A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
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Centrosome dysfunction contributes to chromosome instability, chromoanagenesis, and genome reprograming in cancerSIK2 is a centrosome kinase required for bipolar mitotic spindle formation that provides a potential target for therapy in ovarian cancerCasein kinase 1 delta functions at the centrosome to mediate Wnt-3a-dependent neurite outgrowthDDX3 regulates cell growth through translational control of cyclin E1A novel role of human holliday junction resolvase GEN1 in the maintenance of centrosome integrityPolo box domain of Plk3 functions as a centrosome localization signal, overexpression of which causes mitotic arrest, cytokinesis defects, and apoptosisConserved motif of CDK5RAP2 mediates its localization to centrosomes and the Golgi complexAb ovo or de novo? Mechanisms of centriole duplicationEstrogen regulation of cyclin E2 requires cyclin D1 but not c-MycThe function and molecular mechnism of cyclin Y proteinHEF1-aurora A interactions: points of dialog between the cell cycle and cell attachment signaling networksThe structure of cyclin E1/CDK2: implications for CDK2 activation and CDK2-independent rolesMolecular basis for viral selective replication in cancer cells: activation of CDK2 by adenovirus-induced cyclin ECep57, a multidomain protein with unique microtubule and centrosomal localization domainsCharacterization of centrosomal association of nucleophosmin/B23 linked to Crm1 activityTargeting of Nphp3 to the primary cilia is controlled by an N-terminal myristoylation site and coiled-coil domainsDrug targets for cell cycle dysregulators in leukemogenesis: in silico docking studiesPioneering the Xenopus oocyte and egg extract system.Cell cycle regulators control centrosome elimination during oogenesis in Caenorhabditis elegans.Cell cycle-dependent localization of CHK2 at centrosomes during mitosis.An ATM- and ATR-dependent checkpoint inactivates spindle assembly by targeting CEP63.Localization of TEIF in the centrosome and its functional association with centrosome amplification in DNA damage, telomere dysfunction and human cancers.Pericentrin in cellular function and diseaseDistinct and redundant functions of cyclin E1 and cyclin E2 in development and cancerDiscovery of a distinct domain in cyclin A sufficient for centrosomal localization independently of Cdk binding.A CULLINary ride across the secretory pathway: more than just secretion.Cyclin E deregulation impairs mitotic progression through premature activation of Cdc25C.New roles of cyclin D1.The 19q12 bladder cancer GWAS signal: association with cyclin E function and aggressive diseaseCentrosomal localization of cyclins E and A: structural similarities and functional differencesMolecular Approach to Uterine Leiomyosarcoma: LMP2-Deficient Mice as an Animal Model of Spontaneous Uterine Leiomyosarcoma.Nde1-mediated inhibition of ciliogenesis affects cell cycle re-entry.Cdk2 is required for breast cancer mediated by the low-molecular-weight isoform of cyclin EMammalian cell-cycle regulation: several Cdks, numerous cyclins and diverse compensatory mechanisms.p53: guardian of ploidySteroidogenic Factor 1 (NR5A1) resides in centrosomes and maintains genomic stability by controlling centrosome homeostasis.Involvement of proteasome β1i subunit, LMP2, on development of uterin leiomyosarcma.Transcriptome Signature and Regulation in Human Somatic Cell Reprogramming.Characterization of BRCA1 protein targeting, dynamics, and function at the centrosome: a role for the nuclear export signal, CRM1, and Aurora A kinase.Loss of cyclin-dependent kinase 2 (CDK2) inhibitory phosphorylation in a CDK2AF knock-in mouse causes misregulation of DNA replication and centrosome duplication.
P2860
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P2860
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
description
2004 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Science
@fr
artículu científicu espublizáu en 2004
@ast
im Oktober 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/10/29)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/10/29)
@nl
наукова стаття, опублікована в жовтні 2004
@uk
name
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@ast
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@en
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@nl
type
label
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@ast
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@en
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@nl
prefLabel
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@ast
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@en
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@nl
P3181
P356
P1433
P1476
A centrosomal localization signal in cyclin E required for Cdk2-independent S phase entry
@en
P2093
James L. Maller
Yutaka Matsumoto
P304
P3181
P356
10.1126/SCIENCE.1103544
P407
P577
2004-10-29T00:00:00Z