Troponin T modulates sarcomere length-dependent recruitment of cross-bridges in cardiac muscle.
about
Myostatin represses physiological hypertrophy of the heart and excitation-contraction couplingIntegration of troponin I phosphorylation with cardiac regulatory networksFunctional consequence of mutation in rat cardiac troponin T is affected differently by myosin heavy chain isoformsFRET study of the structural and kinetic effects of PKC phosphomimetic cardiac troponin T mutants on thin filament regulation.Structural and kinetic effects of PAK3 phosphorylation mimic of cTnI(S151E) on the cTnC-cTnI interaction in the cardiac thin filamentModel representation of the nonlinear step response in cardiac muscle.Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation.Body weight-dependent troponin T alternative splicing is evolutionarily conserved from insects to mammals and is partially impaired in skeletal muscle of obese rats.Human slow troponin T (TNNT1) pre-mRNA alternative splicing is an indicator of skeletal muscle response to resistance exercise in older adults.The functional effect of dilated cardiomyopathy mutation (R144W) in mouse cardiac troponin T is differently affected by α- and β-myosin heavy chain isoformsAlanine or aspartic acid substitutions at serine23/24 of cardiac troponin I decrease thin filament activation, with no effect on crossbridge detachment kineticsThe N-terminal extension of cardiac troponin T stabilizes the blocked state of cardiac thin filamentCardiomyopathy-Related Mutations in Cardiac Troponin C, L29Q and G159D, Have Divergent Effects on Rat Cardiac Myofiber Contractile Dynamics.Enhanced Ca2+ binding of cardiac troponin reduces sarcomere length dependence of contractile activation independently of strong crossbridges.Rat cardiac troponin T mutation (F72L)-mediated impact on thin filament cooperativity is divergently modulated by α- and β-myosin heavy chain isoforms.The functional properties of human slow skeletal troponin T isoforms in cardiac muscle regulation.A Priori Identifiability Analysis of Cardiovascular Models.Troponin and titin coordinately regulate length-dependent activation in skinned porcine ventricular muscleDeletion of 1-43 amino acids in cardiac myosin essential light chain blunts length dependency of Ca(2+) sensitivity and cross-bridge detachment kinetics.Quantitative and evolutionary biology of alternative splicing: how changing the mix of alternative transcripts affects phenotypic plasticity and reaction norms.Structural and kinetic effects of hypertrophic cardiomyopathy related mutations R146G/Q and R163W on the regulatory switching activity of rat cardiac troponin IThe tropomyosin binding region of cardiac troponin T modulates crossbridge recruitment dynamics in rat cardiac muscle fibers.Interplay Between the Effects of Dilated Cardiomyopathy Mutation (R206L) and the Protein Kinase C Phosphomimic (T204E) of Rat Cardiac Troponin T Are Differently Modulated by α- and β-Myosin Heavy Chain Isoforms.Interplay between the overlapping ends of tropomyosin and the N terminus of cardiac troponin T affects tropomyosin states on actinDivergent effects of α- and β-myosin heavy chain isoforms on the N terminus of rat cardiac troponin T.Protein kinase A-dependent modulation of Ca2+ sensitivity in cardiac and fast skeletal muscles after reconstitution with cardiac troponin.Instability in the central region of tropomyosin modulates the function of its overlapping ends.Dilated Cardiomyopathy Mutation (R134W) in Mouse Cardiac Troponin T Induces Greater Contractile Deficits against α-Myosin Heavy Chain than against β-Myosin Heavy Chain.Cardiomyopathy-related mutation (A30V) in mouse cardiac troponin T divergently alters the magnitude of stretch activation in α- and β-myosin heavy chain fibers.Interplay between the effects of a Protein Kinase C phosphomimic (T204E) and a dilated cardiomyopathy mutation (K211Δ or R206W) in rat cardiac troponin T blunts the magnitude of muscle length-mediated crossbridge recruitment against