A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism
about
Targeting amino acid metabolism in cancer growth and anti-tumor immune responseMYC, Metabolism, and CancerMYC and metabolism on the path to cancerMYC and the art of microRNA maintenanceSerine and glycine metabolism in cancerGenetically-defined metabolic reprogramming in cancerGenetic interaction between a chaperone of small nucleolar ribonucleoprotein particles and cytosolic serine hydroxymethyltransferase.c-Myc is a universal amplifier of expressed genes in lymphocytes and embryonic stem cellsThe oncogene c-Myc coordinates regulation of metabolic networks to enable rapid cell cycle entryThe myc road to hearing restoration.Widespread genomic instability mediated by a pathway involving glycoprotein Ib alpha and Aurora B kinase.Global regulation of nucleotide biosynthetic genes by c-MycOne-carbon metabolism and nucleotide biosynthesis as attractive targets for anticancer therapy.Interactions among mitochondrial proteins altered in glioblastoma.Measurement of glycine in the human brain in vivo by 1H-MRS at 3 T: application in brain tumorsDetermining PTEN functional status by network component deduced transcription factor activitiesThe Mad and Myc basic domains are functionally equivalent.Mouse genetics suggests cell-context dependency for Myc-regulated metabolic enzymes during tumorigenesisDeregulation of common genes by c-Myc and its direct target, MT-MC1.Myc, mondo, and metabolismSerine catabolism regulates mitochondrial redox control during hypoxiaShmt1 and de novo thymidylate biosynthesis underlie folate-responsive neural tube defects in mice.A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest.Direct role of nucleotide metabolism in C-MYC-dependent proliferation of melanoma cellsThe molecular determinants of de novo nucleotide biosynthesis in cancer cellsBioinformatics analysis of the serine and glycine pathway in cancer cellsA strategy for identifying transcription factor binding sites reveals two classes of genomic c-Myc target sites.Proteomic identification of mitochondrial targets of arginase in human breast cancer.18F-fluorodeoxy-glucose positron emission tomography marks MYC-overexpressing human basal-like breast cancersGenome-wide mapping of Myc binding and gene regulation in serum-stimulated fibroblasts.In vivo (1)H MRSI of glycine in brain tumors at 3T.Calreticulin expression in the clonal plasma cells of patients with systemic light-chain (AL-) amyloidosis is associated with response to high-dose melphalan.Metabolite profiling identifies a key role for glycine in rapid cancer cell proliferationIsotopically nonstationary 13C flux analysis of Myc-induced metabolic reprogramming in B-cells.HIF and c-Myc: sibling rivals for control of cancer cell metabolism and proliferationThe TCA cycle transferase DLST is important for MYC-mediated leukemogenesis.MYC, metabolism, cell growth, and tumorigenesis.Targeting MTHFD2 in acute myeloid leukemiaA c-Myc-SIRT1 feedback loop regulates cell growth and transformation.Is cancer a disease of abnormal cellular metabolism? New angles on an old idea
P2860
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P2860
A functional screen for Myc-responsive genes reveals serine hydroxymethyltransferase, a major source of the one-carbon unit for cell metabolism
description
2002 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2002 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2002
@ast
im August 2002 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2002/08/01)
@sk
vědecký článek publikovaný v roce 2002
@cs
wetenschappelijk artikel (gepubliceerd op 2002/08/01)
@nl
наукова стаття, опублікована в серпні 2002
@uk
مقالة علمية (نشرت في أغسطس 2002)
@ar
name
A functional screen for Myc-re ...... arbon unit for cell metabolism
@ast
A functional screen for Myc-re ...... arbon unit for cell metabolism
@en
A functional screen for Myc-re ...... arbon unit for cell metabolism
@nl
type
label
A functional screen for Myc-re ...... arbon unit for cell metabolism
@ast
A functional screen for Myc-re ...... arbon unit for cell metabolism
@en
A functional screen for Myc-re ...... arbon unit for cell metabolism
@nl
prefLabel
A functional screen for Myc-re ...... arbon unit for cell metabolism
@ast
A functional screen for Myc-re ...... arbon unit for cell metabolism
@en
A functional screen for Myc-re ...... arbon unit for cell metabolism
@nl
P2093
P2860
P3181
P1476
A functional screen for Myc-re ...... arbon unit for cell metabolism
@en
P2093
Andrew Beavis
Brenda O'Connell
Iulia Kotenko
John M Sedivy
Michael D Cole
Mikhail A Nikiforov
Oleksi Petrenko
P2860
P304
P3181
P356
10.1128/MCB.22.16.5793-5800.2002
P407
P577
2002-08-01T00:00:00Z