A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
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Sirtuins: molecular traffic lights in the crossroad of oxidative stress, chromatin remodeling, and transcriptionDYRK1A and DYRK3 promote cell survival through phosphorylation and activation of SIRT1A high-confidence interaction map identifies SIRT1 as a mediator of acetylation of USP22 and the SAGA coactivator complexThe Epigenetic Pathways to Ribosomal DNA SilencingSirtuin 1 and sirtuin 3: physiological modulators of metabolismAging and injury: alterations in cellular energetics and organ functionInterplay between sirtuins, MYC and hypoxia-inducible factor in cancer-associated metabolic reprogrammingLysine deacetylase (KDAC) regulatory pathways: an alternative approach to selective modulationFrom sirtuin biology to human diseases: an updateSirtuins in epigenetic regulationModulation of tumorigenesis by dietary intervention is not mediated by SIRT1 catalytic activityMitochondrial function in hypoxic ischemic injury and influence of agingResveratrol improves cardiac contractility following trauma-hemorrhage by modulating Sirt1SIRT1 is a critical regulator of K562 cell growth, survival, and differentiationMammalian sirtuins: biological insights and disease relevanceThe class III histone deacetylase sirtuin 1 in immune suppression and its therapeutic potential in rheumatoid arthritis.Desynchronization of Circadian Clocks in Cancer: A Metabolic and Epigenetic Connection.Sirtuins: guardians of mammalian healthspan.β2-AR activation induces chemoresistance by modulating p53 acetylation through upregulating Sirt1 in cervical cancer cells.Sirtuin 1 inhibition delays cyst formation in autosomal-dominant polycystic kidney diseaseSirtuins, melatonin and circadian rhythms: building a bridge between aging and cancer.SIRT1 and c-Myc promote liver tumor cell survival and predict poor survival of human hepatocellular carcinomas.Correlation and prognostic value of SIRT1 and Notch1 signaling in breast cancerThe molecular genetics of sirtuins: association with human longevity and age-related diseasesSorting out functions of sirtuins in cancerSIRT1 activation by a c-MYC oncogenic network promotes the maintenance and drug resistance of human FLT3-ITD acute myeloid leukemia stem cells.Activation of GSK3β by Sirt2 is required for early lineage commitment of mouse embryonic stem cell.SIRT1 catalytic activity has little effect on tumor formation and metastases in a mouse model of breast cancer.The expression of DBC1/CCAR2 is associated with poor prognosis of ovarian carcinomaInfluence of aging and hemorrhage injury on Sirt1 expression: possible role of myc-Sirt1 regulation in mitochondrial functionThe expression and correlation of SIRT1 and Phospho-SIRT1 in colorectal cancer.An unexpected role for caspase-2 in neuroblastoma.The c-MYC oncoprotein, the NAMPT enzyme, the SIRT1-inhibitor DBC1, and the SIRT1 deacetylase form a positive feedback loop.Activation of stress response gene SIRT1 by BCR-ABL promotes leukemogenesis.Hepatic deletion of SIRT1 decreases hepatocyte nuclear factor 1α/farnesoid X receptor signaling and induces formation of cholesterol gallstones in mice.ELL targets c-Myc for proteasomal degradation and suppresses tumour growth.The sirtuins in the pathogenesis of cancer.Protein deacetylation by sirtuins: delineating a post-translational regulatory program responsive to nutrient and redox stressorsAn autoregulatory loop reverts the mechanosensitive Sirt1 induction by EGR1 in skeletal muscle cellsSirtuin biology and relevance to diabetes treatment.
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A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
description
article científic
@ca
article scientifique
@fr
articolo scientifico
@it
artigo científico
@pt
bilimsel makale
@tr
scientific article published on 13 April 2009
@en
vedecký článok
@sk
vetenskaplig artikel
@sv
videnskabelig artikel
@da
vědecký článek
@cs
name
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
@en
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
@nl
type
label
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
@en
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
@nl
prefLabel
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
@en
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation.
@nl
P2860
P356
P1476
A c-Myc-SIRT1 feedback loop regulates cell growth and transformation
@en
P2093
Katherine Minter-Dykhouse
Zhenkun Lou
P2860
P304
P356
10.1083/JCB.200809167
P407
P50
P577
2009-04-13T00:00:00Z