Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways - Wikidata - wikimedia - TriplyDB

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways

http://www.wikidata.org/entity/Q28579410

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α7 nicotinic ACh receptors as a ligand-gated source of Ca(2+) ions: the search for a Ca(2+) optimum Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease In vivo evaluation of alpha7 nicotinic acetylcholine receptor agonists [11C]A-582941 and [11C]A-844606 in mice and conscious monkeys Differential immediate and sustained memory enhancing effects of alpha7 nicotinic receptor agonists and allosteric modulators in rats Translating the frontiers of brain repair to treatments: starting not to break the rules nAChR dysfunction as a common substrate for schizophrenia and comorbid nicotine addiction: Current trends and perspectives.Nicotinic ligands as multifunctional agents for the treatment of neuropsychiatric disorders R-(+) and S-(-) isomers of cotinine augment cholinergic responses in vitro and in vivo.Augmentation of cognitive function by NS9283, a stoichiometry-dependent positive allosteric modulator of α2- and α4-containing nicotinic acetylcholine receptors.Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia TC-5619: an alpha7 neuronal nicotinic receptor-selective agonist that demonstrates efficacy in animal models of the positive and negative symptoms and cognitive dysfunction of schizophrenia.The Concise Guide to PHARMACOLOGY 2013/14: ligand-gated ion channels.Nicotinic acetylcholine receptor signalling: roles in Alzheimer's disease and amyloid neuroprotection.Prefrontal beta2 subunit-containing and alpha7 nicotinic acetylcholine receptors differentially control glutamatergic and cholinergic signaling A new IRAK-M-mediated mechanism implicated in the anti-inflammatory effect of nicotine via α7 nicotinic receptors in human macrophages.Role of alpha7 nicotinic acetylcholine receptor in calcium signaling induced by prion protein interaction with stress-inducible protein 1.Modes and models of forebrain cholinergic neuromodulation of cognition.Role of neuronal nicotinic acetylcholine receptors (nAChRs) on learning and memory in zebrafish.α7 Nicotinic Receptor Agonists: Potential Therapeutic Drugs for Treatment of Cognitive Impairments in Schizophrenia and Alzheimer's Disease.Pharmacological enhancement of memory and executive functioning in laboratory animals.Preclinical characterization of A-582941: a novel alpha7 neuronal nicotinic receptor agonist with broad spectrum cognition-enhancing properties.An experimental study on (131)I-CHIBA-1001: a radioligand for α7 nicotinic acetylcholine receptors.A type-II positive allosteric modulator of α7 nAChRs reduces brain injury and improves neurological function after focal cerebral ischemia in rats.Positive allosteric modulators as an approach to nicotinic acetylcholine receptor-targeted therapeutics: advantages and limitations.CREB1 Genotype Modulates Adaptive Reward-Based Decisions in Humans.Mammillary Bodies in Alzheimer's Disease: A Golgi and Electron Microscope Study.Alpha7 nicotinic acetylcholine receptors modulate motivation to self-administer nicotine: implications for smoking and schizophrenia.Reduced Chrna7 expression in mice is associated with decreases in hippocampal markers of inhibitory function: implications for neuropsychiatric diseases.Neurotransmitter receptors and cognitive dysfunction in Alzheimer's disease and Parkinson's disease.L-3-n-butylphthalide Rescues Hippocampal Synaptic Failure and Attenuates Neuropathology in Aged APP/PS1 Mouse Model of Alzheimer's Disease.The Novel, Nicotinic Alpha7 Receptor Partial Agonist, BMS-933043, Improves Cognition and Sensory Processing in Preclinical Models of Schizophrenia.The effect of α7 nicotinic receptor activation on glutamatergic transmission in the hippocampus.Nicotine recruits glutamate receptors to postsynaptic sites.Alpha-7 nicotinic agonists for cognitive deficits in neuropsychiatric disorders: A translational meta-analysis of rodent and human studies.Identification and in vitro pharmacological characterization of a novel and selective α7 nicotinic acetylcholine receptor agonist, Br-IQ17B.Neuroprotective and cognitive-enhancing effects of the combined extract of Cyperus rotundus and Zingiber officinale.Pro-cognitive activity in rats of 3-furan-2-yl-N-p-tolyl-acrylamide, a positive allosteric modulator of the α7 nicotinic acetylcholine receptor Epinephrine and glucose modulate training-related CREB phosphorylation in old rats: relationships to age-related memory impairments.Effects of nicotinic acetylcholine receptor agonists on cognition in rhesus monkeys with a chronic cocaine self-administration history.Nicotinic alpha7- or beta2-containing receptor knockout: effects on radial-arm maze learning and long-term nicotine consumption in mice.

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Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways

http://www.wikidata.org/entity/Q28579410

description

2007 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած

@hyw

2007 թվականի սեպտեմբերին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2007

@ast

im September 2007 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2007/09/26)

@sk

vědecký článek publikovaný v roce 2007

@cs

wetenschappelijk artikel (gepubliceerd op 2007/09/26)

@nl

наукова стаття, опублікована у вересні 2007

@uk

مقالة علمية (نشرت في 26-9-2007)

@ar

name

Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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type

label

Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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prefLabel

Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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JNEUROSCI.2444-07.2007

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Journal of Neuroscience

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Broad-spectrum efficacy across ...... CREB phosphorylation pathways

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P2093

Arthur L Nikkel

http://www.w3.org/2001/XMLSchema#string

Clark A Briggs

http://www.w3.org/2001/XMLSchema#string

Daniel Timmermann

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David J Anderson

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Earl Gubbins

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Holly M Robb

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James P Sullivan

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Jennifer M Frost

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Jens Halvard Gronlien

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Jerry Buccafusco

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10578-10587

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scholarly article

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4263742

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10.1523/JNEUROSCI.2444-07.2007

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39

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2007-09-26T00:00:00Z

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17898229

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Cholinergic receptor, nicotinic, alpha polypeptide 7

Cholinergic receptor nicotinic alpha 7 subunit

phosphorylation

response to acetylcholine

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6673141

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