Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles
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The sterol-sensing endoplasmic reticulum (ER) membrane protein TRC8 hampers ER to Golgi transport of sterol regulatory element-binding protein-2 (SREBP-2)/SREBP cleavage-activated protein and reduces SREBP-2 cleavageSirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular EffectsTranscriptional regulation of hepatic lipogenesisSterol Regulatory Element-Binding Proteins (SREBP) signallingInsulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex.Transcriptional control of hepatic lipid metabolism by SREBP and ChREBP.Dysregulation of sterol regulatory element binding protein-1c in livers of morbidly obese women is associated with altered suppressor of cytokine signaling-3 and signal transducer and activator of transcription-1 signaling.E4orf1 improves lipid and glucose metabolism in hepatocytes: a template to improve steatosis & hyperglycemia.Microarray characterization of gene expression changes in blood during acute ethanol exposureA Drosophila metallophosphoesterase mediates deglycosylation of rhodopsin.Analysis of transcription factor network underlying 3T3-L1 adipocyte differentiation.Endoplasmic reticulum stress and lipid metabolism: mechanisms and therapeutic potentialFoxO1 inhibits sterol regulatory element-binding protein-1c (SREBP-1c) gene expression via transcription factors Sp1 and SREBP-1c.Akt3 deficiency in macrophages promotes foam cell formation and atherosclerosis in miceEndoproteolytic cleavage of TUG protein regulates GLUT4 glucose transporter translocationTolfenamic acid suppresses cytochrome P450 2E1 expression in mouse liverGlycogen synthase kinase-3-mediated phosphorylation of serine 73 targets sterol response element binding protein-1c (SREBP-1c) for proteasomal degradationCideB protein is required for the biogenesis of very low density lipoprotein (VLDL) transport vesiclePhosphatidylinositol-3,4,5-triphosphate and cellular signaling: implications for obesity and diabetes.De novo lipogenesis in the liver in health and disease: more than just a shunting yard for glucoseA novel JNK2/SREBP-1c pathway involved in insulin-induced fatty acid synthesis in human adipocytes.E4BP4 is an insulin-induced stabilizer of nuclear SREBP-1c and promotes SREBP-1c-mediated lipogenesis.Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation.High Fat Diet Regulation of β-Cell Proliferation and β-Cell Mass.MicroRNA-124 promotes hepatic triglyceride accumulation through targeting tribbles homolog 3.Evolutionary conservation and adaptation in the mechanism that regulates SREBP action: what a long, strange tRIP it's beenEmergent properties of proteostasis-COPII coupled systems in human health and disease.Regulation of the SREBP transcription factors by mTORC1.SREBPs: metabolic integrators in physiology and metabolism.A pathway approach to investigate the function and regulation of SREBPs.Time of day and nutrients in feeding govern daily expression rhythms of the gene for sterol regulatory element-binding protein (SREBP)-1 in the mouse liverMolecular mechanisms of fatty liver in obesity.The interplay between cell signalling and the mevalonate pathway in cancer.Taurine is a liver X receptor-α ligand and activates transcription of key genes in the reverse cholesterol transport without inducing hepatic lipogenesis.Glucagon regulates hepatic lipid metabolism via cAMP and Insig-2 signaling: implication for the pathogenesis of hypertriglyceridemia and hepatic steatosisA novel role for CRTC2 in hepatic cholesterol synthesis through SREBP-2.MicroRNAs in metabolism and metabolic diseases.GSK-3-mediated phosphorylation couples ER-Golgi transport and nuclear stabilization of the CREB-H transcription factor to mediate apolipoprotein secretionSREBP-1 Mediates Angiotensin II-Induced TGF-β1 Upregulation and Glomerular Fibrosis.PAS kinase drives lipogenesis through SREBP-1 maturation.
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P2860
Insulin enhances post-translational processing of nascent SREBP-1c by promoting its phosphorylation and association with COPII vesicles
description
2009 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի մարտին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2009
@ast
im März 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/03/20)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/03/20)
@nl
наукова стаття, опублікована в березні 2009
@uk
name
Insulin enhances post-translat ...... ssociation with COPII vesicles
@ast
Insulin enhances post-translat ...... ssociation with COPII vesicles
@en
Insulin enhances post-translat ...... ssociation with COPII vesicles
@nl
type
label
Insulin enhances post-translat ...... ssociation with COPII vesicles
@ast
Insulin enhances post-translat ...... ssociation with COPII vesicles
@en
Insulin enhances post-translat ...... ssociation with COPII vesicles
@nl
prefLabel
Insulin enhances post-translat ...... ssociation with COPII vesicles
@ast
Insulin enhances post-translat ...... ssociation with COPII vesicles
@en
Insulin enhances post-translat ...... ssociation with COPII vesicles
@nl
P2093
P2860
P3181
P356
P1476
Insulin enhances post-translat ...... ssociation with COPII vesicles
@en
P2093
Chandrahasa R. Yellaturu
Charles M. Mansbach
Edwards A. Park
Henry G. Wilcox
Lauren M. Cagen
Marshall B. Elam
Rajendra Raghow
Shadab A. Siddiqi
Xiong Deng
P2860
P304
P3181
P356
10.1074/JBC.M805746200
P407
P577
2009-03-20T00:00:00Z