Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages
about
Prenatal Exposure to DEHP Affects Spermatogenesis and Sperm DNA Methylation in a Strain-Dependent MannerMechanistic considerations for human relevance of cancer hazard of di(2-ethylhexyl) phthalateMapping gene expression changes in the fetal rat testis following acute dibutyl phthalate exposure defines a complex temporal cascade of responding cell typesSpecies-specific dibutyl phthalate fetal testis endocrine disruption correlates with inhibition of SREBP2-dependent gene expression pathwaysMolecular mechanisms mediating the effect of mono-(2-ethylhexyl) phthalate on hormone-stimulated steroidogenesis in MA-10 mouse tumor Leydig cellsComponents of plastic: experimental studies in animals and relevance for human health.In vitro acute exposure to DEHP affects oocyte meiotic maturation, energy and oxidative stress parameters in a large animal modelMono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.Age- and species-dependent infiltration of macrophages into the testis of rats and mice exposed to mono-(2-Ethylhexyl) phthalate (MEHP).Genomic biomarkers of phthalate-induced male reproductive developmental toxicity: a targeted RT-PCR array approach for defining relative potency.Gender-Specific Adverse Effects of Mono-Ethylhexyl Phthalate on Steroidogenesis in Immature Granulosa Cells and Rat Leydig cell Progenitors in vitro.Mono-(2-ethylhexyl)-phthalate (MEHP) affects ERK-dependent GDNF signalling in mouse stem-progenitor spermatogonia.Mono-2-ethylhexyl phthalate stimulates androgen production but suppresses mitochondrial function in mouse leydig cells with different steroidogenic potential.Cross-talk between the Akt and NF-kappaB signaling pathways inhibits MEHP-induced germ cell apoptosis.Improving in vitro Sertoli cell/gonocyte co-culture model for assessing male reproductive toxicity: Lessons learned from comparisons of cytotoxicity versus genomic responses to phthalates.Di-(2 ethylhexyl) phthalate and flutamide alter gene expression in the testis of immature male rats.Phthalate metabolism and kinetics in an in vitro model of testis development.Developmental toxicity testing for safety assessment: new approaches and technologies.Human testis steroidogenesis is inhibited by phthalates.In silico pathway analysis: the final frontier towards completely rational drug design.Role of phospholipase D in regulation of testicular Leydig cell hyperplasia in Sprague-Dawley rats treated with di(2-ethylhexyl) phthalate.Di(2-ethylhexyl) phthalate (DEHP) increases transforming growth factor-beta1 expression in fetal mouse genital tubercles.
P2860
Q27303092-5865000C-77BD-40AF-BB61-29466DD70849Q28256111-57E73F0E-BA82-4B9C-B3FA-5833E7A8DB18Q28571521-A98C66EC-B4DE-42E9-9106-D4281C8C6FADQ30427695-900BACFF-1582-4F8C-BB1C-083C5ABB4647Q30495487-F53B82E9-9814-4D52-91D0-284CC09AA488Q33862225-98B11606-FD41-4152-B88A-9511F7D23825Q34072732-9ACFC0A1-F123-4601-9F3A-5EB10655E072Q34075536-A09AF64E-FCDA-4B31-887A-150A9E8146A9Q35617225-679F6210-30B6-433C-9CA8-8E0EE750AA98Q35685384-BB52F847-2116-412D-B3B2-6129E15E1D1BQ35971120-ABBBDEEB-3053-4DF3-BE96-638DFAA595B1Q36040706-FCA22C45-C8AB-4623-8FA2-DC1F9977610EQ36801750-01885BE0-0672-452A-BC4C-531A058D0655Q36968719-F2E0BD09-B65C-4A07-B584-084906E4A476Q37327557-EEC77083-A61C-4561-AA47-6B55756E5713Q37384183-7FA16FA5-9680-4915-A434-9A7FD5797754Q37540902-48071FC8-EAED-42E9-AD81-9BF4481CF4ADQ37902621-6C60EF75-BF09-4EA9-BC7E-34D14C4F44A4Q39383132-2A4ECF45-361D-42D8-AFCE-A1D710F552BCQ40064969-B461BE22-5F1D-4447-96B0-57B70B6FF8B5Q42810843-E0A644E5-2FD0-4A12-B81F-5754F4DA459AQ46441149-545EF1A9-48CF-4858-AE67-580F70D2C464
P2860
Testicular gene expression profiling following prepubertal rat mono-(2-ethylhexyl) phthalate exposure suggests a common initial genetic response at fetal and prepubertal ages
description
2006 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im Oktober 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/10/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/10/01)
@nl
наукова стаття, опублікована в жовтні 2006
@uk
مقالة علمية (نشرت في أكتوبر 2006)
@ar
name
Testicular gene expression pro ...... at fetal and prepubertal ages
@ast
Testicular gene expression pro ...... at fetal and prepubertal ages
@en
Testicular gene expression pro ...... at fetal and prepubertal ages
@nl
type
label
Testicular gene expression pro ...... at fetal and prepubertal ages
@ast
Testicular gene expression pro ...... at fetal and prepubertal ages
@en
Testicular gene expression pro ...... at fetal and prepubertal ages
@nl
prefLabel
Testicular gene expression pro ...... at fetal and prepubertal ages
@ast
Testicular gene expression pro ...... at fetal and prepubertal ages
@en
Testicular gene expression pro ...... at fetal and prepubertal ages
@nl
P2093
P356
P1476
Testicular gene expression pro ...... at fetal and prepubertal ages
@en
P2093
Delong Liu
Duncan G. Wallace
Kamin J. Johnson
Kevin W. Gaido
Stephanie A. Lahousse
P304
P356
10.1093/TOXSCI/KFL049
P577
2006-10-01T00:00:00Z