like kinases (Clk/Sty), serine/arginine-rich (SR) protein phosphorylation, and insulin-induced alternative splicing of PKCbetaII messenger ribonucleic acidDifferential transcriptional and posttranslational transcription factor 7-like regulation among nondiabetic individuals and type 2 diabetic patients.Survival advantages conferred to colon cancer cells by E-selectin-induced activation of the PI3K-NFκB survival axis downstream of Death receptor-3.Vitamin A metabolite, all-trans-retinoic acid, mediates alternative splicing of protein kinase C deltaVIII (PKCdeltaVIII) isoform via splicing factor SC35.Exonic splicing enhancer-dependent selection of the bovine papillomavirus type 1 nucleotide 3225 3' splice site can be rescued in a cell lacking splicing factor ASF/SF2 through activation of the phosphatidylinositol 3-kinase/Akt pathway.Clk/STY (cdc2-like kinase 1) and Akt regulate alternative splicing and adipogenesis in 3T3-L1 pre-adipocytesLong Non-Coding RNA NEAT1 Associates with SRp40 to Temporally Regulate PPARγ2 Splicing during Adipogenesis in 3T3-L1 Cells.Tissue stiffness regulates serine/arginine-rich protein-mediated splicing of the extra domain B-fibronectin isoform in tumorsThe Alternative Splicing of Cytoplasmic Polyadenylation Element Binding Protein 2 Drives Anoikis Resistance and the Metastasis of Triple Negative Breast Cancer.Adipose tissue TCF7L2 splicing is regulated by weight loss and associates with glucose and fatty acid metabolism.Specific protein kinase C isoforms as transducers and modulators of insulin signalingCeramide-activated protein phosphatase involvement in insulin resistance via Akt, serine/arginine-rich protein 40, and ribonucleic acid splicing in L6 skeletal muscle cellsGlobal analysis of alternative splicing regulation by insulin and wingless signaling in Drosophila cellsProtein kinase C-delta (PKC-delta ) is activated by type I interferons and mediates phosphorylation of Stat1 on serine 727.Global analysis of physical and functional RNA targets of hnRNP L reveals distinct sequence and epigenetic features of repressed and enhanced exons.The Regulation of TGFβ1 Induced Fibronectin EDA Exon Alternative Splicing in Human Renal Proximal Tubule Epithelial Cells.Antagonistic SR proteins regulate alternative splicing of tumor-related Rac1b downstream of the PI3-kinase and Wnt pathways.Combinatorial control of signal-induced exon repression by hnRNP L and PSF.PKCdelta alternatively spliced isoforms modulate cellular apoptosis in retinoic acid-induced differentiation of human NT2 cells and mouse embryonic stem cells.Measles virus induces expression of SIP110, a constitutively membrane clustered lipid phosphatase, which inhibits T cell proliferation.Alternatively spliced lipin isoforms exhibit distinct expression pattern, subcellular localization, and role in adipogenesis.Regulation of GLUT1-mediated glucose uptake by PKClambda-PKCbeta(II) interactions in 3T3-L1 adipocytes.Inhibition of phosphatidylinositol 3-kinase- and ERK MAPK-regulated protein synthesis reveals the pro-apoptotic properties of CD40 ligation in carcinoma cells.Identification of cells deficient in signaling-induced alternative splicing by use of somatic cell genetics.The protein kinase C beta II exon confers mRNA instability in the presence of high glucose concentrations.Developmentally spliced PKCbetaII provides a possible link between mTORC2 and Akt kinase to regulate 3T3-L1 adipocyte insulin-stimulated glucose transport.Protein kinase C δ (PKCδ) splice variants modulate apoptosis pathway in 3T3L1 cells during adipogenesis: identification of PKCδII inhibitor.Arachidonic acid inhibits the insulin induction of glucose-6-phosphate dehydrogenase via p38 MAP kinase.Signaling Pathways Driving Aberrant Splicing in Cancer Cells.Alternative-splicing defects in cancer: Splicing regulators and their downstream targets, guiding the way to novel cancer therapeutics.Trans-Ethnic Mapping of Identifies Two Independent SLE-Risk Linkage Groups Enriched for Co-Transcriptional Splicing MarksSplicing in the RNA World
P2860
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P2860
Insulin regulates alternative splicing of protein kinase C beta II through a phosphatidylinositol 3-kinase-dependent pathway involving the nuclear serine/arginine-rich splicing factor, SRp40, in skeletal muscle cells
description
2001 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի հունիսին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2001
@ast
im Juni 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/06/22)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/06/22)
@nl
наукова стаття, опублікована в червні 2001
@uk
name
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@ast
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@en
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@nl
type
label
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@ast
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@en
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@nl
prefLabel
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@ast
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@en
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@nl
P2093
P2860
P356
P1476
Insulin regulates alternative ...... Rp40, in skeletal muscle cells
@en
P2093
C. E. Chalfant
D. C. Eichler
D. R. Cooper
J. E. Watson
J. R. Wyatt
N. A. Patel
N. M. Dean
P2860
P304
22648–22654
P356
10.1074/JBC.M101260200
P407
P577
2001-06-22T00:00:00Z