Functional properties of internalization-deficient P2X4 receptors reveal a novel mechanism of ligand-gated channel facilitation by ivermectin
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Molecular and functional properties of P2X receptors--recent progress and persisting challengesTwo open states of P2X receptor channelsBrain-derived neurotrophic factor from microglia: a molecular substrate for neuropathic painP2X4 receptors mediate PGE2 release by tissue-resident macrophages and initiate inflammatory painNicotinic acetylcholine receptor alpha7 subunits with a C2 cytoplasmic loop yellow fluorescent protein insertion form functional receptors.Imaging P2X4 receptor subcellular distribution, trafficking, and regulation using P2X4-pHluorinContribution of P2X4 receptors to ethanol intake in male C57BL/6 mice.P2X4 Receptor Function in the Nervous System and Current Breakthroughs in Pharmacology.P2X4 receptors in activated C8-B4 cells of cerebellar microglial origin.Ivermectin antagonizes ethanol inhibition in purinergic P2X4 receptorsBasolateral P2X₄channels stimulate ENaC activity in Xenopus cortical collecting duct A6 cells.Identification of functionally important residues of the rat P2X4 receptor by alanine scanning mutagenesis of the dorsal fin and left flipper domains.Ivermectin-dependent release of IL-1beta in response to ATP by peritoneal macrophages from P2X(7)-KO mice.Cross-talk between P2X4 and gamma-aminobutyric acid, type A receptors determines synaptic efficacy at a central synapse.Activation and regulation of purinergic P2X receptor channelsAllosteric modulation of purine and pyrimidine receptors.Allosteric regulation of the P2X4 receptor channel pore dilationAllosteric modulation of ATP-gated P2X receptor channelsPhosphoinositides regulate P2X4 ATP-gated channels through direct interactions.Agonist-dependent endocytosis of γ-aminobutyric acid type A (GABAA) receptors revealed by a γ2(R43Q) epilepsy mutation.P2X-mediated AMPA receptor internalization and synaptic depression is controlled by two CaMKII phosphorylation sites on GluA1 in hippocampal neurons.Subtype-specific regulation of P2X3 and P2X2/3 receptors by phosphoinositides in peripheral nociceptors.Functional evidence for the expression of P2X1, P2X4 and P2X7 receptors in human lung mast cells.ATP receptors gate microglia signaling in neuropathic pain.P2X4 purinoceptor signaling in chronic pain.Roles of conserved ectodomain cysteines of the rat P2X4 purinoreceptor in agonist binding and channel gating.Modulation of Central Synapses by Astrocyte-Released ATP and Postsynaptic P2X Receptors.Protein kinase A regulation of P2X(4) receptors: requirement for a specific motif in the C-terminus.Role of aromatic and charged ectodomain residues in the P2X(4) receptor functions.Deciphering the regulation of P2X4 receptor channel gating by ivermectin using Markov models.Morphine enhances IL-1β release through toll-like receptor 4-mediated endocytic pathway in microglia.Distinct contributions by ionotropic purinoceptor subtypes to ATP-evoked calcium signals in mouse parotid acinar cells.Shear stress modulates endothelial KLF2 through activation of P2X4.Rab5 regulates internalisation of P2X4 receptors and potentiation by ivermectin.P2X4 receptors control the fate and survival of activated microglia.Secretion of IL-1β triggered by dynasore in murine peritoneal macrophages.P2X4 receptor channels form large noncytolytic pores in resting and activated microglia.
P2860
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P2860
Functional properties of internalization-deficient P2X4 receptors reveal a novel mechanism of ligand-gated channel facilitation by ivermectin
description
2006 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
scientific journal article
@en
vedecký článok (publikovaný 2006/02/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/02/01)
@nl
наукова стаття, опублікована в лютому 2006
@uk
مقالة علمية (نشرت في فبراير 2006)
@ar
name
Functional properties of inter ...... nel facilitation by ivermectin
@ast
Functional properties of inter ...... nel facilitation by ivermectin
@en
Functional properties of inter ...... nel facilitation by ivermectin
@nl
type
label
Functional properties of inter ...... nel facilitation by ivermectin
@ast
Functional properties of inter ...... nel facilitation by ivermectin
@en
Functional properties of inter ...... nel facilitation by ivermectin
@nl
prefLabel
Functional properties of inter ...... nel facilitation by ivermectin
@ast
Functional properties of inter ...... nel facilitation by ivermectin
@en
Functional properties of inter ...... nel facilitation by ivermectin
@nl
P2093
P3181
P356
P1476
Functional properties of inter ...... nel facilitation by ivermectin
@en
P2093
Estelle Toulmé
Florentina Soto
Maurice Garret
P304
P3181
P356
10.1124/MOL.105.018812
P577
2005-11-10T00:00:00Z