Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
about
The DNA binding parvulin Par17 is targeted to the mitochondrial matrix by a recently evolved prepeptide uniquely present in HominidaeAn OBSL1-Cul7Fbxw8 ubiquitin ligase signaling mechanism regulates Golgi morphology and dendrite patterningNerve growth factor stimulates interaction of Cayman ataxia protein BNIP-H/Caytaxin with peptidyl-prolyl isomerase Pin1 in differentiating neuronsIdentification of ROCK1 as an upstream activator of the JIP-3 to JNK signaling axis in response to UVB damageNuclear import of Pin1 is mediated by a novel sequence in the PPIase domainRegulation of Bim in Health and DiseasePostnatal developmental regulation of Bcl-2 family proteins in brain mitochondriaProlyl isomerase Pin1 regulates neuronal differentiation via β-cateninc-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82The peptidyl-prolyl isomerase Pin1 facilitates cytokine-induced survival of eosinophils by suppressing Bax activation.Phosphorylation stabilizes Nanog by promoting its interaction with Pin1Pin1 and PKMzeta sequentially control dendritic protein synthesis.Inhibition of Pin1 reduces glutamate-induced perikaryal accumulation of phosphorylated neurofilament-H in neurons.Opposite regulation of oligodendrocyte apoptosis by JNK3 and Pin1 after spinal cord injuryCurcumin inhibition of JNKs prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease through suppressing mitochondria dysfunction.Pin1-dependent prolyl isomerization modulates the stress-induced phosphorylation of high molecular weight neurofilament protein.ULK1 and JNK are involved in mitophagy incurred by LRRK2 G2019S expression.Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity.What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain.The peptidyl-prolyl isomerase Pin1 up-regulation and proapoptotic function in dopaminergic neurons: relevance to the pathogenesis of Parkinson disease.A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells.Sunday driver interacts with two distinct classes of axonal organelles.Hyperthermia stress activates heat shock protein expression via propyl isomerase 1 regulation with heat shock factor 1.ERK and cell death: ERK location and T cell selection.JNK: a stress-activated protein kinase therapeutic strategies and involvement in Alzheimer's and various neurodegenerative abnormalities.Gephyrin phosphorylation in the functional organization and plasticity of GABAergic synapses.The prolyl-isomerase Pin1 activates the mitochondrial death program of p53Regulation of neuronal cell death by MST1-FOXO1 signaling.Pin1 in neuronal apoptosis.Small peptide inhibitor of JNKs protects against MPTP-induced nigral dopaminergic injury via inhibiting the JNK-signaling pathway.A suppressive role of the prolyl isomerase Pin1 in cellular apoptosis mediated by the death-associated protein Daxx.Glutaredoxin 1 mediates the protective effect of steady laminar flow on endothelial cells against oxidative stress-induced apoptosis via inhibiting Bim.Protein interacting with NIMA (never in mitosis A)-1 regulates axonal growth cone adhesion and spreading through myristoylated alanine-rich C kinase substrate isomerization.Chaperone-E3 Ligase Complex HSP70-CHIP Mediates Ubiquitination of Ribosomal Protein S3
P2860
Q24293963-7B711242-2AF6-4D33-8009-53A2A17B2CA7Q24302459-5065246D-727D-4165-B562-AF286FEDFC3BQ24313838-152D2DD9-8E71-4EE2-9D88-67FE84C5A85EQ24318504-47397F29-4578-48AD-A796-7706956594FEQ24336290-5A16D7F9-F6AF-4D8B-B360-EF61BAC5160BQ26781203-BB94D4FA-D4FB-4C65-9E76-644CBD657249Q28572255-4CBA0510-93A4-4EA7-90A6-694E21ECC8DAQ28586339-0A6E98AE-A4A8-41D9-8061-D5A0C8931BF2Q33673579-41D3E56C-9156-4B50-9295-04946D104052Q33762811-84D79D3A-7F1D-4B12-BEE5-9BD6E1B3938FQ34068097-061C8EDF-A35A-4B6A-A6AE-2E6AA8B0481AQ34274733-004ADBC3-331C-48B8-AC80-D3B4BF33A176Q35949035-6BB6B0F9-1453-4392-BC72-2B779D425BF3Q36108225-A95D3D25-97A2-40B0-8515-F960EEF85B73Q36444557-00CFA664-6C57-4E27-9816-B9FBFB47C2BEQ36897651-F4DA9F7F-69F9-4552-97CA-37848477A0CAQ36923141-F12716FB-BEF9-4E62-9C0C-C4217ECF4C32Q36953129-80B31DB4-ECBB-4DAC-81B4-771A433C5F2CQ37008257-E49F0780-A6D4-43A9-A799-B2F9C4332AB3Q37048463-DAE1FA73-217E-4658-8625-E27F22DF400DQ37257665-F1DFC704-982D-4767-8FA3-B49F7BFF3AEAQ37454186-BD5C2F83-6B7A-4D3B-B01F-517F39D5678AQ37469442-58638B0C-4F30-47D4-BF79-4935B0FE128BQ37618290-217573EA-C568-480D-84FC-1C7EAC232A39Q37793978-1BBC7322-7F30-449B-BC88-B71A29463AFCQ38208292-E4AF6F69-758C-4A5E-B268-33099D01BDC4Q39288084-B9832983-4DA1-4375-ABB2-BED931B888C6Q39883289-3E291C4A-41A5-4FB2-8538-37AA387E193FQ42091009-D263F5FA-53DD-4527-98AC-93A5F30B973CQ43221663-AC8F8546-5E3C-4AA8-83DD-A575549DBF1AQ46949438-88C9630E-3F9A-4461-8150-4358D47EB18DQ47121964-B6647EA0-18F3-4D81-9C38-7F48F831600AQ48825214-86791266-4179-4DDD-8459-487CF95EA119Q58745452-5FCB5781-68F7-4DD7-A6D7-F4D175041E5C
P2860
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
description
2006 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im März 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/03/02)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/03/02)
@nl
наукова стаття, опублікована в березні 2006
@uk
مقالة علمية (نشرت في 2-3-2006)
@ar
name
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@ast
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@en
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@nl
type
label
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@ast
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@en
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@nl
prefLabel
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@ast
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@en
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@nl
P1433
P1476
Pin1 mediates neural-specific activation of the mitochondrial apoptotic machinery
@en
P2093
Azad Bonni
P304
P356
10.1016/J.NEURON.2006.01.034
P407
P577
2006-03-01T00:00:00Z