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Regulation of the SREBP transcription factors by mTORC1.

Regulation of the SREBP transcription factors by mTORC1.

http://www.wikidata.org/entity/Q37856383

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Linking diet to acne metabolomics, inflammation, and comedogenesis: an update Role of the Enterocyte in Fructose-Induced Hypertriglyceridaemia Topics in transcriptional control of lipid metabolism: from transcription factors to gene-promoter polymorphisms.Linoleic and α-linolenic fatty acid consumption over three generations exert cumulative regulation of hepatic expression of genes related to lipid metabolism.Signaling networks converge on TORC1-SREBP activity to promote endoplasmic reticulum homeostasis.The Flavone Luteolin Suppresses SREBP-2 Expression and Post-Translational Activation in Hepatic Cells Cell cycle progression is an essential regulatory component of phospholipid metabolism and membrane homeostasis.Inhibition of mTOR complex 2 induces GSK3/FBXW7-dependent degradation of sterol regulatory element-binding protein 1 (SREBP1) and suppresses lipogenesis in cancer cells.Diacylglycerol kinase-ζ regulates mTORC1 and lipogenic metabolism in cancer cells through SREBP-1 Luteinizing hormone/human chorionic gonadotropin-mediated activation of mTORC1 signaling is required for androgen synthesis by theca-interstitial cells.Cellular fatty acid metabolism and cancer mTOR Signalling in Health and Disease.Exploring the emerging complexity in transcriptional regulation of energy homeostasis.mTORC1 promotes proliferation of immature Schwann cells and myelin growth of differentiated Schwann cells.The flavone apigenin blocks nuclear translocation of sterol regulatory element-binding protein-2 in the hepatic cells WRL-68.Fatty acid elongase 7 catalyzes lipidome remodeling essential for human cytomegalovirus replication.Silibinin inhibits aberrant lipid metabolism, proliferation and emergence of androgen-independence in prostate cancer cells via primarily targeting the sterol response element binding protein 1.The HDL receptor SR-BI is associated with human prostate cancer progression and plays a possible role in establishing androgen independence.Jatropha curcas Protein Concentrate Stimulates Insulin Signaling, Lipogenesis, Protein Synthesis and the PKCα Pathway in Rat Liver.High Dietary Selenium Intake Alters Lipid Metabolism and Protein Synthesis in Liver and Muscle of Pigs.MicroRNAs in metabolism and metabolic diseases.Sterol regulatory element binding protein-dependent regulation of lipid synthesis supports cell survival and tumor growth.Effects of SIRT1 gene knock-out via activation of SREBP2 protein-mediated PI3K/AKT signaling on osteoarthritis in mice.Fatty acid synthase is required for profibrotic TGF-β signaling.New links between lipid accumulation and cancer progression.Role of SREBPs in Liver Diseases: A Mini-review

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Regulation of the SREBP transcription factors by mTORC1.

http://www.wikidata.org/entity/Q37856383

description

article científic

@ca

article scientifique

@fr

articolo scientifico

@it

artigo científico

@pt

bilimsel makale

@tr

scientific article published on April 2011

@en

vedecký článok

@sk

vetenskaplig artikel

@sv

videnskabelig artikel

@da

vědecký článek

@cs

name

Regulation of the SREBP transcription factors by mTORC1.

@en

Regulation of the SREBP transcription factors by mTORC1.

@nl

type

label

Regulation of the SREBP transcription factors by mTORC1.

@en

Regulation of the SREBP transcription factors by mTORC1.

@nl

prefLabel

Regulation of the SREBP transcription factors by mTORC1.

@en

Regulation of the SREBP transcription factors by mTORC1.

@nl

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Biochemical Society Transactions

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Regulation of the SREBP transcription factors by mTORC1.

@en

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Beatrice Griffiths

http://www.w3.org/2001/XMLSchema#string

Caroline A Lewis

http://www.w3.org/2001/XMLSchema#string

Claudio R Santos

http://www.w3.org/2001/XMLSchema#string

Mario Pende

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P2860

The TRC8 ubiquitin ligase is sterol regulated and interacts with lipid and protein biosynthetic pathways

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

SREBP activity is regulated by mTORC1 and contributes to Akt-dependent cell growth

SREBP-1, a membrane-bound transcription factor released by sterol-regulated proteolysis

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

Identification of complexes between the COOH-terminal domains of sterol regulatory element-binding proteins (SREBPs) and SREBP cleavage-activating protein

S6K1(-/-)/S6K2(-/-) mice exhibit perinatal lethality and rapamycin-sensitive 5'-terminal oligopyrimidine mRNA translation and reveal a mitogen-activated protein kinase-dependent S6 kinase pathway

AKT/PKB signaling: navigating downstream

Combined analysis of oligonucleotide microarray data from transgenic and knockout mice identifies direct SREBP target genes

TOS motif-mediated raptor binding regulates 4E-BP1 multisite phosphorylation and function

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495-499

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scholarly article

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10.1042/BST0390495

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2

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39

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2011-04-01T00:00:00Z

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21428927

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