Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
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Nedd4-2 and the regulation of epithelial sodium transportCOMMD1 downregulates the epithelial sodium channel through Nedd4-2Nedd4 and Nedd4-2: closely related ubiquitin-protein ligases with distinct physiological functionsPKB/Akt partners with Dab2 in albumin endocytosisAS160 modulates aldosterone-stimulated epithelial sodium channel forward traffickingIncreased gut permeability and microbiota change associate with mesenteric fat inflammation and metabolic dysfunction in diet-induced obese miceSGK1: The Dark Side of PI3K Signaling.Targeting SGK1 in diabetesThe physiological impact of the serum and glucocorticoid-inducible kinase SGK1Regulation of sodium transport by ENaC in the kidneyPhosphopeptide screen uncovers novel phosphorylation sites of Nedd4-2 that potentiate its inhibition of the epithelial Na+ channel.Regulation of renal tubular glucose reabsorption by Akt2/PKBβAcute insulin stimulation induces phosphorylation of the Na-Cl cotransporter in cultured distal mpkDCT cells and mouse kidney.Regulation of the epithelial sodium channel (ENaC) by membrane traffickingAMP-activated protein kinase inhibits KCNQ1 channels through regulation of the ubiquitin ligase Nedd4-2 in renal epithelial cells.An APPL1/Akt signaling complex regulates dendritic spine and synapse formation in hippocampal neuronsActivation of PI3-kinase stimulates endocytosis of ROMK via Akt1/SGK1-dependent phosphorylation of WNK1.The association between dietary sodium intake, ESRD, and all-cause mortality in patients with type 1 diabetes.Insulin activates epithelial sodium channel (ENaC) via phosphoinositide 3-kinase in mammalian taste receptor cells.Regulation of the epithelial Na+ channel by the RH domain of G protein-coupled receptor kinase, GRK2, and Galphaq/11.H-Ras mediates the inhibitory effect of epidermal growth factor on the epithelial Na+ channelNedd4-2 modulates renal Na+-Cl- cotransporter via the aldosterone-SGK1-Nedd4-2 pathway.mTORC2 regulates renal tubule sodium uptake by promoting ENaC activity.Oral administration of Saccharomyces boulardii ameliorates carbon tetrachloride-induced liver fibrosis in rats via reducing intestinal permeability and modulating gut microbial composition.Neural precursor cell-expressed developmentally down-regulated protein 4-2 (Nedd4-2) regulation by 14-3-3 protein binding at canonical serum and glucocorticoid kinase 1 (SGK1) phosphorylation sites.Fecal microbiota transplantation and bacterial consortium transplantation have comparable effects on the re-establishment of mucosal barrier function in mice with intestinal dysbiosis.Regulation of ENaC-mediated alveolar fluid clearance by insulin via PI3K/Akt pathway in LPS-induced acute lung injuryEpithelial Na⁺ channel activity in human airway epithelial cells: the role of serum and glucocorticoid-inducible kinase 1.Regulation of transport in the connecting tubule and cortical collecting ductActivity of the p110-alpha subunit of phosphatidylinositol-3-kinase is required for activation of epithelial sodium transport.Ubiquitination-mediated internalization and degradation of the astroglial glutamate transporter, GLT-1Modulation of sodium iodide symporter expression and function by LY294002, Akti-1/2 and Rapamycin in thyroid cellsRenal tubular epithelial cell prorenin receptor regulates blood pressure and sodium transport.A new SGK1 knockout mouse.The activity of the epithelial sodium channels is regulated by caveolin-1 via a Nedd4-2-dependent mechanism.A phosphoinositide 3-kinase (PI3K)-serum- and glucocorticoid-inducible kinase 1 (SGK1) pathway promotes Kv7.1 channel surface expression by inhibiting Nedd4-2 protein.ULK1 cycling: The ups and downs of the autophagy response.Rapid elevation of sodium transport through insulin is mediated by AKT in alveolar cells.The Dual Role of TNF in Pulmonary Edema.Molecular physiology of the medullary collecting duct.
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P2860
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
description
2007 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2007
@ast
im Oktober 2007 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2007/10/12)
@sk
vědecký článek publikovaný v roce 2007
@cs
wetenschappelijk artikel (gepubliceerd op 2007/10/12)
@nl
наукова стаття, опублікована в жовтні 2007
@uk
name
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@ast
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@en
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@nl
type
label
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@ast
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@en
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@nl
prefLabel
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@ast
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@en
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@nl
P2093
P2860
P921
P3181
P356
P1476
Akt mediates the effect of insulin on epithelial sodium channels by inhibiting Nedd4-2
@en
P2093
Angeles Sanchez-Perez
Anuwat Dinudom
David I. Cook
P2860
P304
29866–29873
P3181
P356
10.1074/JBC.M701923200
P407
P50
P577
2007-10-12T00:00:00Z