Mitochondrial localization of APE/Ref-1 in thyroid cells
about
Identification and characterization of mitochondrial targeting sequence of human apurinic/apyrimidinic endonuclease 1APE1/Ref-1 interacts with NPM1 within nucleoli and plays a role in the rRNA quality control process.Dynamic Regulation of APE1/Ref-1 as a Therapeutic Target ProteinNucleolar accumulation of APE1 depends on charged lysine residues that undergo acetylation upon genotoxic stress and modulate its BER activity in cellsTranscriptional regulatory functions of mammalian AP-endonuclease (APE1/Ref-1), an essential multifunctional protein.Critical lysine residues within the overlooked N-terminal domain of human APE1 regulate its biological functions.The many functions of APE1/Ref-1: not only a DNA repair enzymeEffect of caloric restriction on base-excision repair (BER) in the aging rat brainMembrane association of mitochondrial DNA facilitates base excision repair in mammalian mitochondria.A comparative proteomic strategy for subcellular proteome research: ICAT approach coupled with bioinformatics prediction to ascertain rat liver mitochondrial proteins and indication of mitochondrial localization for catalase.Dynamic compartmentalization of DNA repair proteins within spiral ganglion neurons in response to noise stress.Identification and characterization of mitochondrial abasic (AP)-endonuclease in mammalian cells.Knock-in reconstitution studies reveal an unexpected role of Cys-65 in regulating APE1/Ref-1 subcellular trafficking and functionBcl2 inhibition of mitochondrial DNA repair.Mitochondrial translocation of APE1 relies on the MIA pathway.Subcellular localization of APE1/Ref-1 in human hepatocellular carcinoma: possible prognostic significance.Oxidative genome damage and its repair: implications in aging and neurodegenerative diseases.Increased human AP endonuclease 1 level confers protection against the paternal age effect in mice.Age-related instability in spermatogenic cell nuclear and mitochondrial DNA obtained from Apex1 heterozygous mice.Mitochondrial DNA, base excision repair and neurodegeneration.Inhibition of apurinic/apyrimidinic endonuclease I's redox activity revisited.Mitochondrial DNA damage is associated with reduced mitochondrial bioenergetics in Huntington's disease.Human apurinic/apyrimidinic endonuclease 1.Understanding different functions of mammalian AP endonuclease (APE1) as a promising tool for cancer treatment.A matter of life, death and diseases: mitochondria from a proteomic perspective.Functional regulation of the apurinic/apyrimidinic endonuclease 1 by nucleophosmin: impact on tumor biology.Redox factor-1 mediates NF-kappaB nuclear translocation for LPS-induced iNOS expression in murine macrophage cell line RAW 264.7.Redox factor-1: an extra-nuclear role in the regulation of endothelial oxidative stress and apoptosis.A novel interaction between DNA ligase III and DNA polymerase gamma plays an essential role in mitochondrial DNA stability.Mitochondrial nucleases ENDOG and EXOG participate in mitochondrial DNA depletion initiated by herpes simplex virus 1 UL12.5.Altered intracellular redox status in Gaucher disease fibroblasts and impairment of adaptive response against oxidative stress.Mitochondrial DNA damage and the involvement of antioxidant defense and repair system in hippocampi of rats with chronic seizures.Age-dependent decline of DNA repair activity for oxidative lesions in rat brain mitochondria.The Role of DNA Repair in Maintaining Mitochondrial DNA Stability.Prognostic significance of APE1 cytoplasmic localization in human epithelial ovarian cancer.Mitochondrial DNA mutations in differentiated thyroid cancer with respect to the age factor.
P2860
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P2860
Mitochondrial localization of APE/Ref-1 in thyroid cells
description
2001 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2001 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2001
@ast
im März 2001 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2001/03/07)
@sk
vědecký článek publikovaný v roce 2001
@cs
wetenschappelijk artikel (gepubliceerd op 2001/03/07)
@nl
наукова стаття, опублікована в березні 2001
@uk
مقالة علمية (نشرت في 7-3-2001)
@ar
name
Mitochondrial localization of APE/Ref-1 in thyroid cells
@ast
Mitochondrial localization of APE/Ref-1 in thyroid cells
@en
Mitochondrial localization of APE/Ref-1 in thyroid cells
@nl
type
label
Mitochondrial localization of APE/Ref-1 in thyroid cells
@ast
Mitochondrial localization of APE/Ref-1 in thyroid cells
@en
Mitochondrial localization of APE/Ref-1 in thyroid cells
@nl
prefLabel
Mitochondrial localization of APE/Ref-1 in thyroid cells
@ast
Mitochondrial localization of APE/Ref-1 in thyroid cells
@en
Mitochondrial localization of APE/Ref-1 in thyroid cells
@nl
P2093
P3181
P1433
P1476
Mitochondrial localization of APE/Ref-1 in thyroid cells
@en
P2093
A. Bandiera
C. Di Loreto
C. Pucillo
E. Crivellato
G. Damante
G. Manzini
M. R. Kelley
P304
P3181
P356
10.1016/S0921-8777(00)00068-9
P407
P577
2001-03-07T00:00:00Z