Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
about
Crystal structure of the human K2P TRAAK, a lipid- and mechano-sensitive K+ ion channelRegulation of two-pore-domain (K2P) potassium leak channels by the tyrosine kinase inhibitor genisteinTemperature sensitivity of two-pore (K2P) potassium channelsCold hypersensitivity increases with age in mice with sickle cell diseaseDomain-swapped chain connectivity and gated membrane access in a Fab-mediated crystal of the human TRAAK K+ channel.Two-pore Domain Potassium Channels in AstrocytesDistribution of two-pore-domain potassium channels in the adult rat vestibular peripheryThe mechano-activated K+ channels TRAAK and TREK-1 control both warm and cold perception.Control of Phasic Firing by a Background Leak Current in Avian Forebrain Auditory Neurons.Molecular mechanisms of temperature adaptationPolymodal activation of the TREK-2 K2P channel produces structurally distinct open statesIon channel profile of TRPM8 cold receptors reveals a role of TASK-3 potassium channels in thermosensation.Expression of transient receptor potential channels and two-pore potassium channels in subtypes of vagal afferent neurons in rat2,2,2-trichloroethanol activates a nonclassical potassium channel in cerebrovascular smooth muscle and dilates the middle cerebral artery.Phenotyping sensory nerve endings in vitro in the mouse.Topical application of L-menthol induces heat analgesia, mechanical allodynia, and a biphasic effect on cold sensitivity in rats.Dominant negative effects of a non-conducting TREK1 splice variant expressed in brain.Mechanosensory neurons, cutaneous mechanoreceptors, and putative mechanoproteins.The influence of cold temperature on cellular excitability of hippocampal networksControl of somatic membrane potential in nociceptive neurons and its implications for peripheral nociceptive transmission.Structural models of TREK channels and their gating mechanism.The effect of pH and ion channel modulators on human placental arteries.Modulation of TRESK background K+ channel by membrane stretchTransmembrane helix straightening and buckling underlies activation of mechanosensitive and thermosensitive K(2P) channels.TRESK channel contribution to nociceptive sensory neurons excitability: modulation by nerve injury.Colitis decreases mechanosensitive K2P channel expression and function in mouse colon sensory neuronsDifferential sensitivity of TREK-1, TREK-2 and TRAAK background potassium channels to the polycationic dye ruthenium red.Multiple modalities converge on a common gate to control K2P channel function.Transient receptor potential cation channel, subfamily C, member 5 (TRPC5) is a cold-transducer in the peripheral nervous system.Molecular regulations governing TREK and TRAAK channel functions.Expression of two-pore domain potassium channels in nonhuman primate sperm.Leak K⁺ channel mRNAs in dorsal root ganglia: relation to inflammation and spontaneous pain behaviourA unique alkaline pH-regulated and fatty acid-activated tandem pore domain potassium channel (K₂P) from a marine sponge.Thermosensitive transient receptor potential (TRP) channel agonists and their role in mechanical, thermal and nociceptive sensations as assessed using animal models.Selective Small Molecule Activators of TREK-2 Channels Stimulate Dorsal Root Ganglion c-Fiber Nociceptor Two-Pore-Domain Potassium Channel Currents and Limit Calcium Influx.Behavioral characterization of mice lacking Trek channels.The molecular and cellular basis of cold sensation.Mixing and matching TREK/TRAAK subunits generate heterodimeric K2P channels with unique properties.Heterodimerization within the TREK channel subfamily produces a diverse family of highly regulated potassium channels.Enhanced Expression of TREK-1 Is Related with Chronic Constriction Injury of Neuropathic Pain Mouse Model in Dorsal Root Ganglion
P2860
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P2860
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
description
2005 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2005 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2005
@ast
im April 2005 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2005/04/01)
@sk
vědecký článek publikovaný v roce 2005
@cs
wetenschappelijk artikel (gepubliceerd op 2005/04/01)
@nl
наукова стаття, опублікована у квітні 2005
@uk
مقالة علمية (نشرت في أبريل 2005)
@ar
name
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@ast
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@en
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@nl
type
label
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@ast
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@en
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@nl
prefLabel
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@ast
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@en
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@nl
P2093
P2860
P3181
P1476
Thermosensitivity of the two-pore domain K+ channels TREK-2 and TRAAK
@en
P2093
Changyong Choe
Dawon Kang
Donghee Kim
P2860
P304
P3181
P356
10.1113/JPHYSIOL.2004.081059
P407
P577
2005-04-01T00:00:00Z