the β-myosin heaLength-dependent effects on cardiac contractile dynamics are different in cardiac muscle containing α- or β-myosin heavy chain.Contributions of stretch activation to length-dependent contraction in murine myocardium.Molecular plasticity and functional enhancements of leg muscles in response to hypergravity in the fruit fly Drosophila melanogaster.The effect of cardiomyopathy mutation (R97L) in mouse cardiac troponin T on the muscle length-mediated recruitment of crossbridges is modified divergently by α- and β-myosin heavy chain.Omecamtiv Mecarbil Abolishes Length-Mediated Increase in Guinea Pig Cardiac Myofiber Ca2+ Sensitivity.Hypertrophic cardiomyopathy mutation in cardiac troponin T (R95H) attenuates length-dependent activation in guinea pig cardiac muscle fibers.Effects of pseudo-phosphorylated rat cardiac troponin T are differently modulated by α- and β-myosin heavy chain isoforms.Cardiomyopathy mutation (F88L) in troponin T abolishes length dependency of myofilament Ca sensitivity
P2860
Q24647028-387FF609-6F05-4CA4-A1B6-A3CA11521247Q26852120-48BEE3BE-9917-4D8D-9EF3-A2ABF73135B1Q28580787-9F9CD19D-303B-41ED-8BA1-882A1A32D7E1Q33762306-1A9576DA-3437-4695-AB7F-33139877A222Q34024565-ECFB1785-86C8-449D-B5C2-53568D2056A0Q34028229-CAFC4B5F-9FE3-4637-9444-2E670C5088BBQ34608313-019FC575-35E4-4EA1-A614-05ECCF187058Q34789287-D6DCF7FE-4D1B-48E5-9AEF-466137F061A5Q34974513-B061822B-65D7-472B-80FF-CB07FFD3AE66Q35437348-77D113CF-A7F3-49EB-AC27-7CBD50FB736BQ36117053-8D857A4F-200A-4101-ABC6-141FDF46623EQ36207947-B2EA50F0-A5E6-4167-8D19-6A4955DE2168Q36248424-116DD6DA-BBFC-48C9-A4D9-F75AAD25FFDCQ36312744-6A0E25C8-23B0-4083-8FD5-FC4B045FD6E2Q36339391-79281BEE-A49D-4636-BD92-AD7C7F39291AQ36347849-9B5C96BF-55BB-4860-97AB-C6AF0278C375Q36418270-96ACB05B-E5D1-44CC-AD9D-DF1CD1B3829AQ36471317-06503D2D-E7C5-4BC3-844C-156C83A5A706Q36528078-F1056887-FC6E-4CDD-BC59-1E8BFF6DFFF5Q36605975-58F0C004-480A-48A9-9753-6F8B40F2DDB2Q36739221-BF465C68-76C5-466E-B379-869D6197585BQ36788034-88A21C42-BBF8-4F6E-B949-1B4503E2023EQ37090750-C1802F83-2EF8-494D-87DC-A3FB2928062DQ37118797-5EDBC256-9292-4AAA-854A-90445F44D27BQ37209216-D65ED536-14F4-45AA-B304-07A973B70B4CQ37268151-4E44E3FD-4269-4231-869B-97FF5B33D80AQ37299705-525AB636-4963-4314-8A82-1539F23DAAC4Q37306367-C4355D63-181E-4062-8C38-F32A12753235Q39260207-CC58D664-7802-40D2-A961-8CD8232EAF2CQ39605306-3CBD0D83-F952-4D6F-9B74-A0AD1F650B28Q40265069-C57F1440-9DE4-4180-A6BF-05CCDCB3C26CQ41839713-961647AE-CFFC-4D12-BE22-1A85494A7A5AQ41985772-0B078434-5F89-48B4-9B01-328B20653EC7Q41997993-C72B5267-743A-4FD9-B0CA-810F00DB2AB1Q46650156-E5EB72C8-A9B1-4967-9978-0053476A61B9Q47904402-F25CE3F8-4221-4C54-8CEC-9A3E02BD7E28Q55070756-56FAB7DC-4C98-4001-80D5-BEC333550326Q57095885-6E524DF2-A7AD-4E4F-BFD3-2B57477E27F8
P2860
Troponin T modulates sarcomere length-dependent recruitment of cross-bridges in cardiac muscle.
description
2006 nî lūn-bûn
@nan
2006 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2006年の論文
@ja
2006年学术文章
@wuu
2006年学术文章
@zh-cn
2006年学术文章
@zh-hans
2006年学术文章
@zh-my
2006年学术文章
@zh-sg
2006年學術文章
@yue
name
Troponin T modulates sarcomere ...... ross-bridges in cardiac muscle
@nl
Troponin T modulates sarcomere ...... oss-bridges in cardiac muscle.
@ast
Troponin T modulates sarcomere ...... oss-bridges in cardiac muscle.
@en
type
label
Troponin T modulates sarcomere ...... ross-bridges in cardiac muscle
@nl
Troponin T modulates sarcomere ...... oss-bridges in cardiac muscle.
@ast
Troponin T modulates sarcomere ...... oss-bridges in cardiac muscle.
@en
prefLabel
Troponin T modulates sarcomere ...... ross-bridges in cardiac muscle
@nl
Troponin T modulates sarcomere ...... oss-bridges in cardiac muscle.
@ast
Troponin T modulates sarcomere ...... oss-bridges in cardiac muscle.
@en
P2093
P2860
P3181
P1433
P1476
Troponin T modulates sarcomere ...... oss-bridges in cardiac muscle.
@en
P2093
Indika Rajapakse
Kenneth B Campbell
Matthew L Tschirgi
Murali Chandra
P2860
P304
P3181
P356
10.1529/BIOPHYSJ.105.076950
P407
P577
2006-01-27T00:00:00Z