What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain.
about
A novel TCR transgenic model reveals that negative selection involves an immediate, Bim-dependent pathway and a delayed, Bim-independent pathway.Genetic control of programmed cell death during animal development.B-CD8+ T Cell Interactions in the Anti-Idiotypic Response against a Self-Antibody.Bryostatin analogue-induced apoptosis in mantle cell lymphoma cell linesc-Cbl promotes T cell receptor-induced thymocyte apoptosis by activating the phosphatidylinositol 3-kinase/Akt pathway.IFN-α is constitutively expressed in the human thymus, but not in peripheral lymphoid organs.Fraternal twins: Swiprosin-1/EFhd2 and Swiprosin-2/EFhd1, two homologous EF-hand containing calcium binding adaptor proteins with distinct functions.Protein kinase C regulates mitochondrial targeting of Nur77 and its family member Nor-1 in thymocytes undergoing apoptosis.Inflammation-inducing Th1 and Th17 cells differ in their expression patterns of apoptosis-related molecules.Proapoptotic protein Bim is differentially required during thymic clonal deletion to ubiquitous versus tissue-restricted antigens.NR4A nuclear receptors in immunity and atherosclerosisFatigue-related gene networks identified in CD(14)+ cells isolated from HIV-infected patients: part I: research findings.Thymoproteasome subunit-β5T generates peptide-MHC complexes specialized for positive selection.A proapoptotic signaling pathway involving RasGRP, Erk, and Bim in B cells.How does Epstein-Barr virus (EBV) complement the activation of Myc in the pathogenesis of Burkitt's lymphoma?ERK and cell death: ERK location and T cell selection.Immunologic similarities between selected autoimmune diseases and peanut allergy: possible new therapeutic approaches.Apoptotic and nonapoptotic caspase functions in animal development.Who lives and who dies: Role of apoptosis in quashing developmental errors.B-cell tolerance and autoimmunity.Calcium Signaling: From Normal B Cell Development to Tolerance Breakdown and Autoimmunity.POSH Regulates CD4+ T Cell Differentiation and Survival.Integrin signaling in cancer cell survival and chemoresistanceAntigen-specific tolerance inhibits autoimmune uveitis in pre-sensitized animals by deletion and CD4+CD25+ T-regulatory cells.Interleukin-7 promotes the survival of human CD4+ effector/memory T cells by up-regulating Bcl-2 proteins and activating the JAK/STAT signalling pathway.Immune checkpoint inhibitor-related myocarditis.
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What do we know about the mechanisms of elimination of autoreactive T and B cells and what challenges remain.
description
2007 nî lūn-bûn
@nan
2007年の論文
@ja
2007年学术文章
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2007年学术文章
@zh-cn
2007年学术文章
@zh-hans
2007年学术文章
@zh-my
2007年学术文章
@zh-sg
2007年學術文章
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2007年學術文章
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2007年學術文章
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name
What do we know about the mech ...... ls and what challenges remain.
@en
What do we know about the mech ...... ls and what challenges remain.
@nl
type
label
What do we know about the mech ...... ls and what challenges remain.
@en
What do we know about the mech ...... ls and what challenges remain.
@nl
prefLabel
What do we know about the mech ...... ls and what challenges remain.
@en
What do we know about the mech ...... ls and what challenges remain.
@nl
P2860
P50
P356
P1476
What do we know about the mech ...... ls and what challenges remain.
@en
P2093
Lorraine A O'Reilly
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P2888
P356
10.1038/SJ.ICB.7100141
P577
2007-11-20T00:00:00Z
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P6179
1031504089